Вид документа : Статья из журнала Шифр издания : 54/A 89 Автор(ы) : Fedorova O. V., Titova Yu. A., Vigorov A. Yu., Toropova M. S., Alisienok O. A., Murashkevich A., Krasnov V. P., Rusinov G. L., Charushin V. N. Заглавие : Asymmetric Biginelli Reaction Catalyzed by Silicon, Titanium and Aluminum Oxides Место публикации : Catalysis Letters. - 2016. - Vol.146, № 2. - С. 493-498 ББК : 54 Предметные рубрики: ХИМИЧЕСКИЕ НАУКИ Ключевые слова (''Своб.индексиров.''): biginelli reaction --phenylethylamine --aluminum oxides Аннотация: The asym. Biginelli reaction was investigated in the presence of N-​[(2S,​4R)​-​4-​hydroxyprolyl]​-​(S)​-​1-​phenylethylamine as chiral inducer and silicon, titanium or aluminum oxides (individual and mixed, bulk and nanosized) as heterogeneous catalysts. The synthesis of Et (4R)​-​6-​methyl-​2-​oxo-​4-​phenyl-​1,​2,​3,​4-​tetrahydropyrimidine-​5-​carboxylate from benzaldehyde, urea and Et acetoacetate has been described. It has been shown that all studied oxides improve chemo- and stereoselectivity of the Biginelli reaction. Доп.точки доступа: Fedorova, O. V.; Федорова Ольга Васильевна; Titova, Yu. A.; Vigorov, A. Yu.; Toropova, M. S.; Alisienok, O. A.; Murashkevich, A.; Krasnov, V. P.; Rusinov, G. L.; Charushin, V. N.