Вид документа : Статья из журнала Шифр издания : 57/A 41 Автор(ы) : Chereshnev V. A., Rodionov S. Yu., Vasilyev N. V., Orlov O. A., Cherkassov V. A. Заглавие : Alpha-fetoprotein immunotherapy as a stage of combined treatment of cancer patients Место публикации : Voprosy Onkologii . - 2005. - Vol.51, №1. - С. 86-92 ББК : 57 Предметные рубрики: БИОЛОГИЧЕСКИЕ НАУКИ Ключевые слова (''Своб.индексиров.''): alpha fetoprotein--antibody--apoptosis Аннотация: The paper discusses the preliminary findings on alpha-feto-protein (AFP) treatment of 58 patients with stage III-IV malignancies of different localizations.influence on neoplastic processes was registered in poorly differentiated cell tumors, nor were any immunological mechanisms of antitumor action triggered on. However, in moderately- and well-differentiated cell tumors, several foci of acute immune inflammation were induced. It is suggested that AFP is responsible for tumor cell apoptosis by freeing antigenic determinants from shielding antibodies via elimination of «immunological enhancement» of tumor growth. Доп.точки доступа: Chereshnev, V. A.; Rodionov, S. Yu.; Vasilyev, N. V.; Orlov, O. A.; Cherkassov, V. A.