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1.
Инвентарный номер: нет.
   


   
    (A)symmetric chromophores based on cyano and fluorine-substituted 2,3-bis(5-arylthiophen-2-yl)quinoxalines: Synthesis, photophysical properties and application prospects / T. N. Moshkina, E. V. Nosova, A. E. Kopotilova [et al.] // Dyes and Pigments. - 2022. - Vol. 204. - Ст. 110434
Рубрики: ХИМИЧЕСКИЕ НАУКИ

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2.
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    1,3-Dipolar cycloaddition of 3-alkylsulfanyl-2-arylazo-3-(tert-cycloalkylamino)acrylonitriles with N-methyl- and N-phenylmaleimides / N. P. Belskaia, S. G. Lesogorova, J. O. Subbotina, A. V. Koksharov, P. A. Slepukhin, W. Dehaen, V. A. Bakulev // Tetrahedron. - 2015. - Vol. 71. - С. 1438-1447
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
1,3-DIPOLAR CYCLOADDITION -- 3-ALKYLSULFANYL -- N-PHENYLMALEIMIDES

\\\\expert2\\NBO\\Tetrahedron\\2015, v. 71 , p. 1438.pdf
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3.
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    1,3-Dipolar cycloadditions of nonstabilised azomethine ylides at 3-substituted coumarins: synthesis of 1-benzopyrano[3,4-c]pyrrolidines / V. S. Moshkin, V. Ya. Sosnovskikh, P. A. Slepukhin, Gerd-Volker Röschenthalerc // Mendeleev Communications. - 2012. - Vol.22, №1. - С. 29-31
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
COUMARINS -- AZOMETHINE YLIDES -- PYRROLIDINES
Аннотация: Reaction of 3-substituted coumarins with N-alkyl-α-amino acids and aldehydes proceeds regio- and stereoselectively to give 1-benzopyrano[3,4-c]pyrrolidines as a result of 1,3-dipolar cycloaddition of the intermediate azomethine ylides at the Δ3-bond of the coumarins

\\\\Expert2\\nbo\\Mendeleev Communications\\2012, v.22, p. 29.pdf
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4.
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    1H-pyrazole-appended pyridines and their 1,2,4-triazine precursors: a rational synthesis and in silico and in vitro evaluation of anti-cancer activity / A. P. Krinochkin, Y. K. Shtaitz, A. K. Rammohan [et al.] // European Journal of Organic Chemistry. - 2022. - Vol. 2022, № 22. - Pe202200227
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Аннотация: An operationally facile and high yielding one-pot protocol has been developed for the preparation of pyridines appended with pyrazole via NH linker. This protocol includes SNipso/aza-Diels-Alder reactions in up to 54 % yields starting from 1,2,4-triazine precursors. All the synthesized compounds have been evaluated for their in silico activity against JAK1, SYK, and FAK1 kinases. The most promising compound was tested in vitro using A-172, Hs578T, and HepG2 cancer cell lines and exhibited considerable cytotoxicity with IC50 values 50 μM in A-172 and HepG2 cell lines. Anticancer in vitro activity correlates well with the predicted in silico data.

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5.
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    2,2 '-Bipyridinyl carboranes as B,N,N-ligands in cyclometallated complexes of platinum(II) [] / A. M. Prokhorov, P. A. Slepukhin, V. L. Rusinov, V. N. Kalinin, D. N. Kozhevnikov // Chemical Communications. - 2011. - Vol. 47, № 27. - С. 7713-7715
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
O-CARBORANE -- METALLACARBORANES -- PHOTOLUMINESCENT
Аннотация: Novel B,N,N-cyclometallated Pt(II) complexes of 2,2'-bipyridin-6-yl carboranes exhibit absorption and emission similar to relative Pt(II) complexes of aromatic C,N,N-ligands: the same transitions but lower intensities. DFT calculations suggest the former emits from the (3)MLCT state while for the latter the mixed (3)ICT-MLCT transitions should be considered

\\\\expert2\\NBO\\Chemical Communications\\2011,v.47. p.7713.pdf
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6.
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    2,3-Dichloro-1-alkylpyrazinium tetrafluoroborates: the synthesis and reactions with nucleophiles [Electronic resource] / G. L. Rusinov, P. A. Slepukhin, V. N. Charushin, O. N. Chupakhin // Mendeleev Communications. - 2001. - Vol. 11, № 2. - P78-80
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Аннотация: The alkylation of 2,3-dichloropyrazine with the Meerwein reagents afforded 1-alkyl-2,3-dichloropyrazinium tetrafluoroborates, which were transformed into mono.mono- or disubstitution products, while the reaction of these salts with 1,4-N,Xdinucleophiles resulted in fused heterocyclic systems

\\\\expert2\\nbo\\Mendeleev Communications\\2001, v.11, N 2. p.78.pdf
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7.
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    2,3-Epoxyperfluoro-2-methylpentane in reactions with urea and thiourea [Electronic resource] / T. I. Filyakova, V. I. Saloutin, A. Ya. Zapevalov, P. A. Slepukhin, M. I. Kodess, V. I. Saloutin // Russian Journal of Organic Chemistry (Translation of Zhurnal Organicheskoi Khimii). - 2011. - Vol. 47, № 5. - P650-658 : рис., табл. - Bibliogr. : p. 658 (24 ref.)
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Аннотация: 2,3-Epoxyperfluoro-2-methylpentane reacts with thiourea in protic (methanol, 2-propanol) and aprotic (dioxane) solvents, and also with urea in acetonitrile affording unexpected products: 1-(2,2,3,3,3-pentafluoropropionyl)-2-(2,2,2-trifluoro-1-trifluoro-methylethyl)isothiourea, and 1-(2,2,3,3,3-pentafluoropropionyl)-3-(2,2,2-trifluoro-1-trifluoro-methylethyl)urea respectively that result from the rearrangement of the intermediately formed ketone in the process of the intramolecular “haloform” cleavage. At the same time in dioxane the 2,3-epoxyperfluoro-2-methylpentane reacts with urea with the formation of a heterocyclic compound, 2-amino-4-pentafluoroethyl-5,5-bis(trifluoromethyl)-4,5-dihydrooxazol-4-ol. From 1-(2,2,3,3,3-pentafluoropropionyl)-2-(2,2,2-trifluoro-1-trifluoromethylethyl)isothiourea and Cu(OAc)2 a stable fluorine-containing chelate complex was obtained

\\\\Expert2\\nbo\\Russian Journal of Organic Chemistry\\2011, 47 (5), 650-658.pdf
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8.
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    2-Aminooxazoles as novel dienophiles in the inverse demand Diels–Alder reaction with 1,2,4-triazines / A. P. Krinochkin, G. Mallikarjuna Reddy, D. S. Kopchuk [et al.] // Mendeleev Communications. - 2021. - Vol. 31, № 4. - P542-544
ББК Г
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
1,2,4-TRIAZINES -- OXAZOL-2-AMINES -- DIELS–ALDER REACTION -- 2,2'-BIPYRIDIN-3-OLS
Аннотация: High temperature coupling of 6-aryl-5-cyano-3-(pyridin-2-yl)-1,2,4-triazines with 2-amino-4-aryloxazoles proceeds as the inverse demand Diels–Alder reaction between the oxazole moiety as dienophile and the 1,2,4-triazine moiety as diene to construct new 4,5-diaryl-6-cyano-3-hydroxypyridin-2-yl fragment. A reaction mechanism is proposed, and the structure of the key-product is proved by the X-ray diffraction analysis.

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9.
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    2-Azido-5-nitropyrimidine: Synthesis, Molecular Structure, and Reactions with N-, O-, and S-Nucleophiles [Electronic resource] / E. B. Gorbunov, R. K. Novikova, P. V. Plekhanov, P. A. Slepukhin, G. L. Rusinov, V. L. Rusinov, V. N. Charushin, O. N. Chupakhin // Chemistry of Heterocyclic Compounds. - 2013. - Vol.49, №5. - P765-775. - Библиогр.: с. 775 (13 ref.)
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
SYNTHESIS -- 2-AZIDO-5-NITROPYRIMIDINE -- AZIDO-TETRAZOLE TAUTOMERISM
Аннотация: We describe the synthesis of 2-azido-5-nitropyrimidine and its azido-tetrazole tautomerism in various solvents and in the crystalline state. It was established that on interacting with N-nucleophiles the attack occurred at the C-2 carbon atom. The O- and S-nucleophiles attacked C-4 position of pyrimidine ring, resulting in tetrazole ring closure

\\\\expert2\\NBO\\Chemistry of Heterocyclic Compounds\\2013, v.49, N 5, p. 765-775.pdf
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10.
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    2-Hydroxybenzaldehyde (2-phenylquinazolin-4-yl)hydrazones [Electronic resource] / T. V. Trashakhova, E. V. Nosova, P. A. Slepukhin, M. S. Valova, G. N. Lipunova, V. N. Charushin // Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya). - 2011. - Vol.60, №11. - С. 2347-2353. - Bibliogr. : p. 2353 (23 ref.)
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
SALICYLIDENEHYDRAZINE -- ZINC(II) COMPLEXES -- PHOTOLUMINESCENT
Аннотация: N-(2-Phenylquinazolin-4-yl)-N´ salicylidenehydrazines and their ZnII complexes were obtained. The structures and luminescent properties of these new quinazoline derivatives were examined

\\\\expert2\\NBO\\Russian Chemical Bulletin\\2011, 60 (11), 2347-2353.pdf
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11.
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    3-Phenyl/Pyridinyl Derivatives of Trans-2-(aryl/heteryl)vinyl-3H-quinazolin-4-ones: Synthesis and Fluorescent Properties / E. V. Nosova, T. V. Stupina, G. N. Lipunova, M. S. Valova, P. A. Slepukhin, V. N. Charushin // International Journal of Organic Chemistry. - 2012. - Vol.2, №1. - С. 56-63. - Bibliogr.: p. 61-63 (28 ref.)
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
STYRYL BENZAZINES -- X-RAY -- FL SPECTRA

\\\\expert2\\NBO\\International Journal of Organic Chemistry\\2012. v. 2, N 1. P. 56-63.pdf
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12.
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    5-Aryl-2,2-bipyridines as tunable fluorophores [Text] / D. N. Kozhevnikov, O. V. Shabunina, D. S. Kopchuk, P. A. Slepukhin, V. N. Kozhevnikov // Tetrahedron Letters. - 2006. - Vol. 47, № 39. - P7025-7029
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Аннотация: Readily available 5-aryl-2,2?-bipyridines and their derivatives are a unique family of fine-tunable chromophores, where changes in the substitution patterns, solvation and coordination are translated into dramatic spectral changes. They exhibit sensitive and selective response to zinc ions with dramatic increases in emission intensity or significant red-shifts of emission maxima????

\\\\Expert2\\nbo\\Tetrahedron Letters\\2006, v. 47, p.7025.pdf
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13.
Инвентарный номер: нет.
   
   Д 26


   
    9-Allyl-1,7-dicarbadodecaborane as a dienophile in aza Diels-Alder reactions of 1,2,4-triazines: synthesis of pyridines bearing a carborane cage [Electronic resource] / A. M. Prokhorov, P. A. Slepukhin, V. L. Rusinov, V. N. Kalinin, D. N. Kozhevnikov // Tetrahedron Letters. - 2008. - Vol. 49, № 23. - P3785-3789
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
TRIAZINES -- PYRIDINES
Аннотация: The synthesis of pyridine and bipyridine derivatives of m-carborane via aza Diels–Alder reaction of 1,2,4-triazines with 9-allyl m-carborane and their structural characterization and photophysical properties are described. The products 3- and 4-(m-carborane-9-ylmethyl)-2,2`-bipyridines form Zn(II) complexes on reaction with ZnCl2, which increases significantly their fluorescence intensity.

\\\\Expert2\\nbo\\Tetrahedron Letters\\2008, v. 49, p.3785.pdf
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14.
Инвентарный номер: нет.
   
   A 10


   
    A catalyst and additive-free three-component reaction of highly electrophilic azides with cyclic ketones and cycloaliphatic amines. Synthesis of novel N-heteroaryl amidines [Electronic resource] / I. Efimov, N. Beliaev, T. Beryozkina, P. A. Slepukhin, V. A. Bakulev // Tetrahedron Letters. - 2016. - Vol. 57, № 18. - С. 1949-1952
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
SULFONYL AMIDINES; -- KETENE N,X-ACETALS -- CYCLOADDITION REACTIONS
Аннотация: Highly electrophilic 5-azido-1-methyl-4-nitro-1H-imidazole and sulfonyl azides were demonstrated to react with alicyclic amines and cyclic ketones in the absence of any catalyst or additive to afford novel N-(4-nitroimidazol-5-yl)- or N-sulfonylamidines respectively. Based on single crystal X-ray analysis, a revision of the previously reported data of Gao and co-workers on the direction of the reaction of sulfonyl azides with endocyclic enamines was made. The reaction of 2,6-diazidopyridine with an enamine, 4-(cyclohex-1-en-l-yl)morpholine, proceeded with cyclization of the azide moiety onto the pyridine C=N bond to form an amidine bearing the tetrazolo[1,5-a]pyridine fragment.

\\\\expert2\\NBO\\Tetrahedron Letters\\2016, v. 57, p. 1949.pdf
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15.
Инвентарный номер: нет.
   
   A 10


   
    A concise approach to CF3-containing furan-3-ones, (bis)pyrazoles from novel fluorinated building blocks based on 2,3-butanedione [Electronic resource] / D. N. Bazhin, G. -V. Roeschenthaler, D. L. Chizhov, Yu. S. Kudyakova, Ya. V. Burgart, P. A. Slepukhin, V. I. Saloutin, V. N. Charushin // Tetrahedron Letters. - 2014. - Vol. 55. - С. 5714-5717. - Bibliogr. : p. 5717 (16 ref.)
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
ClISEN CONDENSATION -- AKOXYENONES; -- TRIFLUOROACETYLATION
Аннотация: 1,1,1-Trifluoro-4,5,5-trimethoxyhex-3-en-2-one and lithium (2Z)-1,1,1-trifluoro-5,5-dialkoxy-4-oxohex-2-en-2-olate were synthesized for the first time via direct trifluoroacetylation of 2,3-butanedione acetal derivatives. A simple and effective approach to acetal or acyl substituted CF3-pyrazoles, 5,5′-bis(trifluoromethyl)-3,3′-bipyrazole, and, to 5-trifluoromethylfuran-3-ones is presented.

\\\\expert2\\nbo\\Tetrahedron Letters\\2014, v. 55, p. 5714.pdf
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16.
Инвентарный номер: нет.
   
   A 10


   
    A Convenient Approach to CF3-Containing N-Heterocycles Based on 2-Methoxy-2-methyl-5-(trifluoromethyl)furan-3(2H)-one [Electronic resource] / D. N. Bazhin, Yu. S. Kudyakova, G. -V. Roeschenthaler, Ya. V. Burgart, P. A. Slepukhin, M. L. Isenov, V. I. Saloutin, V. N. Charushin // European Journal of Organic Chemistry. - 2015. - № 23. - С. 5236-5245. - Bibliogr. : p. 5245 (23 ref.)
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
NITROGEN HETEROCYCLES -- FLUORINE -- OXYGEN HETEROCYCLES
Аннотация: New synthetic routes to trifluoromethylated N-heterocycles based on condensations of 2-methoxy-2-methyl-5-(trifluoromethyl)furan-3(2H)-one with bifunctional N-nucleophiles are described. For the first time, trifluoromethyl-containing pyrazoles, pyrazolines and isoxazolines bearing hydrazone or oxime groups could be obtained by a one-pot strategy based on reactions of 5-(trifluoromethyl)furan-3(2H)-one with two equivalents of the corresponding hydrazines or hydroxylamine in the presence of an acid. The interaction of furan-3(2H)-one with ureas proceeded under mild conditions to furnish 1H-furo[2,3-d]imidazol-2(3H)-one derivatives in good yield. Further, a trifluoromethyl-containing quinoxaline derivative was obtained by condensation of furan-3(2H)-one with ortho-phenylenediamine.

\\\\expert2\\nbo\\European Journal of Organic Chemistry\\2015, №23. p.5236-5245.pdf
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17.
Инвентарный номер: нет.
   
   A 10


   
    A convenient approach to the design and synthesis of indolo[3,2-c]coumarins via the microwave-assisted Cadogan reaction [Electronic resource] / R. A. Irgashev, A. A. Karmatsky, P. A. Slepukhin, G. L. Rusinov, V. N. Charushin // Tetrahedron Letters. - 2013. - Vol.54, №42. - С. 5734-5738. - Bibliogr. : p. 5738 (17 ref.)
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
COUMARINS -- MICROWAVE-ASSISTED -- CADOGAN REACTION
Аннотация: 3-(4,5-Dimethoxy-2-nitrophenyl)coumarins bearing various substituents on the benzene ring of the coumarin system have been prepared from salicylaldehydes and 2-(4,5-dimethoxy-2-nitrophenyl)acetonitrile by means of the Perkin condensation. Further cyclization of these 3-aryl coumarins through the microwave-assisted Cadogan reaction afforded the corresponding indolo[3,2-c]coumarins in good to excellent yields

\\\\expert2\\NBO\\Tetrahedron Letters\\2013, v. 54, p. 5734.pdf
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18.
Инвентарный номер: нет.
   
   A 10


   
    A facile, metal-free, oxidative coupling of new 6-(hetero)aryl-[1,2,5]oxadiazolo[3,4-b]pyrazines with pyrroles, indoles and carbazoles. / Yu. A. Kvashnin, N. A. Kazin, E. V. Verbitskiy, T. S. Svalova, A. V. Ivanova, A. Kozitsina, P. A. Slepukhin, G. L. Rusinov, O. N. Chupakhin, V. N. Charushin // ARKIVOC. - 2016. - Vol. V. - С. 279-300. - Bibliogr. : p. 297-300 (45 ref.)
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
PYRAZINES -- PYRROLES -- INDOLES

\\\\expert2\\NBO\\ARKIVOC\\2016, p.279-300.pdf
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19.
Инвентарный номер: нет.
   
   A 10


   
    A new approach to incorporate the carboranyl fragment into 2,5-diazabicyclo[2.2.2]oct-2-enes [Electronic resource] / G. L. Rusinov, E. V. Verbitskiy, P. A. Slepukhin, O. N. Zabelina, I. N. Ganebnuikh, V. N. Kalinin, V. A. Ol'shevskaya // Mendeleev Communications. - 2009. - Vol. 19, № 5. - P243-245
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Аннотация: 5-(Het)aryl-2,3-dicyano-1-ethylpyrazinium salts have been established to react with 9-allyl-ortho- and 9-allyl-meta-carboranes in the presence of sodium iodide into carboranylmethyl derivatives of 2,5-diazabicyclo[2.2.2]oct-2-ene

\\\\Expert2\\nbo\\Mendeleev Communications\\2009, v.19, p.243.pdf
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20.
Инвентарный номер: нет.
   
   A 10


   
    A novel transformation of b-1,2,3-thiadiazol-5-yl enamines into thieno[2,3-d]pyridazines / Yu. Rozin, S. Zhidovinov, T. Beryozkina, Yu. Shafran, G. Lubec, O. S. Eltsov, P. A. Slepukhin, W. Dehaen, V. A. Bakulev // Tetrahedron Letters. - 2015. - Vol. 56. - С. 1545-1547
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
B-1,2,3-THIADIAZOL-5-YL ENAMINES -- ENAMINES -- PYRIDAZINES

\\\\expert2\\NBO\\Tetrahedron Letters\\2015, v. 56, p. 1545.pdf
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