Вид документа : Статья из журнала Шифр издания : 001.2/C 36 Автор(ы) : Saidakova E. V., Shmagel K. V., Korolevskaya L. B., Shmagel N. G., Chereshnev V. A. Заглавие : CD8.sup.+ T cell expansion in HIV/HCV coinfection is associated with systemic inflammation Место публикации : Doklady Biological Sciences. - 2017. - Vol. 474, № 1. - С. 126-128 ББК : 001.2 Предметные рубрики: НАУКА. НАУКОВЕДЕНИЕ Ключевые слова (''Своб.индексиров.''): hepatitis c -- risk factors--comorbidity -- risk factors--t cells--hepatitis c virus Аннотация: High prevalence of non-AIDS-defining illnesses in treated HIV-infected patients is associated with increased peripheral CD8.sup.+ T cell counts. Hepatitis C virus (HCV) coinfection is an additional risk factor for the development of non-AIDS events. We found that, in HIV/HCV coinfection, the increased proportion of CD8.sup.+ T lymphocytes is due to the effector memory and terminal effector T cells gain. Moreover, in these patients, the accumulation of highly differentiated forms of CD8.sup.+ T lymphocytes was associated with increased concentrations of inflammatory indices. Доп.точки доступа: Saidakova, E. V.; Shmagel, K. V.; Korolevskaya, L. B.; Shmagel, N. G.; Chereshnev, V. A.