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1.
Инвентарный номер: нет.
   
   S 96

    Sviridova, T. G.
    Homoserine lactones and resorcinolic lipids inhibit In vitro pro-and anti-inflammatory cytokine production / T. G. Sviridova, D. G. Deryabin, V. A. Chereshnev // Research Journal of Immunology. - 2013. - Vol. 6, № 1. - P7-16. - Библиогр.: с. 14-16 (27 ref.)
ББК 61
Рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ
Кл.слова (ненормированные):
HOMOSERINE LACTONES -- RESORCINOLIC LIPIDS -- IMMUNE SYSTEM
Аннотация: Homoserine Lactones (HSLs) and Resorcinolic Lipids (RLs) originating from microbes and plants influence immune system, however, it is currently unclear whether HSLs and RLs are activators or suppressors of the cytokine network, especially in humans. A study has been carried out to investigate the effects of pure, synthetic HSLs and RLs with different chain lengths on pro-and anti-inflammatory cytokines produced by human blood monocyte cultures. Human monocytes (macrophages and lymphocytes) were collected from leukocyte-rich plasma, separated on a double density gradient, pre-treated with HSLs or Rls and then were inducted with standard either lipopolysaccharide or phytohemagglutinin stimulus. Quantitative assays for pro-and anti-inflammatory cytokines in the monocyte culture supernatants were performed using enzyme immunoassay kits for the quantitative determination of IL-1β, IL-2, IL-4, IL-10, TNF-α and IF-γ. We observed differences in cytokine production according to HSL and RL pre-treatment, increasing in the following order: IL-1β→IL-2≈IL-10≈TNF-α→IL-4→IF-γ. HSLs have been shown more pronounced inhibitory effects than Rls and long-chained homologs were more active than short-chained ones. Our study suggests that some small molecules originating from microbes and plants play an important role in cytokine network regulation and the immunomodulatory effect of HSLs and RLs may obstruct host defenses and affect inflammatory processes

\\\\expert2\\NBO\\Research Journal of Immunology\\2013. V. 6, N 1. P. 7-16.pdf
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2.
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   M 81

   
    Monitoring the state of the immune system of persons working in the potassium salt industry [Text] / S. V. Shirshev, V. A. Chereshnev, S. A. Zamorina, V. A. Lopatina // Russian Journal of Ecology. - 2003. - Vol. 34, № 2. - P127-132
ББК 57
Рубрики: БИОЛОГИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
HALITE WASTE -- IMMUNE SYSTEM -- POTASSIUM SALT INDUSTRY
Аннотация: The immune status of basically healthy personnel of OAO Uralkalii and OAO Sil'vinit was studied for three years (1998-2000) to assess the effect of the workplace environment on the parameters of the immune system. All probands were divided into groups depending on their exposure to salts or halite waste. Annual examination did not reveal any statistically significant differences between the parameters of immunograms in the groups studied. The parameters of the humoral component of the immune system of potassium-industry workers manifested a stable tendency toward normalization, irrespective of whether or not these persons were exposed to salts, and the annual contents of T and B lymphocytes and phagocytizing cells were stable within the regional standards

\\\\expert2\\nbo\\Russian Journal of Ecology\\2003. V. 34, N 2. P. 127-132.pdf
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3.
Инвентарный номер: нет.
   
   T 44

   
    The blood system and the organism adaptation to extreme factor / V. A. Chereshnev, B. G. Lushkov, M. N. Sumin, N. V. Tyumentseva, I. S. Khramtsova, I. G. Danilova // Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova / Rossiiskaia akademiia nauk . - 2004. - Vol.90, №10. - P1193-1202
ББК 61
Рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ
Кл.слова (ненормированные):
HEMOGLOBIN -- HEMATOPOIESIS -- LEUKOCYTE
Аннотация: The formation of blood system adoptive reaction in many cases is defined by the type of action and the condition of hemopoietic inductive microenvironment: hemodynamics of hemopoietic tissue, functional conditions of bone marrow macrophages, mast cells and glycosaminoglycans content. The shift in hemodlobin fraction occurs in extreme conditions requiring an increased gas transport by the blood. In case of tissue lesion, lymphocytes stimulate their regeneration. Morphogenetic function of lymphoid cells may be alerted by immunomodulators. Blood cells participate in angiogenesis, and this property may be used for vessel grafts production

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4.
Инвентарный номер: нет.
   
   G 33

    Gein, S. V.
    Effect of beta-endorphin and DAGO, a selective agonist of mu-opioid receptors, on the proliferative activity of lymphocytes / S. V. Gein, T. A. Simonenko, V. A. Chereshnev // Doklady Biological Sciences. - 2003. - Т. 391, № 1-6. - С. 289-291. - Bibliogr. : p. 291 (14 ref.)
ББК 61
Рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ
Кл.слова (ненормированные):
DAGO -- LYMPHOCYTES -- BETA-Endorphin

\\\\expert2\\nbo\\Doklady Biological Sciences\\2003. V. 391, P. 289-291.pdf
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5.
Инвентарный номер: нет.
   

   
    Th17-lymphocytes and their cytokines in pathogenesis of autoimmune thyroiditis, aсcompanied by psychiatric disorders / P. A. Sobolevskaya, A. N. Gvozdeckii, I. V. Kudryavtsev [et al.] // 9th International Congress of Pathophysiology and 5th Congress of Physiological Sciences of Serbia with International Participation. Final Program and Abstract Book. - Kragujevac, 2023. - P50
Рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ
Кл.слова (ненормированные):
AUTOIMMUNE THYROIDITIS -- PSYCHIATRIC DISORDERS -- LYMPHOCYTES

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6.
Инвентарный номер: нет.
   
   T 44

   
    Role of alpha-fetoprotein in differentiation of regulatory t-lymphocytes / V. A. Chereshnev, V. P. Timganova, S. A. Zamorina [et al.] // Doklady Biological Sciences. - 2017. - Vol. 477. - P248-251
ББК 24
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Аннотация: The effect of native а-fetoprotein (AFP) on the expression of T-regulatory lymphocyte (Treg) markers by activated CD4+ lymphocytes with different proliferative status was studied. а-Fetoprotein did not affect the ratio of proliferating and non-proliferating activated CD4+ cells. In the study of Treg differentiation, it was found that AFP at concentrations of 50 and 100 mg/mL significantly inhibited the number of non-proliferating CD4+FOXP3+ and CD4+FOXP3+HELIOS+ lymphocytes without affecting the expression of Treg markers by proliferating CD4+ lymphocytes.

\\\\Expert2\\NBO\\Doklady Biological Sciences\\2017. - Vol. 477 - P. 248-251.pdf
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7.
Инвентарный номер: нет.
   
   C 36

   
    CD8.sup.+ T cell expansion in HIV/HCV coinfection is associated with systemic inflammation / E. V. Saidakova, K. V. Shmagel, L. B. Korolevskaya [et al.] // Doklady Biological Sciences. - 2017. - Vol. 474, № 1. - P126-128
ББК 001.2
Рубрики: НАУКА. НАУКОВЕДЕНИЕ
Кл.слова (ненормированные):
HEPATITIS C -- RISK FACTORS -- COMORBIDITY -- RISK FACTORS -- T CELLS -- HEPATITIS C VIRUS
Аннотация: High prevalence of non-AIDS-defining illnesses in treated HIV-infected patients is associated with increased peripheral CD8.sup.+ T cell counts. Hepatitis C virus (HCV) coinfection is an additional risk factor for the development of non-AIDS events. We found that, in HIV/HCV coinfection, the increased proportion of CD8.sup.+ T lymphocytes is due to the effector memory and terminal effector T cells gain. Moreover, in these patients, the accumulation of highly differentiated forms of CD8.sup.+ T lymphocytes was associated with increased concentrations of inflammatory indices.

\\\\Expert2\\NBO\\Doklady Biological Sciences\\2017 v. 474 p. 126-128.pdf
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8.
Инвентарный номер: нет.
   
   I-60

   
    Influence of myelopid, myelopeptides MP-5 and MP-6 on lymphocyte proliferative activity / T. V. Gavrilova, S. V. Gein, T. A. Pogudina, V. A. Chereshnev // Doklady Akademii Nauk . - 2004. - Vol.398, №4. - P560-562
ББК 57
Рубрики: БИОЛОГИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
CELL CULTURE -- COMPOSITION EFFECTS -- LYMPHOCYTES
Аннотация: The effect on activity of peripheral blood lymphocytes upon blast-transformation reaction induced by phytohemagglutinin (PGA) in different concentrations was investigated. For the first time the different-directed activity of MP-6 tetrapeptide in respect to stimulated PGA and non-stimulated peripheral blood lymphocytes is shown. Dependence of MP-6 effects on its own concentration as well as on the mitogen concentration in the cell culture is demonstrated. Myelopid and MP-5 didn't affect the lymphocyte functional activity

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9.
Инвентарный номер: нет.
   
   I-57

   
    In vitro cytokine stimulation assay for glycolipid biosurfactant from Rhodococcus ruber: Role of monocyte adhesion / S. V. Gein, M. S. Kuyukina, I. B. Ivshina, V. A. Chereshnev // Cytotechnology. - 2011. - Vol. 63, № 6. - P559-566. - Bibliogr. : p. 565-566 (23 ref.)
ББК 61
Рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ
Кл.слова (ненормированные):
CYTOKINE-STIMULATING ACTIVITY -- GLYCOLIPID BIOSURFACTANT -- MONOCYTE ADHESION
Аннотация: Glycolipid biosurfactant (GLB) from Rhodococcus ruber IEGM 231 was found to stimulate tumor necrosis factor-α (TNF-α), interleukin (IL) -1β and IL-6 production when applied as an ultrasonic emulsion to the adherent human peripheral blood monocyte culture. However, a lack of cytokine-stimulating activity was registered with the GLB applied as a hydrophobic film coating in 24-well culture plates, indicating that it may have been due to its inhibitory effect on monocyte adhesion. The mode of GLB application may therefore play an important role in in vitro assay of immunostimulatory activity of this compound as well as other bacterial glycolipids. Additionally, GLB from R. ruber displayed no cytotoxicity against human lymphocytes and therefore could be proposed as a potential immunomodulating and antitumor ag

\\\\expert2\\NBO\\Cytotechnology\\2011. V. 63, N 6. P. 559-566.pdf
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10.
Инвентарный номер: нет.
   
   R 30

   
    Reaction diffusion modelling of interferon distribution in secondary lymphoid organs / G. Bocharov, A. Danilov, Y. Vassilevski [et al.] // Mathematical modelling of natural phenomena. - 2011. - Vol. 6, № 7. - P13-26
ББК Ч2
Рубрики: НАУКА. НАУКОВЕДЕНИЕ
Кл.слова (ненормированные):
SYSTEMS -- RECIRCULATION -- LYMPHOCYTES
Аннотация: This paper proposes a quantitative model of the reaction-diffusion type to examine the distribution of interferon-alpha (IFN alpha) in a lymph node (LN). The numerical treatment of the model is based on using an original unstructured mesh generation software Ani3D and nonlinear finite volume method for diffusion equations. The study results in suggestion that due to the variations in hydraulic conductivity of various zones of the secondary lymphoid organs the spatial stationary distribution of IFN alpha is essentially heterogeneous across the organs. Highly protected domains such as sinuses, conduits, co-exist with the regions in which where the stationary concentration of IFN alpha is lower by about 100-fold. This is the first study where the spatial distribution of soluble immune factors in secondary lymphoid organs is modelled for a realistic three-dimensional geometry

\\\\expert2\\nbo\\Mathematical Modelling and Natural Phenomena\\2011. Vol.6, №7. С. 13-26.pdf
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