Вид документа : Статья из журнала Шифр издания : 54/S 70 Автор(ы) : Kopchuk D. S., Chepchugov N. V., Kovalev I. S., Santra S., Rahman M., Zyryanov G. V., Charushin V. N., Chupakhin O. N., Giri K., Majee A. Заглавие : Solvent-free synthesis of 5-(aryl/alkyl)amino-1,2,4-triazines and α-arylamino-2,2′-bipyridines with greener prospects Место публикации : RSC Advances. - 2017. - Vol. 7, № 16. - С. 9610-9619 ББК : 54 Предметные рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: A green and highly efficient method has been developed for the synthesis of 5-(aryl/alkyl)amino-1,2,4-triazines and a-arylamino-2,20-bipyridines according to the principles of atom economy. It has been performed by two consecutive solvent-free reaction pathways: the ipso-substitution of a cyano-group in 5-cyano-1,2,4-triazines and the aza-Diels-Alder reaction of the resulting 5-arylamino-1,2,4-triazines with 1-morpholinocyclopentene used as a dienophile. Solvent and catalyst-free conditions, operational simplicity, the compatibility with various functional groups, nonchromatographic purification technique, and high yields are the notable advantages of this procedure. The present methodology possesses a low E-factor. Доп.точки доступа: Kopchuk, D. S.; Chepchugov, N. V.; Kovalev, I. S.; Santra, S.; Rahman, M.; Zyryanov, G. V.; Charushin, V. N.; Chupakhin, O. N.; Giri, K.; Majee, A.