A 81 Aryne intermediates in the synthesis of polynuclear heterocyclic systems (Review) / I. S. Kovalev, D. S. Kopchuk, G. V. Zyryanov, P. A. Slepukhin, V. L. Rusinov, O. N. Chupakhin // Chemistry of Heterocyclic Compounds. - 2012. - Vol.48, №4. - С. 536-547 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): ARYNE INTERMEDIATES -- DIENOPHILES -- DIELS-ALDER REACTIONS Аннотация: Published examples of the polynuclear fused heterocyclic systems production by cycloaddition reactions involving aryne intermediates generated in situ are reviewed \\\\Expert2\\nbo\\Chemistry of Heterocyclic Compounds\\2012, v.48, N 4, p.536-547.pdf |
P 91 Preparation of (benzo)isoquinolines using in situ generated aryne intermediates [Electronic resource] / D. S. Kopchuk, G. V. Zyryanov, I. S. Kovalev, V. L. Rusinov, I. N. Egorov, O. N. Chupakhin // Chemistry of Heterocyclic Compounds. - 2013. - Vol.48, №12. - P1871-1873 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): (BENZO)ISOQUINOLINE -- 1,2,4-TRIAZINE -- ARYNE INTERMEDIATES -- CYCLOADDITION -- DIELS-ALDER REACTION \\\\expert2\\NBO\\Chemistry of Heterocyclic Compounds\\2013, v.48, N 12, p. 1871-1873.pdf |
P 91 Preparation of (benzo)isoquinilines using in situ generaled aryne intermediates / Д. С. Копчук, Г. В. Зырянов, И. С. Ковалев, И. Н. Егоров, В. Л. Русинов, О. Н. Чупахин // Химия гетероциклических соединений. - 2012. - № 12. - С. 1994-1997 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): СИНТЕЗ |
R 30 Reaction of 4,5-dimethoxy-1,2-dehydrobenzene with 3-(Pyridin-2-yl)-1,2,4-triazines [Electronic resource] / D. S. Kopchuk, I. L. Nikonov, G. V. Zyryanov, I. S. Kovalev, O. S. Taniya, V. L. Rusinov, O. N. Chupakhin // Russian Journal of Organic Chemistry (Translation of Zhurnal Organicheskoi Khimii). - 2015. - Vol. 85, № 8. - С. 1170-1173. - Bibliogr. : p. 1173 (30 ref.) Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): ISOQUINOLINE ALKALOIDS -- HETEROCYCLES -- ARYNE Аннотация: Reaction of 3-(pyridin-2-yl)-1,2,4-triazines with aryne intermediate, 4,5-dimethoxy-1,2-dehydrobenzene generated in situ, was investigated. As a result of the interaction products of the 1,2,4-triazine transformation are produced: 2,3-dimethoxy-10-(1H-1,2,3-triazol-1-yl)-pyrido[1,2-a]indoles, and also the products of Diels-Alder aza-reaction, 6,7-dimethoxy-1-(pyridin-2-yl)isoquinolines. \\\\expert2\\nbo\\Russian Journal of Organic Chemistry\\2015, 51, (8), 1170-1173.pdf |
A 81 Aryne approach towards 2,3-difluoro-10-(1H-1,2,3-triazol-1-yl)pyrido[1,2-a]indoles [Electronic resource] / D. S. Kopchuk, I. L. Nikonov, G. V. Zyryanov, E. V. Nosova, I. S. Kovalev, P. A. Slepukhin, V. L. Rusinov, O. N. Chupakhin // Mendeleev Communications. - 2015. - Vol. 25, № 1. - С. 13-14. - Bibliogr. : p. 14 (21 ref.) Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): HYDROGEN-BONDS -- FLUORINE -- N-OXIDES Аннотация: Reaction between 3-(2-pyridyl)-1,2,4-triazines and in situ generated 4,5-difluorobenzyne in toluene affords 2,3-difluoro-10-(1H-1,2,3-triazol-1-yl)pyrido[1,2-a]indoles. The structure of one representative compound was confirmed by X-ray diffraction analysis. \\\\expert2\\nbo\\Mendeleev Communications\\2015, v.25, p. 13-14.pdf |
A 81 Aryne approach towards 2,3-difluoro-10-(1H-1,2,3-triazol-1-yl)pyrido[1,2-a]indoles / D. S. Kopchuk, I. L. Nikonov, G. V. Zyryanov, E. V. Nosova, I. S. Kovalev, P. A. Slepukhin, V. L. Rusinov, O. N. Chupakhin // Mendeleev Communications. - 2015. - Vol. 25. - С. 13-14 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): 1H-1,2,3-TRIAZOL-1-YL -- INDOLES -- ARYNE \\\\expert2\\NBO\\Mendeleev Communications\\2015, v.25, p. 13-14.pdf |
Aryne-mediated transformations of 5-perfluorophenyl-substituted 3-(pyridin-2-yl)-1,2,4-triazines in the design of novel 10-(1h-1,2,3-triazol-1-yl)pyrido[1,2-a]indole fluorophores / T. D. Moseev, M. V. Varaksin, I. A. Lavrinchenko [и др.] // Tetrahedron. - 2020. - Vol. 76, № 18. - P131147 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): 1,2,3-TRIAZOLES -- ARYNE-MEDIATED TRANSFORMATIONS -- CAOSAMBHWGMFEW-UHFFFAOYSA-N -- CYFQLMLVDSTHGC-UHFFFAOYSA-N -- FLUOROARENES Аннотация: A number of novel fluorinated derivatives of the family of pyrido[1,2-a]indole fluorophores have first been synthesized via the aryne-mediated domino transformations of 5-(perfluorophenyl)-3-(pyridin-2-yl)-1,2,4-triazines. A comprehensive study of photophysical properties of the obtained polyfluoroaryl substituted derivatives, in which polyfluoroaryl, 1,2,3-triazole, and pyridoindole subunits contribute to a joint chromophore system, has shown that these compounds proved to exhibit a fluoresce with green light in acetonitrile solutions. |
Aryne-mediated transformations of 5-perfluorophenyl-substituted 3-(pyridin-2-yl)-1,2,4-triazines / T. D. Moseev, M. V. Varaksin, E. A. Nikiforov [et al.] // Actual problems of organic chemistry and biotechnology. - Екатеринбург, 2020. - P274-276 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): PYRIDO[1,2-A]INDOLES -- ARYNE -- REARRANGEMENT |
Aryne-mediated transformations of 3-(α- or γ-r-2-pyridyl)-1,2,4-triazines: id diels-alder reaction vs domino transformation / Sravya G. A. F. Khasanov, A. P. Krinochkin [et al.] // Polycyclic aromatic compounds. - 2021. - Vol. 42, № 8. - P4937-4947 Кл.слова (ненормированные): 3-(α- OR γ-R-PYRIDIN-2-YL)-1,2,4-TRIAIZINES -- INFLUENCE OF SUBSTITUENT -- ARYNES Аннотация: Interaction of 3-(α- or γ-R-pyridin-2-yl)-1,2,4-triazines (R = Me, CO2Me) with arynes affords either the domino-transformation products, pyrido[1,2-a]indoles, or Diels-Alder reaction ones, isoquinolines. The influence of the nature and/or position of the substituent on the reaction pathway is discussed. doi.org/10.1080/10406638.2021.1962371 |