Вид документа : Статья из журнала Шифр издания : Автор(ы) : Ishmetova R. I., Belyaninova I. A., Ignatenko A. V., Rusinov G. L., Chupakhin O. N., Charushin V. N., Gerasimova N. A., Evstigneeva N. P., Zil’berberg N. V., Kungurov N. V., Mukhina A. A. Заглавие : Synthesis and antibacterial and antifungal activity of 3-(azol-1-yl)-6-r-1,2,4,5-tetrazines Место публикации : Pharmaceutical chemistry journal. - 2020. - Vol. 53, № 10. - С. 899-904 Предметные рубрики: ХИМИЧЕСКИЕ НАУКИ Ключевые слова (''Своб.индексиров.''): 1,2,4,5-tetrazines--1,3-dipolar cycloaddition-- nucleophilic substitution--antibacterial and antifungal activity Аннотация: Nucleophilic substitution and 1,3-dipolar cycloaddition reactions were used to synthesize 3,6-disubstituted derivatives of simm-tetrazine containing azolyl, aminoalkyl, and oxyalkyl fragments. The antibacterial activity of the resulting compounds was studied using the obligate pathogen Neisseria gonorrhoeae and opportunistic pathogenic microorganisms, while antifungal activity was assessed using anthropo- and zooanthropophilic dermatophytes. Доп.точки доступа: Ishmetova, R. I.; Ишметова Рашида Иршотовна; Belyaninova, I. A.; Ignatenko, A. V.; Rusinov, G. L.; Chupakhin, O. N.; Charushin, V. N.; Gerasimova, N. A.; Evstigneeva, N. P.; Zil’berberg, N. V.; Kungurov, N. V.; Mukhina, A. A.