Вид документа : Статья из журнала Шифр издания : 54/S 98 Автор(ы) : Fokin A. S., Burgart Ya. V., Saloutin V. I., Chupakhin O. N. Заглавие : Synthesis of 2-(1-alkyl(aryl)-4-oxo-5,6,7,8-tetrafluoro-1,4-dihydroquinolin-3-yl)glyoxylic acid derivatives Место публикации : Journal of Fluorine Chemistry. - 2001. - Vol. 108, № 2. - С. 187-194 ББК : 54 Предметные рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: Methods for synthesis of previously unknown 2-(1-alkyl(aryl)-4-oxo-5,6,7,8-tetrafluoro-1,4-dihydroquinolin-3-yl)glyoxylic acids and their esters from the copper chelate of ethyl pentafluorobenzoylpyruvate were developed. 1-Aryl(alkyl)-3-ethoxalyl-5,6,7,8-tetrafluoro-quinolin-4-ones react with o-phenylenediamine and o-aminophenol to give the corresponding quinolin-3-ylquinoxalones and quinolin-3-ylbenzoxazines. The same heterocycles act with o-aminothiophenol to yield ethyl-2-(7-(2-aminophenylthio)-1-aryl-5,6,8-trifluoro-quinolon-3-yl)-2-(2-mercaptophenylimino)glioxylates. Interaction of 1-aryl-3-ethoxalyl-(heteryl)-5,6,7,8-tetrafluoroquinolones with morpholine gives 7-mono- and 5,7-disubstituted products depending on the reaction conditions???? Держатели документа: Центральная научная библиотека УрО РАН Доп.точки доступа: Fokin, A. S.; Фокин Андрей Сергеевич; Burgart, Ya. V.; Бургарт Янина Валерьевна; Saloutin, V. I.; Chupakhin, O. N.