A 81 Aryne intermediates in the synthesis of polynuclear heterocyclic systems (Review) / I. S. Kovalev, D. S. Kopchuk, G. V. Zyryanov, P. A. Slepukhin, V. L. Rusinov, O. N. Chupakhin // Chemistry of Heterocyclic Compounds. - 2012. - Vol.48, №4. - С. 536-547 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): ARYNE INTERMEDIATES -- DIENOPHILES -- DIELS-ALDER REACTIONS Аннотация: Published examples of the polynuclear fused heterocyclic systems production by cycloaddition reactions involving aryne intermediates generated in situ are reviewed \\\\Expert2\\nbo\\Chemistry of Heterocyclic Compounds\\2012, v.48, N 4, p.536-547.pdf |
2-Aminooxazoles as novel dienophiles in the inverse demand Diels–Alder reaction with 1,2,4-triazines / A. P. Krinochkin, G. Mallikarjuna Reddy, D. S. Kopchuk [et al.] // Mendeleev Communications. - 2021. - Vol. 31, № 4. - P542-544 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): 1,2,4-TRIAZINES -- OXAZOL-2-AMINES -- DIELS–ALDER REACTION -- 2,2'-BIPYRIDIN-3-OLS Аннотация: High temperature coupling of 6-aryl-5-cyano-3-(pyridin-2-yl)-1,2,4-triazines with 2-amino-4-aryloxazoles proceeds as the inverse demand Diels–Alder reaction between the oxazole moiety as dienophile and the 1,2,4-triazine moiety as diene to construct new 4,5-diaryl-6-cyano-3-hydroxypyridin-2-yl fragment. A reaction mechanism is proposed, and the structure of the key-product is proved by the X-ray diffraction analysis. |