Вид документа : Статья из журнала Шифр издания : 54/A 10 Автор(ы) : Bazhin D. N., Kudyakova Yu.S., Roeschenthaler G.-V., Burgart Ya. V., Slepukhin P. A., Isenov M. L., Saloutin V. I., Charushin V. N. Заглавие : A Convenient Approach to CF3-Containing N-Heterocycles Based on 2-Methoxy-2-methyl-5-(trifluoromethyl)furan-3(2H)-one [Электронный ресурс] Место публикации : European Journal of Organic Chemistry. - 2015. - № 23. - С. 5236-5245 Систем. требования: http://apps.webofknowledge.com/ Примечания : Bibliogr. : p. 5245 (23 ref.). - 18.01.16 ББК : 54 Предметные рубрики: ХИМИЧЕСКИЕ НАУКИ Ключевые слова (''Своб.индексиров.''): nitrogen heterocycles --fluorine--oxygen heterocycles Аннотация: New synthetic routes to trifluoromethylated N-heterocycles based on condensations of 2-methoxy-2-methyl-5-(trifluoromethyl)furan-3(2H)-one with bifunctional N-nucleophiles are described. For the first time, trifluoromethyl-containing pyrazoles, pyrazolines and isoxazolines bearing hydrazone or oxime groups could be obtained by a one-pot strategy based on reactions of 5-(trifluoromethyl)furan-3(2H)-one with two equivalents of the corresponding hydrazines or hydroxylamine in the presence of an acid. The interaction of furan-3(2H)-one with ureas proceeded under mild conditions to furnish 1H-furo[2,3-d]imidazol-2(3H)-one derivatives in good yield. Further, a trifluoromethyl-containing quinoxaline derivative was obtained by condensation of furan-3(2H)-one with ortho-phenylenediamine. Доп.точки доступа: Bazhin, D. N.; Kudyakova, Yu.S.; Roeschenthaler, G.-V.; Burgart, Ya. V.; Бургарт Янина Валерьевна; Slepukhin, P. A.; Isenov, M. L.; Saloutin, V. I.; Charushin, V. N.