Вид документа : Статья из журнала Шифр издания : 57/T 84 Автор(ы) : Kuyukina M. S., Ivshina I. B., Baeva T. A., Kochina O. A., Gein S. V., Chereshnev V. A. Заглавие : Trehalolipid biosurfactants from nonpathogenic Rhodococcus actinobacteria with diverse immunomodulatory activities Место публикации : New Biotechnology. - 2015. - V. 32., № 6. - С. 559-568 Примечания : Bibliogr. : p. 566-568 (82 ref.) ББК : 57 Предметные рубрики: БИОЛОГИЧЕСКИЕ НАУКИ Ключевые слова (''Своб.индексиров.''): immunological activities--trehalolipids--rhodococcus rubber Аннотация: Actinobacteria of the genus Rhodococcus produce trehalolipid biosurfactants with versatile biochemical properties and low toxicity. In recent years, these biosurfactants are increasingly studied as possible biomedical agents with expressed immunological activities. Applications of trehalolipids from Rhodococcus, predominantly cell-bound, in biomedicine are also attractive because their cost drawback could be less significant for high-value products. The review summarizes recent findings in immunomodulatory activities of trehalolipid biosurfactants from nonpathogenic Rhodococcus and related actinobacteria and compares their biomedical potential with well-known immunomodifying properties of trehalose dimycolates from Mycobacterium tuberculosis. Molecular mechanisms of trehalolipid interactions with immunocompetent cells are also discussed. Доп.точки доступа: Kuyukina, M. S.; Ivshina, I. B.; Baeva, T. A.; Kochina, O. A.; Gein, S. V.; Chereshnev, V. A.