Вид документа : Статья из журнала Шифр издания : 53 Автор(ы) : Zamorina S. A., Timganova V. P., Bochkova M. S., Khramtsov P. V., Fomicheva K. A., Rayev M. B., Chereshnev V. A. Заглавие : α-Fetoprotein influence on the conversion of naϊve T-helpers into memory T-cell effector subpopulations Место публикации : Doklady Biological Sciences. - 2018. - Vol. 482, № 1. - С. 210-213 ББК : 53 Предметные рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ Аннотация: The effect of native á-fetoprotein (AFP) on the conversion of naive T-helpers into central memory T-cells (TCM) and effector subpopulations of the preterminally differentiated (TEM) and terminally differentiated (TEMRA) memory T-cells was studied. AFP was found to prevent the conversion of naive T-helpers into effector subpopulations of memory T cells (TEM and TEMRA) while reducing the total production of IL-4 and IFN-ã by the studied cell populations. The data reveal a new role of AFP in the immune tolerance formation during pregnancy. Доп.точки доступа: Zamorina, S. A.; Timganova, V. P.; Bochkova, M. S.; Khramtsov, P. V.; Fomicheva, K. A.; Rayev, M. B.; Chereshnev, V. A.