E 27 Effect of hepatitis C vIrus coinfection on the content of CD4+ and CD8+ T cell subpopulations in HIV-infected patients receiving antiretroviral therapy / L. B. Korolevskaya, K. V. Shmagel, E. V. Saidakova [et al.] // Bulletin of experimental biology and medicine. - 2016. - Vol. 161, № 2. - P281-283. - Bibliogr. : p. 283 (12 ref.) Рубрики: ЗДРАВООХРАНЕНИЕ--КЛИНИЧЕСКАЯ МЕДИЦИНА Кл.слова (ненормированные): HIV INFECTION -- HCV COINFECTION -- ANTIRETROVIRAL THERAPY -- T CELL SUBPOPULATIONS Аннотация: We studied the effect of hepatitis C virus coinfection on T cell subpopulations in HIV-infected patients receiving antiretroviral therapy. Coinfection with hepatitis C virus was followed by a decrease in the number of naive CD4+ T cells and an increase in the count of central CD8+ memory T cells in these patients. Hepatitis C virus had no effect on the number of CD4+ memory T cells (main target for HIV). This can explain the absence of strong negative effect of hepatitis C virus on the course of HIV infection. \\\\expert2\\NBO\\Bulletin of Experimental Biology and Medicine\\2016, v.161, N 2, p. 281-283.pdf |