Вид документа : Статья из журнала Шифр издания : Г/S 98 Автор(ы) : Vozdvizhenskaya O. A., Andronova V. L., Galegov G. A., Levit G. L., Krasnov V. P., Charushin V. N. Заглавие : Synthesis and antiherpetic activity of novel purine conjugates with 7,8-difluoro-3-methyl-3,4-dihydro-2H-1,4-benzoxazine Место публикации : Chemistry of Heterocyclic Compounds. - 2021. - Vol. 57, № 4. - С. 490–497 ББК : Г Предметные рубрики: ХИМИЧЕСКИЕ НАУКИ Ключевые слова (''Своб.индексиров.''): 6-chloropurine--antiviral activity--herpes simplex virus type 1 Аннотация: A method for the synthesis of novel purine conjugates with 7,8-difluoro-3-methyl-3,4-dihydro-2H-1,4-benzoxazine containing fragments of ω-amino acids with different lengths of the polymethylene chain as a linker has been developed. It was found in experiments in vitro that the obtained compounds are active against the herpes simplex virus type 1, including the acyclovir-resistant strain. Доп.точки доступа: Vozdvizhenskaya, O. A.; Andronova, V. L.; Galegov, G. A.; Levit, G. L.; Левит Галина Львовна; Krasnov, V. P.; Charushin, V. N.