A 10 A new approach to the synthesis of lamotrigine and other 3,5-diamino-1,2,4-triazine derivatives [Electronic resource] / E. N. Ulomskii, T. S. Shestakova, S. L. Deev, V. L. Rusinov, O. N. Chupakhin // Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya). - 2005. - Vol. 54, № 3. - P726-732 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: A new in principle method for the synthesis of 6-aryl(hetaryl)-3,5-diamino-1,2,4-triazines by decomposition of pre-synthesized tetrazolo[1,5-b][1,2,4]triazines was developed. The advantages of this method over traditional methods were demonstrated using the synthesis of a modern antiepileptic preparation lamotrigine, as an example \\\\Expert2\\nbo\\Russian Chemical Bulletin\\2005, 54 (3), 726.pdf |