Вид документа : Шифр издания : 54/R 30 Автор(ы) : Tolshchina S. G., Ishmetova R. I., Ignatenko N. K., Korotina A. V., Ganebnuikh I. N., Ol'shevskaya V. A., Kalinin V. N., Rusinov G. L. Заглавие : Reactions of 1,2,4,5-tetrazines with S-nuc Место публикации : Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya). - 2011. - Vol.60, №5. - С. 985-991 ББК : 54 Предметные рубрики: ХИМИЧЕСКИЕ НАУКИ Ключевые слова (''Своб.индексиров.''): 1,2,4,5-tetrazines --heterocyclic leaving groups --tetrazines Аннотация: The reactions of 3,6-disubstituted and azoloannulated 1,2,4,5-tetrazines containing heterocyclic leaving groups with S-nucleophiles were studied. The methods of introduction of functionalized thiols, including thiol derivatives of 1,7- and 1,2-dicarba-closo-dodecaboranes, into the tetrazine ring were developed. It was established for the first time that, instead of replacement of a leaving group in the tetrazine ring, the attack of S-nucleophile at the unsubstituted carbon atom occurs in the case of imidazo[1,2-b][1,2,4,5]tetrazines to form previously unknown products of nucleophilic substitution of the hydrogen atom Доп.точки доступа: Tolshchina, S. G.; Ishmetova, R. I.; Ишметова Рашида Иршотовна; Ignatenko, N. K.; Игнатенко Нина Константиновна; Korotina, A. V.; Ganebnuikh, I. N.; Ганебных Илья Николаевич; Ol'shevskaya, V. A.; Kalinin, V. N.; Rusinov, G. L.; Русинов Геннадий Леонидович