T 44 The elaboration of New Elementorganic Hydrogels for Pharmaceutical Compositions of Local and External Application: the 3rd China-Russia international symposium on pharmacology [Text] : доклад, тезисы доклада / L. P. Larionov, T. G. Khonina, P. V. Sorokin, E. V. Shadrina, A. A. Boyko, N. A. Zabokritskii, G. B. Philippova, O. N. Chupakhin // Pharmacology. - Harbin : Harbin medical university, 2008. - P4-5 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): HYDROGELS -- GLYCEROLATES |
T 44 The Design and investigation of Ca, P, Si-Containing Hydrogels for pharmaceutical compositions for local and external application [Text] : доклад, тезисы доклада / E. A. Bogdanova, N. A. Sabirzyanov, T. G. Khonina, L. P. Larionov, N. G. Sarkisyan, G. I. Ron // Pharmacology: the 3rd China-Russia International symposium on pharmacology. - Harbin : Harbin medical university, 2008. - P18-19 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): HYDROGELS |
S 98 Synthesis of hydrogels based on silicon polyolates [Electronic resource] / T. G. Khonina, E. V. Shadrina, A. A. Boyko, O. N. Chupakhin, L. P. Larionov, A. A. Volkov, V. D. Burda // Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya). - 2010. - Vol. 59, № 1. - P75-80 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): ORGANOSILICON COMPOUNDS -- DIOLS -- GLYCEROL Аннотация: Biologically active hydrogels based on silicon polyolates, which are the products of reactions of tetraethoxy- and methyltriethoxysilanes with polyols (1,2-propanediol, glycerol, polyethylene glycol), were synthesized. The optimal conditions for hydrogel formation and hydrogel composition were determined. The acute toxicity and transcutaneous and wound-healing activities of the synthesized compounds were studied. The experimental results show that hydrogels based on silicon polyolates can be recommended for further preclinical and clinical tests with the purpose of their use in medical practice both as self-sufficient agents and ointment bases of pharmaceutical compositions with wound-healing, regenerative, and transcutaneous action \\\\Expert2\\nbo\\Russian Chemical Bulletin\\2010, 59 (1), 75-80.pdf |
С 38 Синтез, токсичность и трансдермальная проницаемость глицератов кремния и гидрогелей на их основе [] = Synthesis, toxicity, and percutaneous activity of silicon glycerolates and related hydrogels / Т. Г. Хонина, О. Н. Чупахин, Л. П. Ларионов, Т. Г. Бояковская, А. Л. Суворов, Е. В. Шадрина // Химико-фармацевтический журнал. - 2008. - № 11. - С. 5-9 : рис., табл., граф. - Библиогр.: с. 9 (12 назв.) . - ISSN 0023-1134 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): КРЕМНИЙ -- ГЛИЦЕРАТЫ КРЕМНИЯ -- ГИДРОГЕЛИ -- ГЕЛЕОБРАЗОВАНИЕ -- ПРОВОДНИКИ ТРАНСКУТАННЫЕ -- СИНТЕЗ -- ТОКСИЧНОСТЬ -- ПРОНИЦАЕМОСТЬ ТРАНСДЕРМАЛЬНАЯ |
S 85 Stnthesis, toxicity, and percutaneous activity of silicon glycerolates and related hydrogels [Electronic resource] / T. G. Khonina, O. N. Chupakhin, L. P. Larionov, T. G. Boyakovskaya, A. L. Suvorov, E. V. Shadrina // Pharmaceutical Chemistry Journal. - 2008. - Vol. 42, № 11. - P609-613 : il. - Bibliogr. : p. 612 (12 ref.) Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): SILICON -- SILICON GLYCEROLATES -- HYDROGELS -- SYNTHESIS -- TOXICITY -- PERCUTANEOUS ACTIVITY \\\\Expert2\\nbo\\Pharmaceutical Chemistry Journal\\2008, 42 (11), 609.pdf |
O-72 Organosilicontitanium glycerohydrogels are the new base of topical phermaceutical composition [Text] : доклад, тезисы доклада / T. G. Khonina, L. P. Larionov, T. G. Boyakovskaya, E. V. Shadrina, A. L. Suvorov // Fundamental pharmacology and pharmacy-clinical practice, Perm, 25-27 September 2006 : materials of 2-nd Russian-Chinese International scientific conference of pharnacology. - Perm, 2006. - P171-172 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): HYDROGELS -- GLYCEROHYDROGELS -- PHARMACEUTICAL COMPOSITION -- OINTMENTS -- MEDICAMENTS |
B 83 Boyakovskaya, T. G. Siliconorganic glicerohydrogels as a new base for creation of medical and curative-cosmetic ointments [Text] : доклад, тезисы доклада / T. G. Boyakovskaya, L. P. Larionov, T. G. Honina // International conference of pharmacology, Harbin, 1-4 July 2005. - Harbin, 2005. - P50-51 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): HYDROGELS -- GLICEROHYDROGELS -- SILICONORGANIC GLICEROHYDROGELS -- OINTMENTS -- MEDICAL OINTMENTS -- CURATIVE-COSMETIC OINTMENTS |
К 29 Каталитическая активность смешанных гидрогелей диоксидов титана и кремния в реакциях жидкофазного окислительного дегидрирования [] = Catalytic activity of mixed titanium-silica dioxide hydrogels in reactions of oxiding liquid-phase dehydrogenation / В. Г. Харчук, М. Ю. Янченко, Л. Ю. Булдакова, О. В. Корякова, Л. А. Петров // VII Рос. конф. "Механизмы каталитических реакций" : тез. докл. - Новосибирск, 2006. - С. 144 Рубрики: ХИМИЧЕСКИЕ НАУКИ |
M 45 Mechanism of structural networking in hydrogels based on silicon and titanium glycerolates / T. G. Khonina, A. P. Safronov, E. V. Shadrina, M. V. Ivanenko, A. I. Suvorova, O. N. Chupakhin // Journal of Colloid and Intrface Science. - 2012. - Vol. 365, № 1. - С. 81-89 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): HOFMEISTER SERIES -- TITANIUM–GLYCEROL HYDROGELS -- SCHULTZE–HARDY RULE Аннотация: Formation of organic/inorganic hydrogels based on silicon– and titanium–glycerol precursors synthesized by transesterification of alkoxy derivatives in excess of glycerol was investigated. The precursors in excess of glycerol and obtained gels were studied by chemical and physical methods including gelation kinetics, IR spectroscopy, XRD, dynamic and electrophoretic light scattering, mechanical deformation, which disclosed the basic difference in the gelation mechanism and structure of network in the hydrogels. Due to this difference, the gelation time of silicon– and titanium–glycerol precursors depended on pH or electrolyte addition in an opposite way. In the wide pH range, silicon–glycerol hydrogel was a polymeric single-phase system formed by the polymeric network homogeneously swollen in liquid water/glycerol medium. Flory–Rehner theory applied to the elastic modulus of these gels gave 40–180 monomer base units in the subchains of the network depending on water content in the gel. The mechanism of networking was three-dimensional polycondensation promoted by the electrically charged functional groups attached to the flexible polymeric chains. Electrolyte solutions provided the gelation according to Hofmeister series. Titanium–glycerol hydrogels were heterogeneous colloid systems at pH > 1.5 and single-phase polymeric gels at lower pH. Electrolyte solutions provided the gelation according to Schultze–Hardy rule \\\\Expert2\\nbo\\Journal of Colloid and Interface Science\\2012, v.365, p.81.pdf |
S 98 Synthesis of pharmacologically active hydrogels [Electronic resource] / M. V. Ivanenko, T. G. Khonina, O. N. Chupakhin, L. P. Larionov // Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya). - 2012. - Vol.61, №11. - С. 2163-2171. - Bibliogr. : p. 2171 (30 ref.) Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): SILICON POLYOLATES -- TITANIUM POLYOLATES -- WOUND-HEALING Аннотация: The target synthesis of new biologically active hydrogels based on combined silicon and titanium polyolates was carried out. The optimum conditions for hydrogel formation and their composition were determined. The type of hydrogels and mechanisms of gelation depend on the nature of polyols: gels based on combined silicon and titanium polyethylene glycolates are polymeric and formed via the polycondensation mechanism, whereas gels based on combined silicon and titanium glycerolates are colloidal and formed via the coagulation—condensation mechanism. The combined hydrogels based on silicon dimethyl glycerolates and titanium tetraglycerolate exhibit enhanced transcutaneous, wound healing, and regenerating activity \\\\expert2\\NBO\\Russian Chemical Bulletin\\2012, 61 (11), 2163-2171.pdf |
I-70 Investigation of regularities, mechanism of formation, and structure of hydrogels based on silicon - and titanium polyolates / T. G. Khonina, M. V. Ivanenko, E. V. Shadrina, O. N. Chupakhin // Третья международная конф. стран СНГ "Золь-гель синтез и исследование неорганических соединений, гибридных функциональных материалов и гибридных систем" "Золь-гель 2014", Суздаль, 8-12 сентября 2014 г. : докл. - Суздаль, 2014. - С. 24. - Bibliogr. : p. 24 (2 ref.) Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): HYDROGELS -- TITANIUM POLYOLATES |
S 53 Shadrina, E. V. Gel formation and structure of hybrid chitosan-silicone-containing hydrogels / E. V. Shadrina, T. G. Khonina // Третья международная конф. стран СНГ "Золь-гель синтез и исследование неорганических соединений, гибридных функциональных материалов и гибридных систем" "Золь-гель 2014", Суздаль, 8-12 сентября 2014 г. : докл. - Суздаль, 2014. - С. 168. - Bibliogr. : p. 168 (3 ref.) Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): GELS -- CHITOSAN -- SILICONE |
I-98 Ivanenko, M. V. Polymeric and colloidal hydrogels based on titanium polyolates / M. V. Ivanenko, T. G. Khonina // Третья международная конф. стран СНГ "Золь-гель синтез и исследование неорганических соединений, гибридных функциональных материалов и гибридных систем" "Золь-гель 2014", Суздаль, 8-12 сентября 2014 г. : докл. - Суздаль, 2014. - С. 169-170. - Bibliogr. : p. 170 (6 ref.) Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): GLYCOLATE -- TITANIUM(IV) -- SOL—GEL PROCESS |
T 44 The structural features of zinc-silicone-containing glycerohydrogels / A. N. Bondarev, I. N. Shtanko, E. A. Bogdanova, A. E. Lebedev, D. D. Lovskaya, T. G. Khonina // Третья международная конф. стран СНГ "Золь-гель синтез и исследование неорганических соединений, гибридных функциональных материалов и гибридных систем" "Золь-гель 2014", Суздаль, 8-12 сентября 2014 г. : докл. - Суздаль, 2014. - С. 171. - Bibliogr. : p. 171 (4 ref.) Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): AEROGEL -- HYDROGELS -- ZINC |
I-70 Investigation of Regularities, Mechanism of Formation, and Structure of Hydrogels based on Silicon and Titanium Polyolates / T. G. Khonina, M. V. Ivanenko, E. V. Shadrina, O. N. Chupakhin // Третья международная конференция стран СНГ «Золь-гель 2014», Суздаль, 8–12 сентября 2014 г. : тез. докл. - Суздаль, 2014. - С. 24 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): HYDROGELS -- TITANIUM POLYOLATES -- SILICON POLYOLATES |
I-98 Ivanenko, M. V. Polymeric and Colloidal Hydrogels based on Titanium Polyolates / M. V. Ivanenko, T. G. Khonina // IV международная конф. "Техническая химия. От теории к практике", Пермь, 20-24 октября 2014 г. : тез. докл. - Пермь, 2014. - С. 169-170 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): COLLOIDAl HYDROGELS -- POLYMERIC HYDROGELS -- TITANIUM POLYOLATES |
L 31 Larchenko, E. Yu. Gel Formation and Structure of hybrid Chitosan–Silicone-containing Hydrogels / E. Yu. Larchenko, E. V. Shadrina, T. G. Khonina // IV международная конф. "Техническая химия. От теории к практике", Пермь, 20-24 октября 2014 г. : тез. докл. - Пермь, 2014. - С. 168 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): HYDROGELS -- CHITOSAN-SILICONE-CONTAINING |
F 33 Features of silicon- and titanium-polyethylene glycol precursors in sol-gel synthesis of new hydrogels [Electronic resource] / T. G. Khonina, A. P. Safronov, M. V. Ivanenko, E. V. Shadrina, O. N. Chupakhin // Journal of Materials Chemistry B. - 2015. - Vol. 3, № 27. - С. 5490-5500. - Bibliogr. : p. 5499-5500 (38 ref.) Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): MODIFIED SILANES -- MINERALIZATION -- MONOLITHS Аннотация: The formation of organic/inorganic hydrogels based on silicon and titanium polyethylene glycolates, new biocompatible water-soluble precursors in sol-gel processing, was investigated. The influence of different factors on the gelation process, such as excess of PEG, water molar content, pH of medium, electrolyte additives, was investigated in comparison with silicon-and titanium-glycerol precursors. The specific features of gelation for each type of precursor were revealed. It has been determined that titanium polyethylene glycolates synthesized and used in the excess of PEG formed transparent polymeric hydrogels resistant to syneresis under certain conditions. The titanium polyethylene glycolates synthesized without excess of PEG formed turbid heterogeneous colloidal gels. In the case of silicon polyethylene glycolates the hydrogels obtained were polymeric. Dynamic light scattering was used to confirm the polymeric or colloidal type of gelation. The solid and liquid phases of polymeric silicon- and titanium-polyethylene glycol hydrogels were separated by exhaustive extraction. The solid phase was characterized by combined thermal analysis with simultaneous quadruple mass spectrometry, XRD, IR spectroscopy, and liquid phase-atomic emission spectroscopy. The structural features of polymeric gels were investigated by SEM and TEM methods. The cross-linking density of polymeric hydrogels was evaluated using Flory-Rehner theory based on the mechanical properties of swollen networks of flexible polymeric chains \\\\expert2\\nbo\\Journal of Materials Chemistry B\\2015. V. 3, N 27. P. 5490-5500.pdf |
N 89 Novoselova, M. E. Formation regularities of silicon-polysaccaride-containing polyolate hydrogels / M. E. Novoselova, M. V. Ivanenko, E. Yu. Nikitina, T. G. Khonina // Современные синтетические методологии для создания лекарственных препаратов и функциональных материалов (MOSM2018): вторая международная научно-практическая конференция : материалы и доклады. - Екатеринбург, 2019. - С. 120 Рубрики: ХИМИЧЕСКИЕ НАУКИ |
Carboxyalkylchitosan-based hydrogels with “imine clip”: enhanced stability and amino acids-induced disassembly under physiological conditions / S. Bratskaya, Y. Privar, A. Skatova [et al.] // Carbohydrate polymers. - 2021. - Vol. 274. - P118618 Рубрики: ХИМИЧЕСКИЕ НАУКИ |