A 20 Adamantylation of 3-nitro- and 3-ethoxycarbonyl-1,2,4-triazolo[5,1-c]-1,2,4-triazin-4-ones [Electronic resource] / E. N. Ulomskii, S. L. Deev, A. V. Tkachev, I. K. Moiseev, V. L. Rusinov // Russian Journal of Organic Chemistry (Translation of Zhurnal Organicheskoi Khimii). - 2002. - Vol. 38, № 2. - P272-280. - Bibliogr. : p. 280 (15 ref.) Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): ADAMANTANE DERIVATIVE -- SULFURIC ACID -- TRIAZINE DERIVATIVE -- UNCLASSIFIED DRUG Аннотация: Reaction of 3-nitro- and 3-ethoxycarbonyl-1,2,4-triazolo[5,1-c]-1,2,4-triazin-4-ones with 1-adamantanol (or 1-adamantyl nitrate) in concentrated sulfuric acid or with 1-bromoadamantane in sulfolane affords N-adamantyl derivatives. The adamantylation of 3-nitro-1,4-dihydro-7H-1,2,4-triazolo[5,1-c]-1,2,4-triazin-4-one yields a mixture of N8- and N1-isomers that undergo interconversion in concentrated sulfuric acid along intermolecular mechanism. \\\\Expert2\\nbo\\Russian Journal of Organic Chemistry\\2002, 38 (2), 272.pdf |