E 27 Effects of myelopeptides on immune response and morphometrical manifestations of inflammation in experimental penetrating wound of the eye / N. L. Berkasova, T. V. Gavrilova, Yu. I. Shilov [et al.] // Bulletin of experimental biology and medicine. - 2008. - Vol. 145, № 3. - P341-343 Рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ Кл.слова (ненормированные): MYELOPEPTIDES -- MYELOPID -- PENETRATING WOUND OF THE EYE Аннотация: Myelopid and MP-1 myelopeptide increase the count of antibody-producing cells, reduced under the effect of injury and standard therapy, and do not modify the suppression of delayed hypersensitivity. Injections of myelopid and MP-3 together with standard drugs optimized the traumatic inflammation processes \\\\expert2\\nbo\\Bulletin of Experimental Biology and Medicine\\2008, v.145, N 3, p. 341.pdf |
M 99 Myelopeptides regulate the microbicidic and secretory activities of Innate immunity effectors / V. A. Chereshnev, S. V. Gein, L. S. Mazunina [et al.] // Doklady biochemistry and biophysics. - 2011. - Vol. 436, № 1. - P53-55. - Bibliogr. : p. 55 (9 ref.) Рубрики: БИОЛОГИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): MYELOPEPTIDES -- MICROBICIDIC -- INNATE iMMUNITY \\\\expert2\\NBO\\Doklady Biological Sciences\\2011. V. 436, N 1.P. 53-55.pdf |
E 27 Effect of myelopeptides on reactive oxygen species generation and IL-1beta and TNF-alpha production by peripheral blood cells / // Patologicheskaia fiziologiia i èksperimental'naia terapiia. - 2012. - № 1. - P19-22 Рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ Кл.слова (ненормированные): IL1B PROTEIN -- HUMAN -- IMMUNOLOGICAL ADJUVANT Аннотация: Myelopeptides MP-3, MP-5, and MP-6 were found to suppress zymosan-induced production of reactive oxygen species by leukocytes both under one-way introduction and under pretreatment. All of myelopeptides under examination in case of one-way introduction in cultures with zymosan demonstrated a decrease in zymosan-stimulated (1500 mkg/ml) production of IL-1beta, and activation of spontaneous production of this cytokine by whole blood cells. TNF-alpha production under myelopeptide effect was lowered in cultures with 150 mkg/ml zymosan. Under pretreatment myelopeptides did not render effect on IL-1beta and TNF-alpha production, with the exception of single stimulating effect of MP-5 on IL-1beta level in spontaneous cultures. Using comparative analysis the difference in direction and expressivity of effects of various myelopeptides was not revealed that suggests the existence of common mechanism of action in this group of peptide bioregulators. |
G 33 Gein, S. V. Effect of myelopeptides on IFN-γ and IL-4 production by peripheral blood lymphocytes [Electronic resource] / S. V. Gein, T. V. Gavrilova, V. A. Chereshnev // Doklady Biological Sciences. - 2007. - Vol. 413, № 1. - P161-163 : рис., a-табл. Рубрики: БИОЛОГИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): MYELOPEPTIDES -- IL-4 PRODUCTION -- LYMPHOCYTES \\\\expert2\\NBO\\Doklady Biological Sciences\\2007. V. 413, N 1.P. 161.pdf |
M 99 Myelopeptides in treatment for stress- and injury-induced changes in the immune response to a heterologous thymus-dependent antigen in rats with penetrating eye wounds [Electronic resource] / T. V. Gavrilova, N. L. Berkasova, Yu. I. Shilov, M. V. Chereshneva, V. A. Chereshnev // Doklady Biological Sciences. - 2007. - Vol. 412, № 1. - P8-10 Рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ Кл.слова (ненормированные): ANTIGEN -- MYELOPEPTIDES -- OLIGOPEPTIDE \\\\expert2\\nbo\\Doklady Biological Sciences\\2007. V. 412, N 1.P. 8-10.pdf |
E 71 Erratum: ''Myelopeptides in treatment for stress-and injury-induced changes in the immune response to a heterologous thymus-dependent antigen in rats with penetrating eye wounds'' [Doklady Biological Sciences (2007) 412 (8-10)] / T. V. Gavrilova, N. L. Berkasova, Yu. I. Shilov , V. A. Chereshnev, M. V. Chereshneva // Doklady Biological Sciences. - 2007. - Vol. 414, № 1. - P251 Рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ Кл.слова (ненормированные): MYELOPEPTIDES -- IMMUNE RESPONSE -- ANTIGEN |
M 45 Mechanism underlying the effect of myelopeptides on lymphocyte proliferation in vitro [Electronic resource] / T. V. Gavrilova, S. V. Gein, T. A. Pogudina, V. A. Chereshnev // Bulletin of experimental biology and medicine. - 2005. - Vol. 140, № 1. - P74-76. - Bibliogr. : p. 76 (7 ref.) Рубрики: БИОЛОГИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): LYMPHOCYTE BLAST TRANSFORMATION -- MONOCYTES -- MYELOPEPTIDES Аннотация: We studied the role of monocytes in the effect of myelopid and myelopeptides MP-1, MP-3, MP-5, and MP-6 on functional activity of peripheral blood lymphocytes in the reaction of blast transformation. Myelopeptides MP-1, MP-3, and MP-6 suppressed blast transformation of lymphocytes. The effect depended on the presence of monocytes in a cell culture \\\\expert2\\NBO\\Bulletin of Experimental Biology and Medicine\\2005, v.140, N 1, p. 74.pdf |
I-60 Influence of myelopid, myelopeptides MP-5 and MP-6 on lymphocyte proliferative activity / T. V. Gavrilova, S. V. Gein, T. A. Pogudina, V. A. Chereshnev // Doklady Akademii Nauk . - 2004. - Vol.398, №4. - P560-562 Рубрики: БИОЛОГИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): CELL CULTURE -- COMPOSITION EFFECTS -- LYMPHOCYTES Аннотация: The effect on activity of peripheral blood lymphocytes upon blast-transformation reaction induced by phytohemagglutinin (PGA) in different concentrations was investigated. For the first time the different-directed activity of MP-6 tetrapeptide in respect to stimulated PGA and non-stimulated peripheral blood lymphocytes is shown. Dependence of MP-6 effects on its own concentration as well as on the mitogen concentration in the cell culture is demonstrated. Myelopid and MP-5 didn't affect the lymphocyte functional activity |
E 27 Effects of myelopidum and myelopeptides MP-5 and MP-6 on lymphocyte proliferative response / T. V. Gavrilova, S. V. Gein, T. A. Pogudina, V. A. Chereshnev // Doklady Biological Sciences. - 2004. - Vol. 398. - P360-362 Рубрики: БИОЛОГИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): MYELOPEPTIDES -- MYELOPIDUM -- OLIGOPEPTIDE \\\\expert2\\NBO\\Doklady Biological Sciences\\2004. V. 398, P. 360-362.pdf |
I-55 Immune Alterations and Immunocorrection by Myelopidum under Penetrating Eye Injury / M. V. Chereshneva, Yu. I. Shilov , V. Usova, T. V. Gavrilova, V. A. Chereshnev // International Immunology. - 2010. - Vol. 22, № 1 : XIVth International Congress of Immunoiogy, Kobe, Japan, August 22-27 2010. - Piv179 Рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ Кл.слова (ненормированные): PENETRATING EYE INJURY -- MYELOPEPTIDES |
E 27 Effect of myelopeptides on functions of phagocytic cells under the experimental eye penetrating wound / T. V. Gavrilova, S. V. Gein , Ju. I. Shilov, A. A. Mikhailova, V. A. Chereshnev // Scandinavian Journal of Immunology. - 2001. - Vol. 54. Suppl. 1 (July/August 2001). - P115 Рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ Кл.слова (ненормированные): MYELOPEPTIDES -- PHAGOCYTIC CELLS |
I-60 Influence of myelopeptides on functiones of phagocytic cells under the experimental penetrating eye injury / T. V. Gavrilova, S. V. Gein , A. A. Mikhailova, N. N. Kevorkov, M. V. Chereshneva, V. A. Chereshnev // Environmental Pollution. ICEP-2001: V International Conference : abstracts, Volgograd - Perm, 12-25 September 2001. - Volgograd ; Perm, 2001. - P68 Рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ--МЕДИЦИНСКАЯ ИММУНОЛОГИЯ--ИММУНОПАТОЛОГИЯ--СБОРНИКИ Кл.слова (ненормированные): ИММУНОЛОГИЯ (ИССЛЕДОВАНИЯ) -- ИММУНОЛОГИЧЕСКИЕ ФАКТОРЫ -- ИММУНОЛОГИЧЕСКИЙ МОНИТОРИНГ |
В 58 Влияние МП-3 на продукцию активных форм кислорода, IL-1β И TNF-α перитонеальными макрофагами мышей при проникающем ранении глаза / Т. В. Гаврилова, Л. С. Журавлева, М. В. Черешнева [и др.] // Российский иммунологический журнал. - 2017. - Т. 11, № 2. - С. 271-273 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): ПРОНИКАЮЩЕЕ РАНЕНИЕ ГЛАЗА -- МАКРОФАГИ -- МИЕЛОПЕПТИДЫ -- АКТИВНЫЕ ФОРМЫ КИСЛОРОДА -- ЦИТОКИНЫ -- PENETRATING EYE INJURY -- MACROPHAGES -- MYELOPEPTIDES -- REACTIVE OXYGEN SPECIES -- CYTOKINES Аннотация: Таким образом, миелопептид МП-3 оказывает модулирующее действие на функции перитонеальных макрофагов, отменяя индуцированное проникающим ранением глаза усиление продукции IL-1β. \\\\Expert2\\NBO\\Электрон. библиотека (Отеч.периодика)\\Российский иммунологический журнал\\2017 Т.11 № 2 С.271-273 .pdf |
R 35 Regulation of the peritoneal macrophage functional activity by the MP-5 and MP-6 myelopeptides under stress / S. V. Gein, T. V. Gavrilova, O. N. Gein [et al.] // Doklady Biological Sciences. - 2017. - Vol. 475, № 1. - P154-156 Рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ Кл.слова (ненормированные): PEPTIDES -- MACROPHAGES -- ACTIVE OXYGEN Аннотация: In mice, two-hour immobilization stress inhibited zymosan-induced production by macrophages of the oxygen radicals and cytokine IL-1[beta]. After myelopeptides MP-5 and MP-6 were administered into mice, the stress-induced inhibition of the reactive oxygen species (ROS) and IL-1[beta] was abrogated. MP-5 peptide stimulated spontaneous ROS production by macrophages and reduced IL-10 production under stress. Thus, under in vivo conditions and under stress, the effect of MP-5 and MP-6 myelopeptides modulates the peritoneal macrophage activity. \\\\Expert2\\NBO\\Doklady Biological Sciences\\2017. - Vol. 475, № 1. - P. 154.pdf |