Вид документа : Статья из журнала Шифр издания : Г/O-97 Автор(ы) : Lyapustin D. N., Ulomsky E. N., Rusinov V. L., Chupakhin O. N., Shchepochkin A. V., Balyakin I. A. Заглавие : Oxidative aromatization of 4,7-dihydro-6-nitroazolo[1,5-a] pyrimidines: synthetic possibilities and limitations, mechanism of destruction, and the theoretical and experimental substantiation Место публикации : Molecules. - 2021. - Vol. 26, № 16. - Ст.4719 ББК : Г Предметные рубрики: ХИМИЧЕСКИЕ НАУКИ Ключевые слова (''Своб.индексиров.''): azolo[1,5-a]pyrimidines--nitro-synthons--oxidation--oxidative destruction--synthesis of heterocycles--nitro compounds Аннотация: The reaction tolerance of the multicomponent process between 3-aminoazoles, 1-morpholino-2-nitroalkenes, and aldehydes was studied. The main patterns of this reaction have been established. Conditions for the oxidation of 4,7-dihydro-6-nitroazolo[1,5-a]pyrimidines were selected. Previous claims that the 4,7-dihydro-6-nitroazolo[1,5-a]pyrimidines could not be aromatised have now been refuted. Compounds with an electron-donor substituent at position seven undergo decomposition during oxidation. The phenomenon was explained based on experimental data, electro-chemical experiment, and quantum-chemical calculation. The mechanism of oxidative degradation has been proposed. Доп.точки доступа: Lyapustin, D. N.; Ulomsky, E. N.; Rusinov, V. L.; Chupakhin, O. N.; Shchepochkin, A. V.; Balyakin, I. A.