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1.
Инвентарный номер: нет.
   


   
    Subsequence nucleophilic functionalisation in the synthesis of arylthiofluorinated imidazoles / N. F. Vaskina, E. A. Nikiforov, T. D. Moseev [et al.] // Modern synthetic methodologies for creating drugs and functional materials (MOSM 2023) : book of abstracts of the 7th International conference. - Perm, 2023. - P223
Рубрики: ХИМИЧЕСКИЕ НАУКИ

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2.
Инвентарный номер: нет.
   


    Joy, M. N.
    Suzuki coupling in water: facile synthesis of novel coumarins / M. N. Joy, G. V. Zyryanov, S. Santra // Modern synthetic methodologies for creating drugs and functional materials (MOSM 2023) : book of abstracts of the 7th International conference. - Perm, 2023. - С. 72
Рубрики: ХИМИЧЕСКИЕ НАУКИ

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3.
Инвентарный номер: нет.
   


    Verbitskiy, E. V.
    SN H-reactions and other cross-dehydrogenative coupling processes for the construction of 1,3-/1,4-diazine-based polycyclic systems / E. V. Verbitskiy, G. L. Rusinov, V. N. Charushin // Physics and chemistry of elementary chemical processes : вook of Abstracts Proceedings of the 10th International Voevodsky Conference. - Novosibirsk, 2022. - P206
Рубрики: ХИМИЧЕСКИЕ НАУКИ

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4.
Инвентарный номер: нет.
   
   E 27


   
    Effect of a New Class of Compounds of the Group of Substituted 5R1, 6H2-1,3,4-thiadiazine-2-amines on the Inflammatory and Cytokine Response in Experimental Myocardial Infarction [Electronic resource] / A. Sarapultsev, O. N. Chupakhin, P. Sarapultsev, M. Rantsev, S. Medvedeva, L. P. Sidorova // Current Vascular Pharmacology. - 2015. - Vol. 13, № 1. - С. 43-53
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
CYTOKINES -- MYOCARDIAL INFARCTION -- L-17 COMPOUND
Аннотация: This study investigated the effects of the L-17 compound of the group of substituted 5R1, 6H2-1,3,4-thiadiazine-2-amines on the immune response and the plasma level of circulating cytokines in acute myocardial infarction (MI) in rats. The study was based upon experimental work which demonstrated the role of local and systemic inflammatory reactions in MI. Acute MI in rats was induced by left coronary artery coagulation. Histological study of the myocardium sections has been carried out at the 1st and 7th days of the experimental myocardial infarction. Serum activity of creatine phosphokinase (CPK), aspartate aminotransferase (AST), isoenzymes 1 and 2 and lactate dehydroge nase (LDH1-2) were investigated at days 1 and 7. ELISA analysis for plasma cytokine levels was performed using commercially available test kits following the manufacturer's instructions. Biochemical analysis in animals with the administration of the L-17 compound after MI showed that the AST and CPK levels at days 5 and 7 of experiments did not differ significantly from the values of intact animals. In animals of the group with MI without the administration of the L-17 compound, the IL-1 level 8 times and the TNF level 7.8 times exceeded the normal indicators, while the use of L-17 compound in the therapy resulted in only 1.8 times increase of IL-1 level and 4.7 times increase of TNF level in comparison with the norm. Thus, the introduction of L-17 compound in case of experimental MI delays exudative/alternative phase of inflammation, accelerates granulocytic and decreased the inflammation and anti-inflammation interleukins level.

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5.
Инвентарный номер: нет.
   
   E 27


   
    Effect of a New Class of Compounds of the Group of Substituted 5R1, 6H2-1,3,4-thiadiazine-2-amines on the Inflammatory and Cytokine Response in Experimental Myocardial Infarction - See more at: http://www.eurekaselect.com/109541/article#sthash.ffuxVde4.dpuf [Electronic resource] / A. Sarapultsev, O. N. Chupakhin, P. Sarapultsev, M. Rantsev, S. Medvedeva, L. P. Sidorova, I. Danilova // Current Vascular Pharmacology. - 2015. - Vol. 13, № 1. - С. 43-53
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
CYTOKINES -- MYOCARDIAL INFARCTION -- L-17 COMPOUND -- INFLAMMATION
Аннотация: This study investigated the effects of the L-17 compound of the group of substituted 5R1, 6H2- 1,3,4-thiadiazine-2-amines on the immune response and the plasma level of circulating cytokines in acute myocardial infarction (MI) in rats. The study was based upon experimental work which demonstrated the role of local and systemic inflammatory reactions in MI. Acute MI in rats was induced by left coronary artery coagulation. Histological study of the myocardium sections has been carried out at the 1th and 7th days of the experimental myocardial infarction. Serum activity of creatine phosphokinase (CPK), aspartate aminotransferase (AST), isoenzymes 1 and 2 and lactate dehydroge nase (LDH1-2) were investigated at days 1stand 7th. ELISA analysis for plasma cytokine levels was performed using commercially available test kits following the manufacturer's instructions. Biochemical analysis in animals with the administration of the L-17 compound after MI showed that the AST and CPK levels at days 5 and 7 of experiments did not differ significantly from the values of intact animals. In animals of the group with MI without the administration of the L-17 compound, the IL-1 level 8 times and the TNF level 7.8 times exceeded the normal indicators, while the use of L-17 compound in the therapy resulted in only 1.8 times increase of IL-1 level and 4.7 times increase of TNF level in comparison with the norm. Thus, the introduction of L-17 compound in case of experimental MI delays exudative/alternative phase of inflammation, accelerates granulocytic and decreased the inflammation and anti-inflammation interleukins level. - See more at: http://www.eurekaselect.com/109541/article#sthash.ffuxVde4.dpuf

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6.
Инвентарный номер: нет.
   
   S 98


   
    Synthesis of new C(4) and/or C(5) thienyl substituted pyrimidines as potential antimycobacterial agents. / E. V. Verbitskiy, E. M. Cheprakova, M. A. Kravchenko, S. N. Skornyakov, G. L. Rusinov, O. N. Chupakhin, V. N. Charushin // 19h European Symposium on Organic Chemistry (ESOC-2015), 12th-16th July, Lisboa, Portugal, 2015. : book of abstr. . - Lisboa, 2015. - С. 450
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
PYRIMIDINES -- ANTIMYCOBACTERIAL AGENTS -- SYNTHESIS

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7.
Инвентарный номер: нет.
   
   C 73


   
    Combination of the SNH reaction, Suzuki cross-coupling and photocyclization as a versatile strategy for construction of new polycyclic systems on the basis of the pyrimidine scaffold / E. M. Cheprakova, E. V. Verbitskiy, G. L. Rusinov, O. N. Chupakhin, V. N. Charushin // 19h European Symposium on Organic Chemistry (ESOC-2015), 12th-16th July, Lisboa, Portugal, 2015. : book of abstr. . - Lisboa, 2015. - С. 196
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
SNH REACTIONS -- SUZUKI CROSS-COUPLING -- PHOTOCYCLIZATION

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8.
Инвентарный номер: нет.
   
   S 98


   
    Synthesis and solar light catalytic properties of the titania-sulfide hybrid nanostructures / A. A. Rempel, E. A. Kozlova, T. I. Gorbunova, S. V. Cherepanova, E. Yu. Gerasimov, A. A. Valeeva, E. Yu. Korovin, S. V. Tsybulya, Ya. A. Shchipunov // 8th European Meeting on Solar Chemistry and Photocatalysis: Environmental Applications – SPEA8, Thessaloniki, 25-28 June 2014 : book of abstr. - Thessaloniki, 2014. - P. 62
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
CATALYTIC PROPERTIES -- TITANIA-SULFIDE HYBRID NANOSTRUCTURES

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9.
Инвентарный номер: нет.
   
   N 89


   
    Novel catalytic systems containing metal nanooxides for assymetric Biginelli reaction / Yu. A. Titova, O. V. Fedorova, A. Yu. Vigorov, V. P. Krasnov, I. V. Krivtsov, A. Murashkevich, G. L. Rusinov, V. N. Charushin // 8-th Eurasian meeting on heterocyclic chemistry (EAMHC-2014) : book of abstr., Tbilisi, Georgia. - Tbilisi, 2014. - P. 157
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
METAL NANOOXIDES -- BIGINELLI REACTION

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10.
Инвентарный номер: нет.
   
   S 98


   
    Synthesis and solar light catalytic properties of the titania-sulfide hybrid nanostructures / A. A. Rampel, E. A. Kozlova, T. I. Gorbunova, S. V. Cherepanova, E. Yu. Gerasimov, A. A. Valeeva, E. Yu. Korovin, S. V. Tsybulya, Ya. A. Shchipunov // 8-th European Meeting on Solar Chemistry and Photocatalysis: Environmental Applications - SPEA 8, Saloniki, 25-28 June 2014 : abstracts. - Saloniki : Aristotle University of Thessloniki, 2014. - С. 62
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
SYNTHESIS -- NANOSIZED METAL OXIDES -- TITANIUM DIOXIDE

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11.
Инвентарный номер: нет.
   
   P 80


   
    Polyfluoroacyl pyruvaldehyde dimethylacetal – a novel fluorinated building-block for design of verdazyl radicals / D. L. Chizhov, D. V. Belyaev, D. S. Yachevskii, G. L. Rusinov, O. N. Chupakhin, V. N. Charushin // The 14th International Conference on Molecule-Based Magnets, Saint-Petersburg, Russia, July 5-9 2014. : book of abstr. . - SPb, 2014. - P-621
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
POLYFLUOROACYL PYRUVALDEHYDE DIMETHYLACETAL -- BUILDING-BLOCK -- VERDAZYL RADICALS

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12.
Инвентарный номер: нет.
   
   M 78


   
    Modulation of inflammatory response improves myocardial infarct healing in rats / A. Sarapultsev, O. N. Chupakhin, P. Sarapultsev, M. T. Abidov, I. Danilova // Current Pharmaceutical Design . - 2014. - Vol.20, №12. - С. 1980-1986
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
INFLAMMATION -- L-17 COMPOUND -- MYOCARDIAL INFARCTION
Аннотация: It is reputed that the ideal therapeutic approaches to treatment of patients with acute coronary syndrome (ACS) and myocardium infarction (MI) should be aimed at the inflammation reaction triggers. This study investigated the effectiveness of the impact of L-17 compound of the group of 5- phenyl substituted-6H-1,3,4-thiadiazine-2-amines upon the course of experimental MI as compared to the impact of a preparation, officially registered in Russia as an immunomodulator, Tamerit, belonging to phthalhydrazid derivative substance. Acute MI in rats was induced by left coronary artery coagulation. Histological study of the myocardium sections and biochemical analysis has been carried out at the 1st and 7th days of the experimental MI. The conducted investigations have shown that under the action of immunocorrectors the inflammation reaction character changes, exudative/destructive inflammation is replaced by a proliferative-cellular one. Animals' blood biochemical analysis at the background of L-17 and Tamerit introduction has shown a decrease of aminotransferases and lactatedehydrogenases activity in blood as compared to the reference group of animals' indicators, which is evidently caused by epicardial injury of myocardium and lesser amount of the alternative cardiomyocytes. At the same time, no noticeable difference in biochemical characteristics in groups, having been treated to immunomodulators of different chemical composition was identified, which is the sign of the essential similarity of their impact. Thus, immunocorrectors of different chemical groups (Tamerit and compound L17) diminish the volume of initial myocardial infarction and accelerate the granulation processes in course of MI, and represent a new category of treatment agents

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13.
Инвентарный номер: нет.
   
   L 62


    Levit, G. L.
    Acylative kinetic resolution with chiral acyl chlorides as an efficient preparative approach for enantio pure heterocyclic amines / G. L. Levit, V. P. Krasnov // CHIRALITY 2014. 26-th International Symposium on Chiral Discrimination, ISCD-26, Prague, Czech Repablic, 27-30 July 2014 : book of asbstracts. - Prague, 2014. - 218 (P-099). - Bibliogr. : p. 218 (2 ref.)
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
HETEROCYCLIC AMINES -- RESOLVING AGENTS -- SYNTHESIS

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14.
Инвентарный номер: нет.
   
   P 80


   
    Polyfluoroacyl pyruvaldenyde dimetihylacetal - a novei fluorinated building-block for design of verdazyl radicals / D. L. Chizhov, D. V. Belyaev, D. S. Yachevskii, G. L. Rusinov, O. N. Chupakhin, V. N. Charushin // The 14-th International Conference of Molecule-based Magnets : absr. book, Saint Petersburg, Russia, July 5-10 2014. - СПб., 2014. - P-621. - С. 122. - Bibliogr. : p. 122 (3 ref.)
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
VERDAZYL RADICALS -- HETEROCYCLES

\\\\expert2\\NBO\\The 14-th International Conference of Molecule-based Magnets\\The 14-th International Conference of Molecule-based Magnets.pdf
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15.
Инвентарный номер: нет.
   
   N 89


   
    Novel cataytic systems containing metal nanooxides for asymmetric biginelli reactions / Yu. A. Titova, O. V. Fedorova, A. Yu. Vigorov, V. P. Krasnov, I. V. Krivtsov, A. Murashkevich, G. L. Rusinov, V. N. Charushin // 8-th Eurasian meeting on heterocyclic chemistry (EAMHC), Tbilisi, Georgia, 20-24 september 2014. - Tbilisi, 2014. - С. 157-159. - Bibliogr. : p. 159 (7 ref.)
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
NANOOXIDE -- HETEROCYCLIC SYSTEMS -- BIGINELLI REACTION

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16.
Инвентарный номер: нет.
   
   T 82


   
    Transformations of 2-azido-5-nitropyrimidine in reactions wirh pyridinium ylides / E. B. Gorbunov, G. L. Rusinov, O. N. Chupakhin, V. N. Charushin // 8-th Eurasian meeting on heterocyclic chemistry (EAMHC), Tbilisi, Georgia, 20-24 september 2014. - Tbilisi, 2014. - С. 174-715
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
NITROAINES -- NUCLEOPHILIC ATTACK -- RECYCLIZATION

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17.
Инвентарный номер: нет.
   


   
    2-Pyridoyltrifluoroacetyl acetone in synthesis of 3d-4f complexes [Co-2(II)Ln-2(III)(L)-8(OH)-2] with dicubane structure / D. L. Chizhov, D. S. Yachevskii, N. S. Boltacheva, V. I. Filyakova, O. N. Chupakhin, V. N. Charushin // The 14-th International Conference of Molecule-based Magnets : absr. book, Saint Petersburg, Russia, July 5-10 2014. - СПб., 2014. - P-622. - С. 123
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
3d-4f COMPLEXES -- 2-PYRIDOYLTRIFLUOROACETYL ACETONE

\\\\expert2\\NBO\\The 14-th International Conference of Molecule-based Magnets\\The 14-th International Conference of Molecule-based Magnets.pdf
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18.
Инвентарный номер: нет.
   
   M 17


   
    Magnetic properties of single-molecule magnets [Me-2(II)Fe-2(III)(L)-4(OH)-2(EtOH)-2 (Et-2OH)-2] Me = Co, NI with dicubane structure / D. L. Chizhov, P. A. Slepukhin, D. S. Yachevskii, V. N. Charushin // The 14-th International Conference of Molecule-based Magnets : absr. book, Saint Petersburg, Russia, July 5-10 2014. - СПб., 2014. - P-676. - С. 177. - Bibliogr. : p. 177 (1 ref.)
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
MAGNETIC PROPERTIES -- DICUBANE STRUCTURE

\\\\expert2\\NBO\\The 14-th International Conference of Molecule-based Magnets\\The 14-th International Conference of Molecule-based Magnets.pdf
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19.
Инвентарный номер: нет.
   
   I-55


   
    Immunotropic drugs for local use in stomatology [Electronic resource] / G. I. Ron, I. N. Shtanko, T. G. Khonina, I. A. Tuzankina, A. S. Simbirtsev // Materials of 15th International Congress of Immunology (ICI). - Milan, 2013
ББК 61
Рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ
Кл.слова (ненормированные):
STOMATOLOGY -- IMMUNOTROPIC DRUGS

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20.
Инвентарный номер: нет.
   
   S 98


   
    Synthesis of New Acyclovir Analogues Based on 1,2,4-Triazolo[1,5-a]pyrimidin-7-ones. / T. S. Sheshukova, I. A. Khalymbadzha, V. L. Rusinov, O. N. Chupakhin, I. L. Karpenko, M. V. Yasko, M. K. Kukhanova, S. L. Deev // 18th European Symposium on Organic Chemistry ESOC-2013, Marseille, France, 7-12 July 2013 : book of abstracts. - Marseille, France, 2013. - С. 167
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
SYNTHESIS -- ACYCLOVIR ANALOGUES -- PYRIMIDINE

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