Вид документа : Статья из журнала Шифр издания : 54/P 80 Автор(ы) : Saloutina L. V., Zapevalov A. Ya., Kodess M. I., Saloutin V. I., Aleksandrov G. G., Chupakhin O. N. Заглавие : Polyfluoro-2,3-epoxyalkanes in reactions with thiourea and thiosemicarbazide Место публикации : Russian Journal of Organic Chemistry (Translation of Zhurnal Organicheskoi Khimii). - 2000. - Vol. 36, № 6. - С. 887-899 Примечания : Bibliogr. : p. 899 (17 ref.) ББК : 54 Предметные рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: Reactions of polyfluoro-2,3-epoxyalkanes with thiourea and thiosemicarbazide afforded 2-amino-4-hydroxy-4,5-di(polyfluoroalkyl)-5-fluoro-1,3-thiazolines and 2-hydrazino-4-hydroxy-4,5-di(polyfluoroalkyl)-5-fluoro-1,3-thiazolines respectively. Unsymmetrical oxiranes furnish mixtures of regioisomeric heterocyclic compounds, and the epoxy cycle is predominantly cleaved from the side of bulkier fluoroalkyl group. The reactions of E-oxiranes are stereospecific and provide 1,3-thiazolines in the E-form. The structure of compounds obtained was confirmed by IR, 19F, 1H, and 13C NMR spectroscopy, by mass spectra and chemical transformations. E-isomers of 2-amino-4-hydroxy-4,5-bis(trifluoromethyl)-5-fluoro-1,3-thiazoline and 2-amino-5-heptafluoropropyl-4-hydroxy-4-trifluoromethyl-5-fluoro-1,3-thiazoline were subjected to X-ray diffraction analysis. Держатели документа: Центральная научная библиотека УрО РАН Доп.точки доступа: Saloutina, L. V.; Салоутина Людмила Васильевна; Zapevalov, A. Ya.; Запевалов Александр Яковлевич; Kodess, M. I.; Кодесс Михаил Исаакович; Saloutin, V. I.; Aleksandrov, G. G.; Chupakhin, O. N.