R 30 Reactions of 1,2,4-triazin-5(2H)-ones with phenols and aromatic-amines [Text] / O. N. Chupakhin, V. L. Rusinov, D. G. Beresnev, H. Neunhoeffer // Journal of Heterocyclic Chemistry. - 1997. - Vol. 34, N 2. - P573-578 Рубрики: ХИМИЧЕСКИЕ НАУКИ \\\\Expert2\\nbo\\Journal of Heterocyclic Chemistry\\1997.v.34, p.573.Chupakhin.pdf |
Р 25 Ратнер, В. Г. Раскрытие фторалкилсодержащих альфа,бета-эпоксикетонов ароматическими аминами [] = Ring-opening of fluoroalkyl-containing alpha,beta-epoxyketones by aromatic-amines / В. Г. Ратнер, К. И. Пашкевич // Изв. АН. Сер. Химическая. - 1994. - N 5. - С. 882-883 . - ISSN 0002-3353 Рубрики: ХИМИЧЕСКИЕ НАУКИ |
В 40 Взаимодействие фторалкилсодержащих бета-дикетонов с аминами [] = Interaction of fluoroalkyl-containing beta-diketones with amines / В. И. Филякова, В. Г. Ратнер, Н. С. Карпенко, К. И. Пашкевич // Изв. АН. Сер. Химическая. - 1996. - N 9. - С. 2278-2284 . - ISSN 0002-3353 Рубрики: ХИМИЧЕСКИЕ НАУКИ |
В 40 Взаимодействие пентафторбензоилпировиноградной кислоты с аминами [] = Reaction of pentafluorobenzoylpyruvic acid with amines / В. И. Салоутин, И. Т. Базыль, З. Э. Скрябина, П. Н. Кондратьев, О. Н. Чупахин // Изв. АН. Сер. Химическая. - 1994. - N 2. - С. 299-302 . - ISSN 0002-3353 Рубрики: ХИМИЧЕСКИЕ НАУКИ |
Б 79 Болтачева, Н. С. Фторалкилсодержащие 1,3-дикетонаты лития в реакциях с аминами и их солями [] = Fluoroalkyl-containing lithium 1,3-diketonates in reactions with amines and ammonium salts / Н. С. Болтачева, В. И. Филякова, В. Н. Чарушин // Журнал органической химии. - 2005. - Т. 41, N 10. - 1483-1488: рис. - Библиогр. : с. 1488 (16 назв.) . - ISSN 0514-7492 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: Взаимодействие фторалкилсодержащих 1,3-дикетонатов лития с аминами (или солями аминов) в ледяной уксусной кислоте(или метаноле) при 20 град. С является эффективным способом получения фторалкилсодержащих 1,3- аминовинилкетонов. изменяя условия реакций дикетонатов лития с 1-аминонафталином можно получить как 1.3-аминовинилкетоны, так и продукты циклоконденсации - бензо[h]хинолины. Последние могут быть получены в одну стадию без выделения 1,3-аминовинилкетонов. |
M 78 Modeling of 1,2,4,5-tetrazine complexes with organic amines [Electronic resource] / M. A. Grishina, V. A. Potemkin, E. V. Bartashevich, A. N. Sinyaev, G. L. Rusinov, N. I. Latosh, I. N. Ganebnuikh, O. V. Koryakova, R. I. Ishmetova // Journal of Structural Chemistry. - 2006. - Vol. 47, № 6. - P1155-1160 Рубрики: ХИМИЧЕСКИЕ НАУКИ \\\\Expert2\\nbo\\Journal of Structural Chemistry\\2006, V. 47, N 6, p.1155.pdf |
F 70 Fluorine-containing heterocycles. XV. Reactions of polyfluorobenzoyl isothiocyanates with amino azines and amino azoles [Electronic resource] / E. V. Nosova, G. N. Lipunova, A. A. Laeva, V. N. Charushin // Russian Journal of Organic Chemistry (Translation of Zhurnal Organicheskoi Khimii). - 2006. - Vol. 42, № 10. - P1544-1550. - Библиогр. : с. 1550 (9 назв.) Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: Reactions of tetra-and pentafluorobenzoyl isothiocyanates with aminoazoles and aminoazines led to the formation of fluorinated 1,3-benzothiazin-4-ones which reacted with cyclic amines in different ways. Replacement of the N=C=S fragment was observed in some reactions of polyfluorobenzoyl isothiocyanates with nucleophiles. \\\\Expert2\\nbo\\Russian Journal of Organic Chemistry\\2006, 42 (10), 1544.pdf |
F 94 From 3-chloromethyl-1,2,4-triazine 4-oxides to various substituted pyridines and 1,2,4-triazines [Electronic resource] / V. N. Kozhevnikov, D. N. Kozhevnikov, O. V. Shabunina, N. N. Kataeva, S. A. Yushchuk, V. L. Rusinov, O. N. Chupakhin // Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya). - 2005. - Vol. 54, № 9. - P2187-2196. - Библиогр. : с. 2196 (24 назв.) Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: An efficient strategy for the synthesis of new pyridine and 1,2,4-triazine derivatives starting from available 6-aryl-3-chloromethyl-1,2,4-triazine 4-oxides was proposed. The deoxygenative nucleophilic hydrogen substitution in the triazine-oxide ring, nucleophilic substitution of the chlorine atom in the side chain, and transformations of the 1,2,4-triazine ring into the pyridine ring via the inverse-electron-demand Diels-Alder reactions, being used in different orders, are a rather flexible tool for the functionalization of the titled heterocycles. The cyanide anion, indoles, thiophenols, amines, and triphenylphosphine were used as nucleophiles. The direct introduction of indole residues into the 1,2,4-triazine ring followed by the substitution of the chlorine atom by a residue of the primary or secondary aliphatic amine was found to be the most convenient method for the library synthesis. \\\\Expert2\\nbo\\Russian Chemical Bulletin\\2005, 54 (9), 2187-2196.pdf |
S 98 Synthesis of 4-amino derivatives of 5-oxoproline [Text] / V. P. Krasnov, A. Yu. Vigorov, I. A. Nizova, T. V. Matveeva, A. N. Grishakov, I. V. Bazhov, A. A. Tumashov, M. A. Ezhikova, M. I. Kodess // European Journal of Organic Chemistry. - 2007. - № 25. - P4257-4266 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: The possibility of obtaining the stereoisomeric derivatives of 5-oxoproline and glutamic acid with a tertiary amino group at C-4, using the nucleophilic substitution of bromine in dimethyl (2S,4RS)-4-bromo-N-phthaloylglutamate with secondary amines followed by resolution of diastereomers and removal of protecting groups has been studied. We have shown that the reaction with arylamines results in optically pure 5-oxoproline derivatives in high yields. In the case of more basic amines, the reaction is accompanied by racemization, and the target products can be isolated only as diastereomeric racemates. |
N 10 N-Phthaloyl-(S)-alanyl chloride as a chiral resolving agent for the kinetic resolution of heterocyclic amines [Text] / V. P. Krasnov, G. L. Levit, M. I. Kodess, V. N. Charushin, O. N. Chupakhin // Tetrahedron: Asymmetry . - 2004. - Vol. 15, № 5. - P859-862 : ил. - Библиогр.: с. 862 (7 ref.) Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): HETEROCYCLIC AMINES -- CHLORIDE -- KINETIC RESOLUTION Аннотация: Acylation of heterocyclic amines with N-phthaloyl-(S)-alanyl chloride under kinetic resolution conditions resulted in the predominant formation of (S,S)-amides. The diastereoselectivity of resolution depended heavily on the structure of the resolved amine.???? \\\\Expert2\\nbo\\Tetrahedron Asymmetry\\2004, v.15, p.859.pdf |
C 73 Condensation of 2-polyfluoroacycloalkanones with aldehydes and dimethylformamide-dimethylacetal [Text] / D. V. Sevenard, O. G. Khomutov, M. I. Kodess, K. I. Pashkevich, I. Loop, E. Lork, G. -V. Roeschenthaler // Australian Journal of Chemistry. - 2001. - Vol. 54, № 3. - P157-163 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: Polyfluorinated 1,3-diketones containing carbocycles react with aldehydes under Lewis-acid catalysis and also with dimethylformamide-dimetylacetal without catalysis, yielding exclusively (E)-configured condensation products involving the methylene group of the carbocycle. Novel trifluoromethylated chromenes are prepared from 2-trifluoroacetylcycloalkanones and salicylaldehyde. The structures of two new compounds, 2-(E)-benzylidene-6-trifluoroacetylcyclohexanone and 4-trifluoroacetyl-2,3-dihydro-1H-xantene, are confirmed by X-ray structure analysis. |
R 30 Reaction of 5-halo-1,2,3-thiadiazoles with aliphatic diamines. Synthesis and intramolecular cyclization of bis(1,2,3-triazolyl-1,2,3-thiadiazolyl)sulfides [Text] / N. N. Volkova, E. V. Tarasov, M. I. Kodess, L. Van Meerlent, W. Dehaen, V. A. Bakulev // Organic and Biomolecular Chemistry. - 2003. - Vol. 1, № 22. - P4030-4038 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: Bis[1,2,3]triazolo[1,5-f:5?,1?-b][1,3,6]thiadiazepine and [1,5-g:5?,1?-b][1,3,7]thiadiazocine ring systems have been synthesized from 5-halo-1,2,3-thiadiazoles and aliphatic diamines. We have found that the last step of the process is the cyclization of initially formed bis(1,2,3-triazolyl-1,2,3-thiadiazolyl)sulfides. The structures of the intermediates and products were supported by different NMR spectroscopic methods (1H coupled 13C NMR, 2D HETCOR, HMBC and 1D INADEQUATE experiments) and mass spectrometry. Differences in the reaction pathway for aliphatic and less nucleophilic aromatic diamines were determined. |
K 46 Kinetic resolution of (±)-2-methyl-1,2,3,4-tetrahydroquinoline and (±)-2-methylindoline [Electronic resource] / V. P. Krasnov, G. L. Levit, I. N. Andreeva, A. N. Grishakov, V. N. Charushin, O. N. Chupakhin // Mendeleev Communications. - 2002. - Vol. 12, № 1. - P27-28 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: The acylation of racemic 2-methyl-1,2,3,4-tetrahydroquinoline and 2-methylindoline by (S)-naproxen acyl chloride resulted in their kinetic resolution with the predominant formation of (S,S)-diastereoisomeric amides (de 78–76%), recrystallisation of which followed by acid hydrolysis gave individual (S)-isomers of heterocyclic amines???? \\\\expert2\\nbo\\Mendeleev Communications\\2002, v.12, N 1. p.27.pdf |
K 46 Kinetic resolution of (±)-2,3-dihydro-3-methyl-4H-1,4-benzoxazine, (±)-2-methyl-1,2,3,4-tetrahydroquinoline and (±)-2-methylindoline using N-tosyl-(S)-prolyl chloride [Text] / V. P. Krasnov, G. L. Levit, I. M. Bukrina, I. N. Andreeva, L. Sh. Sadretdinova, M. A. Koroleva, M. I. Kodess, V. N. Charushin, O. N. Chupakhin // Tetrahedron: Asymmetry . - 2003. - Vol. 14, № 14. - P1985-1988. - Bibliogr. : p. 1988 (6 ref.) Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: Acylation of racemic 2,3-dihydro-3-methyl-4H-1,4-benzoxazine, 2-methyl-1,2,3,4-tetrahydroquinoline and 2-methylindoline with N-tosyl-(S)-prolyl chloride resulted in their kinetic resolution with the predominant formation of (R,S)-diastereoisomeric amides, des being 80, 66 and 38%, respectively. Recrystallisation of the amides followed by acid hydrolysis gave individual (R)-enantiomers of heterocyclic amines \\\\Expert2\\nbo\\Tetrahedron Asymmetry\\2003, v.14, p.1985.pdf |
B 62 Bis[N-(2-hydroxyethyl)-beta-alaninato]-copper(II) [Text] / A. V. Pestov, E. V. Peresypkina, A. V. Virovets, N. V. Podberezskaya, Yu. G. Yatluk, Yu. A. Skorik // Acta Crystallographica Section C: Crystal Structure Communications. - 2005. - Vol. 61, № 12. - Pm510-m512 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: The CuII ion in the title complex, [Cu(C5H 10NO3)2] or [Cu(He-ala)2] [He-ala = W-(2-hydroxyethyl)-?-alaninate], resides at the inversion centre of a square bipyramid comprised of two facially arranged tridentate He-ala ligands. Each He-ala ligand binds to a CuII ion by forming one six-membered ?-alaninate chelate ring in a twist conformation and one five-membered ethanolamine ring in an envelope conformation, with Cu-N = 2.017 (2) A, Cu-OCoo = 1.968 (1) A and Cu-OOH = 2.473 (2) A. The [Cu(He-ala)2] molecules are involved in a network of O-H?O and N-H?O hydrogen bonds, forming layers parallel to the (101?) plane. The layers are connected into a three-dimensional structure by van der Waals interactions, so that the molecular centres form pseudo-face-centered close packing. © 2005 International Union of Crystallography???? |
A 10 A simple and convenient synthesis of 4-methyl-3-nitro-2-trihalomethyl-2H-chromenes from N-unsubstituted imines of 2-hydroxyacetophenones and trichloro(trifluoro)ethylidene nitromethanes [Text] / V. Yu. Korotaev, V. Ya. Sosnovskikh, I. B. Kutyashev, A. Yu. Barkov, E. G. Matochkina, M. I. Kodess // Tetrahedron. - 2008. - Vol. 64, № 22. - P5055-5060 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: The reaction of N-unsubstituted imines of 2-hydroxyacetophenones with trichloro(trifluoro)ethylidene nitromethanes in the presence of DABCO proceeds via tandem oxa-Michael/aza-Henry additions (in dichloromethane) or aza-Michael addition (in benzene) to give 4-methyl-3-nitro-2-trichloro(trifluoro)methyl-2H-chromenes or 1,1,1-trichloro(trifluoro)-3-nitro-N-[1-(2-hydroxyaryl)ethylidene]propan-2-amines, respectively???? \\\\Expert2\\nbo\\Tetrahedron\\2008, v. 64, N22, p. 5050.pdf |
S 73 Sosnovskikh, V. Ya. Structural revision in the reactions of 3-cyanochromones with primary aromatic amines. Improved synthesis of 2-amino-3-(aryliminomethyl)chromones [Text] / V. Ya. Sosnovskikh, V. S. Moshkin, M. I. Kodess // Tetrahedron Letters. - 2009. - Vol. 50, № 47. - P6515-6518 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: 3-Cyanochromones react with primary aromatic amines to give 2-amino-3-(aryliminomethyl)chromones as the sole products or as their mixtures with Z- and E-3-anilino-2-salicyloylacrylonitriles, depending on the reaction conditions. With aliphatic amines, 2-amino-3-(alkyliminomethyl)chromones are obtained in good yields. The reaction of 3-cyanochromone with o-phenylenediamine is reinvestigated and proof for the product structure and a possible reaction pathway are presented \\\\Expert2\\nbo\\Tetrahedron Letters\\2009, v. 50, p.6515.pdf |
K 46 Kinetic resolution of Heterocyclic Amines using N-Tosyl-(S)-prolyl chloride [Text] : доклад, тезисы доклада / V. N. Charushin, V. P. Krasnov, G. L. Levit, I. N. Andreeva, I. M. Bukrina // XXth European Colloquium on Heterocyclic Chemistry, Stockholm,Sweden, 18-21 Aug. 2002 г. - Stockholm, 2002. - PA:7 Рубрики: ХИМИЧЕСКИЕ НАУКИ |
A 10 A new family of Chromophores based on 2-pyridines and oxazoles for the off-resonant optical kerr effect [Text] : доклад, тезисы доклада / O. N. Chupakhin, G. L. Rusinov, D. G. Beresnev, N. A. Itsikson, I. G. Ovchinnikova, O. V. Fedorova // XXth European Colloquium on Heterocyclic Chemistry, Stockholm,Sweden, 18-21 Aug. 2002 г. - Stockholm, 2002. - PG:1 Рубрики: ХИМИЧЕСКИЕ НАУКИ |
S 98 Synthesis and structure of 2-ethoxy- and 2-aminomethylidene-3-fluoroalkyl-3-oxopropionates [Electronic resource] / M. V. Pryadeina, Ya. V. Burgart, V. I. Saloutin, P. A. Slepukhin, O. N. Chupakhin // Russian Journal of Organic Chemistry (Translation of Zhurnal Organicheskoi Khimii). - 2007. - Vol. 43, № 7. - P945-955 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: Condensation of ethyl 3-polyfluoroalkyl-3-oxopropionates with excess triethyl orthoformate gave ethyl 3-polyfluoroalkyl-2-ethoxymethylidene-3-oxopropionates which reacted with primary aliphatic, aromatic, and heterocyclic amines to form ethyl 2-alkyl(aryl, hetaryl)aminomethylidene-3-polyfluoroalkyl-3-oxopropionates. According to the X-ray diffraction and IR data, the latter exist in the crystalline state as the corresponding E isomers, while in solution (NMR data), as mixtures of Z and E isomers. Condensation of ethyl 2-ethoxymethylidene-3-oxopropionates with secondary heterocyclic amines (morpholine and pyrrolidine) led to the formation of 2-morpholino(pyrrolidin-1-yl)methylidene-3-fluoroalkyl-3-oxopropionates which were shown to exist as Z isomers both in the crystalline state and in solution \\\\Expert2\\nbo\\Russian Journal of Organic Chemistry\\2007, 43 (7), 945-955.pdf |