Вид документа : Статья из журнала
Шифр издания : 61/E 27
Автор(ы) : Korolevskaya L. B., Shmagel K. V., Saidakova E. V., Shmagel N. G., Slobodchikova S. V., Chereshnev V. A.
Заглавие : Effect of hepatitis C vIrus coinfection on the content of CD4+ and CD8+ T cell subpopulations in HIV-infected patients receiving antiretroviral therapy
Место публикации : Bulletin of experimental biology and medicine. - 2016. - Vol. 161, № 2. - С. 281-283
Примечания : Bibliogr. : p. 283 (12 ref.)
ББК : 61
Предметные рубрики: ЗДРАВООХРАНЕНИЕ-- КЛИНИЧЕСКАЯ МЕДИЦИНА
Ключевые слова (''Своб.индексиров.''): hiv infection --hcv coinfection --antiretroviral therapy--t cell subpopulations
Аннотация: We studied the effect of hepatitis C virus coinfection on T cell subpopulations in HIV-infected patients receiving antiretroviral therapy. Coinfection with hepatitis C virus was followed by a decrease in the number of naive CD4+ T cells and an increase in the count of central CD8+ memory T cells in these patients. Hepatitis C virus had no effect on the number of CD4+ memory T cells (main target for HIV). This can explain the absence of strong negative effect of hepatitis C virus on the course of HIV infection.

Доп.точки доступа:
Korolevskaya, L. B.; Shmagel, K. V.; Saidakova, E. V.; Shmagel, N. G.; Slobodchikova, S. V.; Chereshnev, V. A.