Metal-free, Phl(OAc)2-promoted oxidative C(sp2)−H difunctionalization: synthesis of thioaminated naphthoquinones / S. Pal, R. Chatterjee, S. Santra [et al.] // Advanced synthesis and catalysis. - 2021. - Vol. 363, № 23. - P5300–5309 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): OXIDATIVE COUPLING -- PIDA -- NAPTHTHOQUINONE -- THIOAMINATION Аннотация: A three-component thioamination reactionhas been developedin the presenceof phenyliodonium(III) diacetate(PIDA)leadingto the formationof a thioaminated products.This catalytic approach represents a method for the metal-freethioamination of 1,4-naphthoquinone. It was observed that maleimides also works moothly under this metal-free reaction condition. This present method implies the oxidative coupl in greaction through a one-stepprocess with the generationof CN and CS bonds.Various aromaticand aliphaticthiolsand amines provided the correspond ingthioaminated compounds in 62–88% yields.A plausiblere action path way has been predicted according to few control experiments. |