S 90 Study of the effect of the nature of the side chain in esters of amino acids on the diastereoselectivity of condensation with 5(4H)-oxazolone in the synthesis of dipeptides with N-terminal N-acetylphenylalanine [Electronic resource] / V. P. Krasnov, E. A. Zhdanova, N. Z. Solieva, L. Sh. Sadretdinova, I. M. Bukrina, A. M. Demin, G. L. Levit, M. A. Ezhikova, M. I. Kodess // Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya). - 2004. - Vol. 53, № 6. - P1331-1334 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: Conditions for fast racemization of 5(4H)-oxazolones prepared from N-acylphenylalanine were found. Reactions of 4-benzyl-2-methyl-5(4H)-oxazolone with amino acid esters proceed diastereoselectively to give predominantly dipeptides comprising R-phenylalanine. The diastereoselectivity increases with complication of the structure of the side chain in the amino acid esters \\\\Expert2\\nbo\\Russian Chemical Bulletin\\2004, 53 (6), 1331.pdf |