Вид документа :
Шифр издания : 54/O-57
Автор(ы) : Rozhkova Y. S., Galata K. A., Gorbunov A. A., Shklyaev Yu. V., Ezhikova M. A., Kodess M. I.
Заглавие : One-Pot, Three-Component Synthesis of Novel Pyrroloacridinones via Intramolecular ipso Dearomatization–Intramolecular Aza-Michael Addition Sequence
Место публикации : Synlett. - 2014. - Vol. 25, № 18. - С. 2617-2623
ББК : 54
Предметные рубрики: ХИМИЧЕСКИЕ НАУКИ
Ключевые слова (''Своб.индексиров.''): intramolecular ipso dearomatization--spiro-substituted cyclohexa-2,5-dienone--domino reaction
Аннотация: A one-pot, three-component synthesis of novel pyrroloacridinones from a set of alkoxy arenes and 2,6-dialkylphenols, isobutyric aldehyde, and 2-aminobenzonitrile is described. We have demonstrated the efficacy of the combination of intramolecular electrophilic ipso dearomatization of suitable aromatic compounds leading to spiro-substituted cyclohexa-2,5-dienones and intramolecular aza-Michael addition for the preparation of complex aza-heterocyclic systems.

Доп.точки доступа:
Rozhkova, Y. S.; Galata, K. A.; Gorbunov, A. A.; Shklyaev, Yu. V.; Ezhikova, M. A.; Kodess, M. I.; Кодесс Михаил Исаакович