K 79 Kovalev, I. S. Reaction of 2-pyridyllithium with azine N-oxides. Simple and convenient method for the synthesis of 2,2-bipyridine 1-oxide and 2,2:6,2:62-tetrapyridine 1-oxide [Electronic resource] / I. S. Kovalev, V. L. Rusinov, O. N. Chupakhin // Chemistry of Heterocyclic Compounds. - 2009. - Vol. 45, № 2. - P176-181 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: In the reaction of 2-pyridyllithium with quinoline 1-oxide and isoquinoline 2-oxide a nucleophilic substitution of hydrogen occurs to form the corresponding pyridin-2-ylquinolines. A dimerization of the substrate occurs with pyridine 1-oxide, 2,2-bipyridine 1-oxide or quinoxaline N-oxide. A similar dimerization in good yield occurs when treating azine N-oxides with tert-butyllithium and this serves as a simple and convenient method for preparing bi- and tetrapyridines \\\\Expert2\\nbo\\Chemistry of Heterocyclic Compounds\\2009, v.45, N 2, p.176.pdf |