Вид документа : Статья из журнала Шифр издания : 54/G 65 Автор(ы) : Goryaeva M. V., Burgart Ya. V., Saloutin V. I. Заглавие : Synthesis of pyrimido[1,2-alfa]benzimidazoles from ethyl 2-ethoxymethylidene-3-oxo-3-(polyfluoroalkyl)propionates [Electronic resource] Место публикации : Russian Journal of Organic Chemistry (Translation of Zhurnal Organicheskoi Khimii). - 2010. - Vol. 46, № 3. - С. 432-438: рис., табл. Систем. требования: http://www.springerlink.com/content/92054610666232j2/fulltext.pdf Примечания : Bibliogr. : p. 438 (22 ref.). - 1.11.2011 г. ББК : 54 Предметные рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: Cyclization of ethyl 2-ethoxymethylidene-3-oxo-3-polyfluoroalkylpropionates with benzimidazol-2-amine in boiling 1,4-dioxane followed two concurrent pathways with participation of fluoroacyl and ethoxycarbonyl fragments and formation of, respectively, ethyl 4-hydroxy-4-polyfluoroalkyl-1,4-dihydropyrimido-[1,2-alfa]benzimidazole-3-carboxylates and 3-polyfluoroacylpyrimido[1,2-alfa]benzimidazol-4-ols. Dihydropyrimido[1,2-alfabenzimidazole derivatives undergo dehydration to give ethyl 4-(polyfluoroalkyl)pyrimido[1,2-alfa]benzimidazole-3-carboxylates, whereas the hydroxy group in 3-polyfluoroacylpyrimido[1,2-a]benzimidazol-4-ols is capable of being replaced by the amino group of the second benzimidazole molecule with formation of 4-(1H-benzimidazol-2-ylamino)-3-polyfluoroacylpyrimido[1,2-alfa]benzimidazoles. Держатели документа: Центральная научная библиотека УрО РАН Доп.точки доступа: Burgart, Ya. V.; Бургарт Янина Валерьевна; Saloutin, V. I.