A 89 Asymmetric induction in the reactions of 3-aryl-1,2,4-triazin-5(4H)-ones with C-nucleophiles [Electronic resource] / I. N. Egorov, G. V. Zyryanov, E. N. Ulomskii, V. L. Rusinov, O. N. Chupakhin // Tetrahedron Letters. - 2006. - Vol. 47, № 42. - P7485-7487 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: 3-Aryl-1,2,4-triazin-5(4H)-ones, in the presence of N-protected amino acids, react with C-nucleophiles to form 1-acyl-6-Nu-3-aryl-1,6-dihydro-1,2,4-triazin-5(4H)-ones in high diastereomeric excess. This is the first case of the use of amino acids as chiral auxiliaries in nucleophilic additions to triazinones. \\\\Expert2\\nbo\\Tetrahedron Letters\\2006, v. 47, p.7485.pdf |