Вид документа : Статья из журнала Шифр издания : 54/A 10 Автор(ы) : Layeva A. A., Nosova E. V., Lipunova G. N., Trashakhova T. V., Charushin V. N. Заглавие : A new approach to fluorinated 4(1H)-quinazolinones Место публикации : Journal of Fluorine Chemistry. - 2007. - Vol. 128, № 7. - С. 748-754 ББК : 54 Предметные рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: A new approach for the synthesis of fluorinated 1H-quinazolin-4-ones and 4-substituted quinazolines has been developed. 6-Fluoro-1H-quinazolin-4-ones were obtained by intramolecular cyclization of fluorine-containing S-ethyl N-benzoylisothioureas. Nucleophilic substitution reactions at positions 2 and 7, as well as alkylation at 1-position of quinazolinones were investigated. In addition, the synthesis of fluorine-containing 4-aminoquinazolines was carried out. Держатели документа: Центральная научная библиотека УрО РАН Доп.точки доступа: Layeva, A. A.; Nosova, E. V.; Lipunova, G. N.; Trashakhova, T. V.; Charushin, V. N.