Вид документа : Статья из журнала Шифр издания : 54/S 98 Автор(ы) : Glushkov V. A., Stryapunina O. G., Gorbunov A. A., Maiorova O. A., Slepukhin P. A., Ryabukhina S. Ya., Khorosheva E. V., Sokol V. I., Shklyaev Yu. V. Заглавие : Synthesis of 1-substituted 2-azaspiro[4.5]deca-6,9-diene-8-ones and 2-azaspiro[4.5]deca-1,6,9-triene-8-ones by a three-component condensation of 1,2,3-, 1,2,4- or 1,3,5-trimethoxybenzene with isobutyric aldehyde and nitriles Место публикации : Tetrahedron. - 2010. - Vol. 66, № 3. - С. 721-729 ББК : 54 Предметные рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: A three-component condensation of 1,2,3- or 1,2,4-trimethoxybenzene with isobutyric aldehyde and alkyl cyanoacetates in the presence of sulfuric acid resulted in the formation of substituted 2-azaspiro[4.5]deca-6,9-diene-8-ones. The same reaction of aromatic nitriles yielded 2-azaspiro[4.5]deca-1,6,9-triene-8-ones; in the case of 1,2,3-trimethoxybenzene corresponding Ritter amides were also observed. The condensation of 1,3,5-trimethoxybenzene with isobutyric aldehyde and alkyl cyanoacetates provided the compounds of the formal Knoevenagel condensation Держатели документа: Центральная научная библиотека УрО РАН Доп.точки доступа: Glushkov, V. A.; Stryapunina, O. G.; Gorbunov, A. A.; Maiorova, O. A.; Slepukhin, P. A.; Ryabukhina, S. Ya.; Khorosheva, E. V.; Sokol, V. I.; Shklyaev, Yu. V.