Вид документа : Статья из журнала Шифр издания : 54/S 73 Автор(ы) : Sosnovskikh V. Ya., Irgashev R. A., Kodess M. I. Заглавие : One-pot three-component reaction of 3-(polyfluoroacyl)chromones with active methylene compounds and ammonium acetate: regioselective synthesis of novel RF-containing nicotinic acid derivatives Место публикации : Tetrahedron. - 2008. - Vol. 64, № 13. - С. 2997-3004 ББК : 54 Предметные рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: Reactions of 3-(polyfluoroacyl)chromones with acetoacetamide and ethyl acetoacetate in the presence of ammonium acetate proceed at the C-2 atom of the chromone system with pyrone ring-opening and subsequent cyclization to 5-salicyloyl-2-methyl-6-(trifluoromethyl)nicotinamides, ethyl 5-salicyloyl-2-methyl-6-(trifluoromethyl)nicotinates, and ethyl 5-hydroxy-2-methyl-5-(polyfluoroalkyl)-5H-chromeno[4,3-b]pyridine-3-carboxylates. Similar reaction with ?-aminocrotononitrile gave 5-hydroxy-2-methyl-5-(polyfluoroalkyl)-5H-chromeno[4,3-b]pyridine-3-carbonitriles???? Держатели документа: Центральная научная библиотека УрО РАН Доп.точки доступа: Irgashev, R. A.; Kodess, M. I.; Кодесс Михаил Исаакович