Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Savateev K. V., Borisov S. S., Voinkov E. K., Ulomskii E. N., Rusinov V. L., Chupakhin O. N.
Заглавие : 6-Aminotriazolo[1,5-a]pyrimidines as precursors of 1,2,4-triazolo[5,1-b]purines [Электронный ресурс]
Место публикации : Chimica Techno Acta. - 2015. - Vol. 2, № 2. - С. 127-128
Систем. требования: http://elibrary.ru/item.asp?id=23785871
Примечания : Bibliogr. : p. 128 (2 ref.). - 2.12.15
Аннотация: Triazolo[5,1-b]purines are rare structural analogues of natural nucleosides and nucleobases purine series. At the same time, prominent representatives of azolopurines exhibit a broad spectrum of antiviral effect, activity against of rheumatoid arthritis, psoriasis, Alzheimer’s, Parkinson’s and etc. Despite the practical value azolo[5,1-b]purines extremely sparingly represented in the chemical literature, due to the complexity of their synthesis. We suggest a convenient way to synthesize triazolopurines with aminotriazolo[1,5-a]pyrimidines (2) as available starting compounds obtained in good yield by reduction of nitro derivatives (1).

Доп.точки доступа:
Savateev, K. V.; Borisov, S. S.; Voinkov, E. K.; Ulomskii, E. N.; Rusinov, V. L.; Chupakhin, O. N.