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 1-10    11-21   21-21 
1.
Инвентарный номер: нет.
   
   T 44


   
    The elaboration of New Elementorganic Hydrogels for Pharmaceutical Compositions of Local and External Application: the 3rd China-Russia international symposium on pharmacology [Text] : доклад, тезисы доклада / L. P. Larionov, T. G. Khonina, P. V. Sorokin, E. V. Shadrina, A. A. Boyko, N. A. Zabokritskii, G. B. Philippova, O. N. Chupakhin // Pharmacology. - Harbin : Harbin medical university, 2008. - P4-5
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
HYDROGELS -- GLYCEROLATES

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2.
Инвентарный номер: нет.
   
   N 52


   
    New Adhesive Composition for Fixation of Removable Dentures [Text] : доклад, тезисы доклада / T. D. Mirsaev, E. V. Shadrina, T. G. Khonina // Pharmacology: the 3rd China-Russia International symposium on pharmacology. - Harbin : Harbin medical university, 2008. - P19-20
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ

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3.
Инвентарный номер: нет.
   
   S 98


   
    Synthesis and biological activity of organosilicontitanium glycerohydrogels [Electronic resource] / T. G. Khonina, O. N. Chupakhin, L. P. Larionov, P. V. Sorokin, N. A. Zabokritskii, A. L. Suvorov, E. V. Shadrina, M. V. Ivanenko // Pharmaceutical Chemistry Journal. - 2009. - Vol. 43, № 2. - P95-100
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Аннотация: A series of organosilicontitanium (OST) glycerohydrogels with the general formula 2Si(C3H7O3)4 Ti(C3H7O3)4 xC3H8O3 yH2O (where 9 x 30 and 60 y 120) were synthesized and some of their pharmacological properties were studied. High percutaneous activity of the compounds was revealed by measuring the diffusion of sodium diclofenac through intact skin membranes in vitro. It was established that all of the synthesized substances are nontoxic. The wound-healing and antioxidant properties of the glycerohydrogels were studied. The experimental results show that OST glycerohydrogels can be recommended for further testing as effective percutaneous vehicles of medicines with wound-healing, burn-healing, and antioxidant action

\\\\Expert2\\nbo\\Pharmaceutical Chemistry Journal\\2009, 43 (2), 95.pdf
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4.
Инвентарный номер: нет.
   
   S 98


   
    Synthesis of hydrogels based on silicon polyolates [Electronic resource] / T. G. Khonina, E. V. Shadrina, A. A. Boyko, O. N. Chupakhin, L. P. Larionov, A. A. Volkov, V. D. Burda // Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya). - 2010. - Vol. 59, № 1. - P75-80
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
ORGANOSILICON COMPOUNDS -- DIOLS -- GLYCEROL
Аннотация: Biologically active hydrogels based on silicon polyolates, which are the products of reactions of tetraethoxy- and methyltriethoxysilanes with polyols (1,2-propanediol, glycerol, polyethylene glycol), were synthesized. The optimal conditions for hydrogel formation and hydrogel composition were determined. The acute toxicity and transcutaneous and wound-healing activities of the synthesized compounds were studied. The experimental results show that hydrogels based on silicon polyolates can be recommended for further preclinical and clinical tests with the purpose of their use in medical practice both as self-sufficient agents and ointment bases of pharmaceutical compositions with wound-healing, regenerative, and transcutaneous action

\\\\Expert2\\nbo\\Russian Chemical Bulletin\\2010, 59 (1), 75-80.pdf
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5.
Инвентарный номер: нет.
   
   S 85


   
    Stnthesis, toxicity, and percutaneous activity of silicon glycerolates and related hydrogels [Electronic resource] / T. G. Khonina, O. N. Chupakhin, L. P. Larionov, T. G. Boyakovskaya, A. L. Suvorov, E. V. Shadrina // Pharmaceutical Chemistry Journal. - 2008. - Vol. 42, № 11. - P609-613 : il. - Bibliogr. : p. 612 (12 ref.)
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
SILICON -- SILICON GLYCEROLATES -- HYDROGELS -- SYNTHESIS -- TOXICITY -- PERCUTANEOUS ACTIVITY

\\\\Expert2\\nbo\\Pharmaceutical Chemistry Journal\\2008, 42 (11), 609.pdf
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6.
Инвентарный номер: нет.
   
   O-72


   
    Organosilicontitanium glycerohydrogels are the new base of topical phermaceutical composition [Text] : доклад, тезисы доклада / T. G. Khonina, L. P. Larionov, T. G. Boyakovskaya, E. V. Shadrina, A. L. Suvorov // Fundamental pharmacology and pharmacy-clinical practice, Perm, 25-27 September 2006 : materials of 2-nd Russian-Chinese International scientific conference of pharnacology. - Perm, 2006. - P171-172
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
HYDROGELS -- GLYCEROHYDROGELS -- PHARMACEUTICAL COMPOSITION -- OINTMENTS -- MEDICAMENTS

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7.
Инвентарный номер: нет.
   
   O-72


   
    Organosilicontitanium glycerohydrogels are the new base of topical pharmaceutical ompositions [Text] / T. G. Khonina, L. P. Larionov, T. G. Boyakovskaya, E. V. Shadrina, A. L. Suvorov // International conference "Fundamental pharmacology and pharmacy-clinical practice", Perm, 2006. - Perm, 2006. - P171-172
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ

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8.
Инвентарный номер: нет.
   
   C 74


   
    Composition, structure, and properties of pharmacologically active silicon dimethylglycerolates [Electronic resource] / T. G. Khonina, E. Yu. Larchenko, E. V. Shadrina, I. N. Ganebnuikh, A. A. Boyko, E. G. Matochkina, M. I. Kodess, O. N. Chupakhin // Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya). - 2010. - Vol. 59, № 12. - P2230-2235. - Bibliogr. : p. 2235 (13 ref.)
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Аннотация: 1H and 29Si NMR spectroscopy showed that the product of the reaction of dimethyldiethoxysilane with glycerol in the molar ratio 1: 2 is an equilibrium mixture of dimethyldiglyceroxysilane and low-molecular-weight condensation products. The change of viscosity of silicon dimethylglycerolates, synthesized using different excesses of glycerol, versus time was studied by viscosimetry. Composition of products of hydrolysis and condensation of silicon dimethylglycerolates is determined by their concentration in the starting aqueous solutions

\\\\Expert2\\nbo\\Russian Chemical Bulletin\\2010, 59 (12), 2230-2235.pdf
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9.
Инвентарный номер: нет.
   
   M 45


   
    Mechanism of structural networking in hydrogels based on silicon and titanium glycerolates / T. G. Khonina, A. P. Safronov, E. V. Shadrina, M. V. Ivanenko, A. I. Suvorova, O. N. Chupakhin // Journal of Colloid and Intrface Science. - 2012. - Vol. 365, № 1. - С. 81-89
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
HOFMEISTER SERIES -- TITANIUM–GLYCEROL HYDROGELS -- SCHULTZE–HARDY RULE
Аннотация: Formation of organic/inorganic hydrogels based on silicon– and titanium–glycerol precursors synthesized by transesterification of alkoxy derivatives in excess of glycerol was investigated. The precursors in excess of glycerol and obtained gels were studied by chemical and physical methods including gelation kinetics, IR spectroscopy, XRD, dynamic and electrophoretic light scattering, mechanical deformation, which disclosed the basic difference in the gelation mechanism and structure of network in the hydrogels. Due to this difference, the gelation time of silicon– and titanium–glycerol precursors depended on pH or electrolyte addition in an opposite way. In the wide pH range, silicon–glycerol hydrogel was a polymeric single-phase system formed by the polymeric network homogeneously swollen in liquid water/glycerol medium. Flory–Rehner theory applied to the elastic modulus of these gels gave 40–180 monomer base units in the subchains of the network depending on water content in the gel. The mechanism of networking was three-dimensional polycondensation promoted by the electrically charged functional groups attached to the flexible polymeric chains. Electrolyte solutions provided the gelation according to Hofmeister series. Titanium–glycerol hydrogels were heterogeneous colloid systems at pH > 1.5 and single-phase polymeric gels at lower pH. Electrolyte solutions provided the gelation according to Schultze–Hardy rule

\\\\Expert2\\nbo\\Journal of Colloid and Interface Science\\2012, v.365, p.81.pdf
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10.
Инвентарный номер: нет.
   
   N 52


   
    New hybrid chitosan-silicone-containing glycerohydrogels [Electronic resource] / E. Yu. Larchenko, E. V. Shadrina, T. G. Khonina, O. N. Chupakhin // Mendeleev Communications. - 2014. - Vol.24, №4. - С. 201-202. - Bibliogr. : p. 202 (20 ref.)
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
CHITOSAN -- GLYCEROHYDROGELS -- SOL-GEL METHOD
Аннотация: New biologically active hybrid chitosan-silicone-containing glycerohydrogels based on chitosan and silicon glycerolates were synthesized by a sol-gel method; the effect of silicon glycerolates and chitosan concentrations on the process of gel formation was evaluated.

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