Вид документа : Статья из журнала Шифр издания : 54/A 10 Автор(ы) : Irgashev R. A., Karmatsky A. A., Rusinov G. L., Charushin V. N. Заглавие : A new and convenient synthetic way to 2-substituted thieno[2,3-b]indoles [Электронный ресурс] Место публикации : Beilstein Journal of Organic Chemistry. - 2015. - Vol. 11. - С. 1000-1007 Систем. требования: http://apps.webofknowledge.com/ Примечания : Bibliogr. : p. 1006-1007 (35 ref.). - 18.01.2016 ББК : 54 Предметные рубрики: ХИМИЧЕСКИЕ НАУКИ Ключевые слова (''Своб.индексиров.''): aldol-crotonic condensation --lawesson's reagent--isatin Аннотация: A short and robust approach for the synthesis of 2-(hetero)aryl substituted thieno[2,3-b]indoles from easily available 1-alkylisatins and acetylated (hetero)arenes has been advanced. The two-step procedure includes the "aldol-crotonic" type of condensation of the starting materials, followed by treatment of the intermediate 3-(2-oxo-2-(hetero)arylethylidene) indolin-2-ones with Lawesson's reagent. The latter process involves two sequential reactions, namely reduction of the C=C ethylidene double bond of the intermediate indolin-2-ones followed by the Paal-Knorr cyclization, thus affording tricyclic thieno[2,3-b]indoles. Доп.точки доступа: Irgashev, R. A.; Karmatsky, A. A.; Rusinov, G. L.; Русинов Геннадий Леонидович; Charushin, V. N.