S 98 Synthesis and anti-tuberculous activity of diesters based on isosteviol and dicarboxylic acids [Electronic resource] / V. E. Kataev, O. I. Militsina, I. Yu. Strobykina, G. I. Kovylyaeva, R. Z. Musin, O. V. Fedorova, G. L. Rusinov, M. N. Zueva, G. G. Mordovskoi, A. G. Tolstikov // Pharmaceutical Chemistry Journal. - 2006. - Vol. 40, № 9. - P473-475. - Библиогр. : с. 475 (17 назв.) Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: Diesters based on isosteviol and dicarboxylic acids were synthesized and tested for antituberculous activity. Isosteviol and some of its derivatives exhibit appreciable tuberculostatic properties in vitro, the activity being dependent on the length of the polymethylene spacer connecting two ent-beyeran fragments. The mechanism of the antituberculous action of isosteviol derivatives are discussed. \\\\Expert2\\nbo\\Pharmaceutical Chemistry Journal\\2006, 40 (9), 473.pdf |