E 97 Expression of TLR9 and BD-2 protein genes in corneal cells of mice of different strains with herpetic keratitis / V. A. Chereshnev, L. V. Gankovskaya, L. V. Koval'chuk [et al.] // Bulletin of experimental biology and medicine. - 2012. - Vol. 153, № 2. - P236-239. - Bibliogr. : p. 239 (11 ref.) Рубрики: БИОЛОГИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): INNATE IMMUNITY -- HERPETIC INFECTION -- KERATITIS Аннотация: The dynamics of gene expression of two proteins, TLR9 (one of the key receptors recognizing CpG repeats of herpes virus DNA) and beta-defensin 2 (antibacterial peptide), was studied on the model of herpetic keratitis in C57Bl/6 and BALB/c mice. New data on differences in TLR9 gene expression in mice of the two strains infected with the virus were obtained. Reduced TLR9 gene expression in the cornea of C57Bl/6 mice was associated with their high sensitivity to infection caused by herpes simplex 1 virus \\\\expert2\\NBO\\Bulletin of Experimental Biology and Medicine\\2012, v.153, N 2, p. 236-239.pdf |