Вид документа : Статья из журнала Шифр издания : 54/F 33 Автор(ы) : Bazhin D. N., Shchegol'kov E. V., Kudyakova Yu.S., Scherbakov K. V., Burgart Ya. V., Saloutin V. I. Заглавие : Features of synthesis and structure of ethyl (2Z)-3-hydroxy-(2,3,4,5-tetrafluorophenyl)-propyl-2-enoate Место публикации : Russian Journal of General Chemistry. - 2012. - Vol. 82, № 1. - С. 116-121 Примечания : Bibliogr. : p. 121 (22 ref.) ББК : 54 Предметные рубрики: ХИМИЧЕСКИЕ НАУКИ Ключевые слова (''Своб.индексиров.''): antibacterial agents--derivatives--ofloxacin--esters Аннотация: The structure of key intermediates in the synthesis of fluoroquinolone antibiotics: diethyl (2,3,4,5-tetrafluorobenzoyl)malonate and ethyl (2Z)-3-hydroxy-(2,3,4,5-tetrafluorophenyl)prop-2-enoate was for first time studied using X-ray diffraction (XRD) and H-1, F-19 NMR spectroscopy. In solution both the esters were shown to exist as a mixture of enol and ketone tautomeric forms with predominance of the latter. According to the XRD analysis, ethyl (2Z)-3-hydroxy-(2,3,4,5-tetrafluorophenyl)prop-2-enoate in the solid state exists entirely in the enol form Держатели документа: Центральная научная библиотека УрО РАН Доп.точки доступа: Bazhin, D. N.; Shchegol'kov, E. V.; Kudyakova, Yu.S.; Scherbakov, K. V.; Burgart, Ya. V.; Бургарт Янина Валерьевна; Saloutin, V. I.