Вид документа : Статья из журнала Шифр издания : Автор(ы) : Artem'ev G. A., Rusinov V. L., Kopchuk D. S., Savchuk M. I., Ulomsky E. N., Zyryanov G. V., Charushin V. N., Chupakhin O. N., Santra S., Majee A., Du W. Заглавие : Synthetic approaches to 1,2,4-triazolo[5,1-c][1,2,4]triazin-7-ones as basic heterocyclic structures of the antiviral drug Riamilovir (“Triazavirin®”) active against SARS-CoV-2 (COVID-19) Место публикации : Organic & biomolecular chemistry. - 2022. - Vol. 20, № 9. - С. 1828-1837 Предметные рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ Аннотация: Fragments of 1,2,4-triazolo[5,1-c][1,2,4]triazin-7-one are found in many compounds with various types of biological activities, including the antiviral drug Riamilovir (Triazavirin®), which shows activity against SARS-CoV-2 (COVID-19). Therefore, the development of convenient methods for the synthesis of new derivatives of 1,2,4-triazolo[5,1-c][1,2,4]triazin-7-one is always in demand. This review systematizes the information on the most common synthetic methods for constructing the 1,2,4-triazolo[5,1-c][1,2,4]triazin-7-one heterocyclic system. Доп.точки доступа: Artem'ev, G. A.; Rusinov, V. L.; Kopchuk, D. S.; Savchuk, M. I.; Ulomsky, E. N.; Zyryanov, G. V.; Charushin, V. N.; Chupakhin, O. N.; Santra, S.; Majee, A.; Du, W.