T 82 Transformations of 1,2,4-triazine 4-oxides to pyridazines and triazolo[4,3-b]pyridazines by the action of substituted acetonitriles [Electronic resource] / D. N. Kozhevnikov, N. N. Kataeva, V. L. Rusinov, O. N. Chupakhin, G. G. Aleksandrov> // Mendeleev Communications. - 2005. - Vol. 15, № 1. - P31-33 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: Two types of ring transformations of 1,2,4-triazine to pyridazine were found: 1,2,4-triazine 4-oxides bearing ortho-halophenyl in the 3-position react with phenylacetonitrile under basic conditions to form 3-(2-oxyphenyl)[1,2,4]triazolo[4,3-b]pyridazines, while the reactions of 3,6-diaryl-1,2,4-triazin 4-oxides with sodium ethyl cyanoacetate afforded 2-aminopyridazines. \\\\Expert2\\nbo\\Mendeleev Communications\\2005, v.15, p.31.pdf |
U 52 Unexpected formation of pyridazine-5,6-dione derivatives in the reactions of 3-arylhydrazono-2,4-dioxo-4-pentafluorophenylbutanoates with hydrazines [Electronic resource] / A. S. Fokin, Ya. V. Burgart, V. I. Saloutin, O. N. Chupakhin> // Mendeleev Communications. - 2005. - Vol. 15, № 6. - P252-253 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): PYRIDAZINES Аннотация: The reactions of 3-arylhydrazono-2,4-dioxo-4-pentafluorophenylbutanoates with hydrazine hydrate and phenylhydrazine resulted in the formation of 4-arylazo-3-pentafluorophenyl-1,2-dihydro-5H,6H-pyridazine-5,6-diones or 6-aryl-2-phenyl-7,8,9,10-tetrafluoro-2,3,4,6-tetrahydropyridazino[4,3-c]cinnoline-3,4-dione. \\\\Expert2\\nbo\\Mendeleev Communications\\2005, v.15, p.252.pdf |
Z 99 [3+2]- Versus [4+2]-cycloaddition reactions of 3-methylsulfanyl-2-arylazo-3-(pyrrolidin-1-yl)acrylonitriles with N-substituted maleimides involving pyrrolidine-derived azomethine ylides [Text] / T. G. Deryabina, N. P. Belskaia, M. I. Kodess, V. A. Bakulev> // Tetrahedron Letters. - 2006. - Vol. 47, № 11. - P1853-1855 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: 3-Methylsulfanyl-2-arylazo-3-(pyrrolidin-1-yl)acrylonitriles do not enter into [4+2]-cycloaddition reactions with maleimides to form the expected pyrrolo-pyridazines. Instead the formation of novel pyrrolo-pyridazines of type 4 takes place via a formal [3+2]-cycloaddition of initially formed pyrrolidine-derived azomethine ylides 7. The mechanism leading to the final product is discussed???? \\\\Expert2\\nbo\\Tetrahedron Letters\\2006, v. 47, p.1853.pdf |
T 82 Transformations of C-adducts of 1,4-diazinium salts with dicarbonyl compounds into polycyclic systems [Electronic resource] / E. V. Verbitskiy, P. A. Slepukhin, G. L. Rusinov, V. N. Charushin> // Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya). - 2008. - Vol. 57, № 3. - P652-656 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: C-Adducts of 5-(het)aryl-2,3-dicyano-1-pyrazinium salts containing a residue of a 1,3-dicarbonyl compound at position 6 can be involved in the cyclization with hydrazine hydrate giving rise to pyrazino[2,3-c]pyridazines along with the expected pyrazole derivatives. The reactions of the same ?H-adducts with hydroxylamine unexpectedly afforded triazacyclopenta[a]indene derivatives. The crystallographic data on the three-dimensional structures of new polycyclic compounds were obtained \\\\Expert2\\nbo\\Russian Chemical Bulletin\\2008, 57 (3), 652.pdf |
Z 99 [4+2]-Cycloaddition of 3,6-bis(3,5-dimethyl-4-R-pyrazol-1-yl)-1,2,4,5-tetrazines with alkenes [Electronic resource] / G. L. Rusinov, R. I. Ishmetova, N. I. Latosh, I. N. Ganebnuikh, O. N. Chupakhin, V. A. Potemkin> // Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya). - 2000. - Vol. 49, № 2. - P355-362 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: A number of 1,4-dihydropyridazines and pyridazines were prepared by the Diels-Alder reaction with an inverse electron demand from cyclic heterodiene systems, 3,6-bis(3,5-dimethyl-4-R-pyrazol-1-yl)-1,2,4,5-tetrazines, and some enamines as well as from 4-vinylpyridine, butyl vinyl ether, phenylacetylene, and acrylamide. The reaction of 3,6-bis(3,5-dimethylpyrazol-1-yl)-1,2,4,5-tetrazine with styrene afforded 4,5-dihydropyridazine, which was readily oxidized by atmospheric oxygen to form the corresponding pyridazine. Electron-withdrawing substituents (Br or Cl) in the pyrazole rings accelerate [4+2]-cycloaddition. When heated, 1,4-dihydropyridazines, which were synthesized from tetrazines and enamines, eliminated amine to give pyridazines. The reactivities of tetrazines were evaluated by quantum-chemical methods. \\\\Expert2\\nbo\\Russian Chemical Bulletin\\2000, 49 (2), 355.pdf |
Z 99 [4+2] Cycloaddition reactions of 1,2,4,5-tetrazines with allylcarboranes [Electronic resource] / G. L. Rusinov, R. I. Ishmetova, S. G. Tolshchina, N. K. Ignatenko, I. N. Ganebnuikh, P. A. Slepukhin, V. A. Ol'shevskaya, V. N. Kalinin, V. N. Charushin> // Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya). - 2010. - Vol. 59, № 1. - P116-121 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): ALLYLCARBORANES -- PYRIDAZINES -- [4+2] CYCLOADDITION???? Аннотация: The [4+2] cycloaddition reactions of 3,6-disubstituted 1,2,4,5-tetrazines with 9-allyl-1,7-,9-allyl-1,2-dicarba-closo-dodecaboranes and 1-allyl-2-isopropyl-1,2-dicarba-closo-dodecab-orane have been studied. The pyridazines containing carborane cage have been synthesized for the first time \\\\Expert2\\nbo\\Russian Chemical Bulletin\\2009, 59 (1), 116-121.pdf |
R 30 Reactions of 3,6-bis(3,5-dimethyl-4-r-pyrazol-1-yl)-1,2,4,5-tetrazines with indole and 1,3,3-trimethyl-2-methyleneindoline [Text] / R. I. Ishmetova, N. K. Ignatenko, I. N. Ganebnuikh, S. G. Tolshchina, P. A. Slepukhin, G. L. Rusinov> // Heterocycles. - 2011. - Vol. 83, № 6. - P1363-1370 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: It has been found that 3,6-bis(3,5-dimethyl-4-R-pyrazol-1-yl)-1,2,4,5-tetrazines react with indole and 1,3,3-trimethyl-2-methyleneindoline to give pyridazines as [4+2]cycloaddition products. 1,3,3-Trimethyl-2-methyleneindoline has been shown to act as C-nucleophile in the substitution of pyrazolyl group as well as in the reactions of tetrazine ring expansion in [1,2,4]triazolo[4,3-b][1,2,4,5]tetrazine derivatives |
S 90 Study of the supramolecular structures of complexes of carborane-containing pyridazines with 2,3,5,6-tetrachloro-1,4-dihydroxybenzene [Electronic resource] / P. A. Slepukhin, S. G. Tolshchina, A. V. Ignatenko, E. F. Zhilina, V. N. Charushin> // Crystallography Reports. - 2014. - Vol.59, №2. - С. 202-206. - Bibliogr. : p. 206 (9 ref.) Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): PYRIDAZINES -- HETEROCYCLIC SUBSTITUENTS -- CARBORANE MOIETY Аннотация: The structures and characteristic features of the molecular packing patterns of complexes of pyridazines containing heterocyclic substituents and the carborane moiety with 2,3,5,6-tetrachlorohydroquinone (TCHQ) were investigated. It was shown that TCHQ can form supramolecular assemblies with carborane-containing substituted pyridazines. The stoichiometry and three-dimensional structures of these assemblies depend on the substituents in the pyridazine ring and are formed via O-H⋯N hydrogen bonding between TCHQ and heterocyclic molecules \\\\expert2\\NBO\\Crystallography Reports (Кристаллография)\\2014, v.59, N 2, p.202-206.pdf |
S 90 Study of the supramolecular structures of complexes of carborane-containing pyridazines with 2,3,5,6-tetrachloro-1,4-dihydroxybenzene [Electronic resource] / P. A. Slepukhin, S. G. Tolshchina, N. K. Ignatenko, R. I. Ishmetova, G. L. Rusinov, E. F. Zhilina, V. N. Charushin> // Crystallography Reports. - 2014. - Vol. 59, № 2. - С. 202-206. - Bibliogr. : p. 206 (9 ref.) Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): MOLECULAR PACKING PATTERNS -- PYRIDAZINES CONTAINING HETEROCYCLIC SUBSTITUENTS -- TETRACHLOROHYDROQUINONE Аннотация: The structures and characteristic features of the molecular packing patterns of complexes of pyridazines containing heterocyclic substituents and the carborane moiety with 2,3,5,6-tetrachlorohydroquinone (TCHQ) were investigated. It was shown that TCHQ can form supramolecular assemblies with carborane-containing substituted pyridazines. The stoichiometry and three-dimensional structures of these assemblies depend on the substituents in the pyridazine ring and are formed via O-H…N hydrogen bonding between TCHQ and heterocyclic molecules \\\\expert2\\nbo\\Crystallography Reports (Кристаллография)\\2014, v.59, N 2, p.202-206.pdf |
A 10 A novel transformation of b-1,2,3-thiadiazol-5-yl enamines into thieno[2,3-d]pyridazines / Yu. Rozin, S. Zhidovinov, T. Beryozkina, Yu. Shafran, G. Lubec, O. S. Eltsov, P. A. Slepukhin, W. Dehaen, V. A. Bakulev> // Tetrahedron Letters. - 2015. - Vol. 56. - С. 1545-1547 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): B-1,2,3-THIADIAZOL-5-YL ENAMINES -- ENAMINES -- PYRIDAZINES \\\\expert2\\NBO\\Tetrahedron Letters\\2015, v. 56, p. 1545.pdf |
S 98 Synthesis of 4-arylamino-3-(trifluoromethyl)pyridazines and pyridazino[3,4-b]quinoxalines (as by-products) from 3-aroylmethyl-2-(trifluoromethyl)quinoxalines and hydrazine hydrate / V. Ya. Sosnovskikh, A. V. Safrygin, R. A. Irgashev, M. A. Ezhikova, M. I. Kodess> // RSC Advances. - 2016. - Vol. 6. - С. 30056-30069. - Bibliogr. : p. 30069 (14 ref.) Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): SYNTHESIS -- HYDRAZINE HYDRATE -- 4-ARYLAMINO-3-(TRIFLUOROMETHYL)PYRIDAZINES \\\\expert2\\nbo\\RSC Advances\\2016. Vol. 6, С. 30056.pdf |