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 Найдено в других БД:Каталог книг и продолжающихся изданий (1559)Сводный каталог иностранных периодических изданий, имеющихся в библиотеках УрО РАН (10)Каталог диссертаций и авторефератов диссертаций УрО РАН (185)Каталог препринтов УрО РАН (1975 г. - ) (22)Публикации об УрО РАН (1)Изобретения уральских ученых (1)Интеллектуальная собственность (статьи из периодики) (5)Нанотехнологии (90)Труды Института высокотемпературной электрохимии УрО РАН (195)Труды Института истории и археологии УрО РАН (34)Труды сотрудников Института горного дела УрО РАН (1)Труды сотрудников Института органического синтеза УрО РАН (214)Труды сотрудников Института теплофизики УрО РАН (16)Труды сотрудников Института химии твердого тела УрО РАН (396)Расплавы (848)Публикации Чарушина В.Н. (82)Каталог библиотеки ИЭРиЖ УрО РАН (44)
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1.
Инвентарный номер: нет.
   


   
    1,3,4-thiadiazine derivates – antioxidants and protein glycation blockers – for correction of experimental diabetes mellitus / V. V. Emelyanov, E. A. Savateeva, L. P. Sidorova [et al.] // Experimental and Computational Biomedicine : Russian conference with international participation in memory of professor Vladimir S. Markhasin. - Ekaterinburg, 2016. - P65
ББК 61
Рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ
Кл.слова (ненормированные):
1,3,4-THIADIAZINE -- ANTIOXIDANTS -- DIABETES MELLITUS

\\\\Expert2\\NBO\\статьи из сборников\\Experimental and Computational Biomedicine 2016. - P. 65.pdf
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2.
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    2-Thiomorpholino-5-aryl-6 H-1,3,4-thiadiazine hydrobromides and their ability to inhibit nonenzymatic protein glycosylation / L. P. Sidorova, T. A. Tseitler, V. V. Emel’yanov [et al.] // Pharmaceutical Chemistry Journal. - 2017. - Vol. 51, № 1. - P9-12
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
GLYCOSYLATION -- ESTERIFICATION -- GLYCOSYL COMPOUNDS -- DEGLYCOSYLATION -- ?-HALOGENACETOPHENONES -- 1,3,4-THIADIAZINE -- 4-MORPHOLINE THIOSEMICARBAZIDES -- CYCLOCONDENSATION -- NONENZYMATIC PROTEIN GLYCOSYLATION
Аннотация: Cyclocondensation of α-halogenacetophenones with an original 4-morpholine thiosemicarbazide was used to synthesize a group of new Captions: of the 1,3,4-thiadiazine group, containing a thiomorpholine fragment at position 2 of the thiadiazine ring. Two members of this group of compounds were found to produce effective inhibition of nonenzymatic protein glycosylation in an in vitro model system. These test results allow compounds containing phenyl and fluorophenyl fragments IIIa and IIIb to be recommended for further study in in vivo experiments.

\\\\Expert2\\NBO\\Pharmaceutical Chemistry Journal\\2017 v.51 p.9-12.pdf
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3.
Инвентарный номер: нет.
   
   A 10


   
    A new approach to making autoprostheses for angioplasty / V. A. Chereshnev, B. G. Yushkov, N. V. Tyumentseva [et al.] // Doklady Biological Sciences. - 2006. - Vol. 408, № 1. - P211-213
ББК 57
Рубрики: БИОЛОГИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
ANGIOPLASTY -- ANIMAL -- AUTOTRANSPLANTATION

\\\\expert2\\nbo\\Doklady Biological Sciences\\2006. V. 408, N 1.P. 211-213.pdf
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4.
Инвентарный номер: нет.
   
   A 10


   
    A new experimental model of hemolitic anemia after butoxyethanol and the stady of its immunology / V. A. Chereshnev, P. V. Kosareva, L. V. Sivakova [et al.] // Perm medicine in the context of an international communicftion in science: book of abstracts of the scintific symposium in foreign languages with an international participation. - Perm, 2016. - P30
ББК 57
Рубрики: БИОЛОГИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
IMMUNOLOGICAL ACTIVITIES -- IMMUNOLOGY

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5.
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    A rat model of post-traumatic stress syndrome causes phenotype-associated morphological changes and hypofunction of the adrenal gland / V. Tseilikman, M. Komelkova, M. V. Kondashevskaya [et al.] // International journal of molecular sciences. - 2021. - Vol. 22. - Ст. 13235
Рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ
Кл.слова (ненормированные):
CPTSD -- GLUCOCORTICOIDS -- BEHAVIOR -- ADRENAL GLAND

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6.
Инвентарный номер: нет.
   
   A 10


   
    A systems immunology approach to plasmacytoid dendritic cell function in cytopathic virus infections. / G. Bocharov, R. Züst, L. Cervantes-Barragan [et al.] // PLOS pathogens. - 2010. - Vol. 6, № 7. - P1-15 : рис., a-табл. - Bibliogr. : p. 14-15 (52 ref.)
ББК 61
Рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ
Кл.слова (ненормированные):
ANTIVIRUS AGENT -- DENDRITIC CELL -- ALLERGY AND IMMUNOLOGY
Аннотация: Plasmacytoid dendritic cell (pDC)-mediated protection against cytopathic virus infection involves various molecular, cellular, tissue-scale, and organism-scale events. In order to better understand such multiscale interactions, we have implemented a systems immunology approach focusing on the analysis of the structure, dynamics and operating principles of virus-host interactions which constrain the initial spread of the pathogen. Using high-resolution experimental data sets coming from the well-described mouse hepatitis virus (MHV) model, we first calibrated basic modules including MHV infection of its primary target cells, i.e. pDCs and macrophages (Mphis). These basic building blocks were used to generate and validate an integrative mathematical model for in vivo infection dynamics. Parameter estimation for the system indicated that on a per capita basis, one infected pDC secretes sufficient type I IFN to protect 10(3) to 10(4) Mphis from cytopathic viral infection. This extremely high protective capacity of pDCs secures the spleen's capability to function as a 'sink' for the virus produced in peripheral organs such as the liver. Furthermore, our results suggest that the pDC population in spleen ensures a robust protection against virus variants which substantially down-modulate IFN secretion. However, the ability of pDCs to protect against severe disease caused by virus variants exhibiting an enhanced liver tropism and higher replication rates appears to be rather limited. Taken together, this systems immunology analysis suggests that antiviral therapy against cytopathic viruses should primarily limit viral replication within peripheral target organs

\\\\expert2\\nbo\\PLoS Pathogens\\2010. - Vol.6, № 7. - С. 1-15 .pdf
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7.
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    Alpha-fetoprotein as a factor of differentiation and functional activity of myeloid-derived suppressor cells / K. Yu. Shardina, S. A. Zamorina, V. P. Timganova [et al.] // Bulletin of experimental biology and medicine. - 2023. - Vol. 175. - P535–543
Рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ
Аннотация: We studied the role of alpha-fetoprotein (AFP) in regulation of differentiation and functional activity of human myeloid-derived suppressor cells (MDSC) in vitro. To obtain MDSC, CD11b+ cells were isolated from the peripheral blood of healthy donors followed by cytokine induction (IL-1β+GM-CSF) into the MDSC phenotype. The cell functions were assessed by the expression of indoleamine 2,3-dioxygenase (IDO) and arginase-1 (Arg1) and cytokine profile of the cell cultures. Native AFP did not affect the total number of MDSC and the percentage of polymorphonuclear MDSC (PMN-MDSC), but increased the number of monocytic MDSC (M-MDSC). AFP did not change the expression of Arg1, but in low concentrations (10 and 50 U/ml) increased the number of IDO-containing cells. AFP modulated the cytokine profile of CD11b+ cells: it reliably decreased the level of IL-19 (50 and100 U/ml) and showed a tendency to decrease the levels of IL-34, MMP-2, sCD163, CHI3L1, OPN and to increase the levels of IL-29, IL-32, APRIL, PTX3, and sTNF-R1. Thus, we have demonstrated a regulatory effect of native AFP at the level of MDSC generated from CD11b+ cells under conditions of cytokine induction in vitro.

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8.
Инвентарный номер: нет.
   
   A 53


   
    An extremal shift method for control of HIV infection dynamics / G. Bocharov, A. V. Kim, A. V. Krasovskii [et al.] // Russian Journal of Numerical Analysis and Mathematical Modelling . - 2015. - Vol. 30, № 1. - P11-25
ББК 61
Рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ
Кл.слова (ненормированные):
HIV INFECTION -- OPTIMAL OPEN-LOOP CONTROL -- EXTREMAL SHIFT METHOD
Аннотация: Optimal control problems for mathematical models describing HIV infection dynamics in a human body are considered in the paper. An overview of current approaches to solution of control problems for models of HIV dynamics is presented for techniques related to construction of optimal programme (open loop) or positional (feedback) controls for various criteria of control process quality and is based on the Pontryagin's maximum principle and the Bellman's theory of dynamic programming, respectively. In the framework of the theory of positional differential games of Krasovskii, there are constructive and efficient methods of synthesis of controls for different classes of dynamical systems. In this paper we present a formalization of a control problem for HIV infection considered as a corresponding positional differential game. The control algorithm based on the method of extremal shift is applied to the ODEs model of HIV infection. The numerical implementation of the extremal shift method is developed to construct the control taking the system to a neighbourhood of a given trajectory using the information on the dynamics of the guides or leaders.

\\\\expert2\\nbo\\Russian Journal of Numerical Anal. and Math. Modelling\\2015. V.30, N. 1. P. 11-30.pdf
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9.
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    Antinuclear autoantibodies in healthy individuals: autoimmunity is not a synonym of autoimmune disease : doi.org/10.3390/antib10010009 / I. A. Pashnina, I. M. Krivolapova, T. V. Fedotkina [et al.] // Antibodies. - 2021. - Vol. 10, № 1. - Ст. 9
Рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ
Аннотация: Incidence of autoimmune diseases increases. Antinuclear antibodies (ANA) testing is a critical tool for their diagnosis. However, ANA prevalence in health increased over last decades, especially among young people. ANA in health occur in low concentrations, with prevalence up to 50% in some populations, which demands a cutoff revision. The review deals with origin and probable physiological or compensatory function of ANA in health, according to the concept of immunological clearance, theory of autoimmune regulation of cell functions and the concept of functional autoantibodies. Considering ANA titers ≤1:320 as a serological marker of autoimmune diseases seems inappropriate. The role of anti-DFS70/LEDGFp75 autoantibodies is highlighted as possible anti-risk biomarker for autoimmune rheumatic disorders. ANA prevalence in health is different in various regions due to several underlying causes discussed in the review, all influencing in additive combinations according to the concept of the mosaic of autoimmunity. Not only titer, but the HEp-2 IFA staining patterns, like AC-2, is also important. Accepting autoantibodies as a kind of bioregulators, not only upper, but also lower borders of their normal range should be determined. Not only their excess, but also lack of them or “autoimmunodeficiency” could be a reason of disorders.

\\\\Expert2\\NBO\\Электрон. библиотека (Отеч.периодика)\\Черешнев В. А\\Antibodies. - 2021. - Vol. 10, № 1. - Ст. 9.pdf
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10.
Инвентарный номер: нет.
   


   
    Antinuclear autoantibodies in healthy individuals: autoimmunity is not a synonym of autoimmune disease / I. A. Pashnina, I. M. Krivolapova, T. V. Fedotkina [et al.] // Preprints. - 2020. - 28 Oct. - Ст. 2020100591. - 27 p.
Рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ
Аннотация: Incidence of autoimmune diseases increases. Antinuclear antibodies (ANA) testing is a critical tool for their diagnosis. However, ANA prevalence in health increased over last decades, especially among young people. ANA in health occur in low concentrations, with prevalence up to 50% in some populations, which demands a cutoff revision. The review deals with origin and probable physiological or compensatory function of ANA in health, according to the concept of immunological clearance, theory of autoimmune regulation of cell functions and the concept of functional autoantibodies. Considering ANA titers ≤1:320 as a serological marker of autoimmune diseases seems inappropriate. The role of anti-DFS70/LEDGFp75 autoantibodies is highlighted as possible anti-risk biomarker for autoimmune rheumatic disorders. ANA prevalence in health is different in various regions due to several underlying causes discussed in the review, all influencing in additive combinations according to the concept of the mosaic of autoimmunity. Not only titer, but the HEp-2 IFA staining patterns, like AC-2, is also important. Accepting autoantibodies as a kind of bioregulators, not only upper, but also lower borders of their normal range should be determined. Not only their excess, but also lack of them or “autoimmunodeficiency” could be a reason of disorders.

\\\\Expert2\\NBO\\Электрон. библиотека (Отеч.периодика)\\Черешнев В. А\\Preprints 2020 Ст. 2020100591.pdf
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11.
Инвентарный номер: нет.
   


    Chuchalin, A. G.
    Bioethics, artificial intelligence and medical diagnostics / A. G. Chuchalin, V. A. Chereshnev, V. Ju. Mishlanov, Ya. V. Mishlanov [et al.]. - Perm : [s. n.], 2019. - 184 p. - ISBN 978-5-91252-147-8 : Б. ц.
Рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ
Кл.слова (ненормированные):
БИОЭТИКА -- ИСКУССТВЕННЫЙ ИНТЕЛЛЕКТ -- ДИАГНОСТИКА МЕДИЦИНСКАЯ

\\\\Expert2\\NBO\\Электрон. библиотека (Отеч.периодика)\\Черешнев В. А\\Bioethics, artificial intelligence and medical diagnostics. - Perm, 2019.pdf
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12.
Инвентарный номер: нет.
   
   C 36


   
    CD4+ T-cell cycling in hiv-infected patients with the discordant immunologic response to the antiretroviral therapy [Text] / E. V. Saidakova, K. V. Shmagel, L. B. Korolevskaya [et al.] // Cell and Tissue Biology. - 2019. - Vol. 13, № 1. - P55-63
ББК Р
Рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ

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13.
Инвентарный номер: нет.
   
   C 36


   
    CD8.sup.+ T cell expansion in HIV/HCV coinfection is associated with systemic inflammation / E. V. Saidakova, K. V. Shmagel, L. B. Korolevskaya [et al.] // Doklady Biological Sciences. - 2017. - Vol. 474, № 1. - P126-128
ББК 001.2
Рубрики: НАУКА. НАУКОВЕДЕНИЕ
Кл.слова (ненормированные):
HEPATITIS C -- RISK FACTORS -- COMORBIDITY -- RISK FACTORS -- T CELLS -- HEPATITIS C VIRUS
Аннотация: High prevalence of non-AIDS-defining illnesses in treated HIV-infected patients is associated with increased peripheral CD8.sup.+ T cell counts. Hepatitis C virus (HCV) coinfection is an additional risk factor for the development of non-AIDS events. We found that, in HIV/HCV coinfection, the increased proportion of CD8.sup.+ T lymphocytes is due to the effector memory and terminal effector T cells gain. Moreover, in these patients, the accumulation of highly differentiated forms of CD8.sup.+ T lymphocytes was associated with increased concentrations of inflammatory indices.

\\\\Expert2\\NBO\\Doklady Biological Sciences\\2017 v. 474 p. 126-128.pdf
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14.
Инвентарный номер: нет.
   54
   C 45


   
    Changes of immune system functions and its correction under penetrating eye injury / Ju. I. Shilov, M. V. Chereshneva, T. V. Gavrilova [et al.] // New Frontiers in Ophthalmology. - 2017. - V 3, № 4. - P1-7
ББК 54
Рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ

\\\\Expert2\\NBO\\New Frontiers in Ophthalmology\\2017 V 3 N 4 p. 1-7.pdf
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15.
Инвентарный номер: нет.
   


   
    Checking gene expression profile associated with IRF7 and UNC93B deficient patient peripheral blood mononuclear cells infected with pH1N1 influenza virus / K. Shinwari, G. Liu, M. A. Bolkov [et al.] // AIP Conference Proceedings. - 2022. - Vol. 2390, № 1. - Ст. 030089
Рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ
Кл.слова (ненормированные):
VIRUSES -- MICROARRAYS -- GENOMICS
Аннотация: An innate immune defect is a defect in the innate immune response that reduces the response to infection, this can occurs in genes important for activation regulation and proliferation of the innate immune cells or pathways important for the function of innate immunity. The purpose of this study was to identify novel biomarkers of interferon Receptor 7 through bioinformatics analysis and elucidate the possible molecular mechanism. The GSE 66486 datasets containing microarray data from IRF7 and UNC93B patients and healthy controls were downloaded from the GEO database and analyzed by the GEO2R web tool to obtain different expressed genes (DEGs). Gene Ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis, protein-protein interaction (PPI), and Biological Networks Gene Oncology tool (BiNGO) were then performed to elucidate the molecular mechanism of IRF7. A total of 490 DEGs were identified, of which 14 were hub genes, and involved in ribosome biogenesis, rRNA processing, gene expression, mRNA processing, nuclear lumen, intracellular non-membrane-bounded organelle, nucleoplasm, small-subunit processome, antigen processing and presentation pathway, and ribosome biogenesis in eukaryotes. Antigen processing and presentation pathway, and ribosome biogenesis in eukaryotes possibly form the basis of IRF7 or UNC93B disorders, while our study provides a list of genes and pathways that are disrupted in IRF7/UNC93B, which has the potential to be used in the clinic for diagnosis and targeted therapy of such disorders in future.

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16.
Инвентарный номер: нет.
   


   
    Checking gene expression profile associated with IRF7 and UNC93B deficient patient peripheral blood mononuclear cells infected with pH1N1 influenza virus / K. Shinwari, G. Liu, M. Bolkov [et al.] // AIP Conference Proceedings. - 2022. - Vol. 2390, № 1. - P 030089
Рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ

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17.
Инвентарный номер: нет.
   
   C 73


   
    Complete genome sequences of emm111 type streptococcus pyogenes strain GUR, with antitumor activity, and Its derivative strain GURSA1 with an Inactivated emm gene / M. Suvorova, A. Tsapieva, E. Bak [et al.] // Genome Announcements. - 2017. - Vol. 5, № 38. - Pe00939-17[1-2]
ББК 61
Рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ
Аннотация: We present here the complete genome sequence of Streptococcus pyogenes type emm111 strain GUR, a throat isolate from a scarlet fever patient, which has been used to treat cancer patients in the former Soviet Union. We also present the complete genome sequence of its derivative strain GURSA1 with an inactivated emm gene.

\\\\Expert2\\NBO\\Genome Announcements\\2017 V 5 N 38 P. e00939-17.pdf
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18.
Инвентарный номер: нет.
   


   
    Defining muscle-invasive bladder cancer immunotypes by introducing tumor mutation burden, CD8+ T cells, and molecular subtypes / Zihao Chen, Guojun Liu, Guoqing Liu [et al.]. - https://doi.org/10.1186/s41065-020-00165-7 // Hereditas. - 2021. - Vol. 158, № 1. - 12 p
Кл.слова (ненормированные):
CD8+ T CELLS -- MOLECULAR SUBTYPE -- IMMUNOTHERAPY
Аннотация: Immunotherapy, especially anti-PD-1, is becoming a pillar of modern muscle-invasive bladder cancer (MIBC) treatment. However, the objective response rates (ORR) are relatively low due to the lack of precise biomarkers to select patients. Herein, the molecular subtype, tumor mutation burden (TMB), and CD8+ T cells were calculated by the gene expression and mutation profiles of MIBC patients. MIBC immunotypes were constructed using clustering analysis based on tumor mutation burden, CD8+ T cells, and molecular subtypes. Mutated genes, enriched functional KEGG pathways and GO terms, and co-expressed network-specific hub genes have been identified. We demonstrated that ORR of immunotype A patients identified by molecular subtype, CD8+ T cells, and TMB is about 36% predictable. PIK3CA, RB1, FGFR3, KMT2C, MACF1, RYR2, and EP300 are differentially mutated among three immunotypes. Pathways such as ECM-receptor interaction, PI3K-Akt signaling pathway, and TGF-beta signaling pathway are top-ranked in enrichment analysis. Low expression of ACTA2 was associated with the MIBC survival benefit. The current study constructs a model that could identify suitable MIBC patients for immunotherapy, and it is an important step forward to the personalized treatment of bladder cancers.

\\\\Expert2\\NBO\\Электрон. библиотека (Отеч.периодика)\\Черешнев В. А\\Hereditas. - 2021. - Vol. 158, № 1.pdf
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19.
Инвентарный номер: нет.
   
   D 64


   
    Diverse expression of toll-like receptor-9 and β-defensin-2 in corneal cells during herpes simplex vIrus-1 keratitis / L. V. Gankovskaya, O. A. Svitich, V. A. Chereshnev [et al.] // International trends in immunity. - 2014. - Vol. 2, № 3. - P128-133. - Bibliogr. : p. 132-133 (31 ref.)
ББК 61
Рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ
Кл.слова (ненормированные):
HERPES SIMPLEX -- CORNEAL CELLS -- VIRUS-1 KERATITIS

\\\\expert2\\nbo\\Internationals Trends in Immunity\\2014. V. 2, N 3. P. 128-133.pdf
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20.
Инвентарный номер: нет.
   
   D 69


   
    Does alpha-fetoprotein adjust Treg / Th17-balance in pregnancy? / S. A. Zamorina, V. P. Timganova, M. S. Bochkova [et al.] // Immunome Research. - 2018. - Vol. 14: 11th Annual Congress on Immunology & Immunotechnology: conference proceedings. - P62
ББК 53
Рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ

\\\\Expert2\\NBO\\Электрон. библиотека (Отеч.периодика)\\Черешнев В. А\\Immunome Research 2018 Vol. 14 P. 62.pdf
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