Вид документа : Статья из журнала Шифр издания : Г/R 43 Автор(ы) : Verbitskiy E. V., Baskakova S. A., Belyaev D. V., Rusinov G. L., Charushin V. N., Vakhrusheva D. V., Eremeeva N. I. Заглавие : Renaissance of 4-(5-nitrofuran-2-yl)-5-arylamino substituted pyrimidines: microwave-assisted synthesis and antitubercular activity Место публикации : Mendeleev Communications. - 2021. - Vol. 31, № 2. - С. 210-212 ББК : Г Предметные рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: The Buchwald–Hartwig cross-coupling of 5-bromo-4-(furan-2-yl)pyrimidine with various anilines afforded the corresponding new 5-(arylamino)pyrimidines, the reaction being accelerated by microwave irradiation. Most of the obtained compounds proved to possess a high bacteriostatic in vitro effect against Mycobacterium tuberculosis H37Rv, Neisseria gonorrhoeae, and Staphylococcus aureus including Methicillin-resistant strain, which is stronger than that of the commercial drug Spectinomycin. Доп.точки доступа: Verbitskiy, E. V.; Baskakova, S. A.; Belyaev, D. V.; Rusinov, G. L.; Русинов Геннадий Леонидович; Charushin, V. N.; Vakhrusheva, D. V.; Eremeeva, N. I.