R 30 Reaction of 2-polyfluoroacylcyclohexanones with semicarbazides [Electronic resource] / K. I. Pashkevich, D. V. Sevenard, O. G. Khomutov, O. V. Shishkin, E. V. Solomovich> // Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya). - 1999. - Vol. 48, N 2. - P359-363 Рубрики: ХИМИЧЕСКИЕ НАУКИ \\\\Expert2\\nbo\\Russian Chemical Bulletin\\1999, 48 (2), 359-363.pdf |
P 80 Polyfunctional fluoroalkyl-containing carbonyl compounds in the synthesis of heterocycles [Electronic resource] / K. I. Pashkevich, V. I. Filyakova, V. G. Ratner, O. G. Khomutov> // Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya). - 1998. - Vol. 47, N 7. - P1239-1247 Рубрики: ХИМИЧЕСКИЕ НАУКИ \\\\Expert2\\nbo\\Russian Chemical Bulletin\\1998, 47 (7), 1239-1247.pdf |
S 98 Synthesis of fluoroalkyl-containing beta-hydroxyketones by reduction of the corresponding beta-diketone derivatives [Electronic resource] / K. I. Pashkevich, V. G. Ratner, O. G. Khomutov, V. B. Korolev, V. I. Filyakova> // Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya). - 1996. - Vol. 45, N 6. - P1423-1424 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: The regioselective synthesis of fluoroalkyl-containing beta-hydroxyketones by the reduction of the salts of the corresponding beta-diketones with LiAlH4 was proposed. This is the sole method for the synthsis of beta-hydroxyketones with two fluoroalkyl substituents \\\\Expert2\\nbo\\Russian Chemical Bulletin\\1996, 45 (6), 1423-1424.pdf |
S 98 Synthesis of polyfluorinated ketones via the ATE-complexes [Electronic resource] / K. I. Pashkevich, O. G. Khomutov, V. I. Filyakova, A. V. Kuchin> // Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya). - 1994. - Vol. 43, N 6. - P1002-1003 Рубрики: ХИМИЧЕСКИЕ НАУКИ \\\\Expert2\\nbo\\Russian Chemical Bulletin\\1994, 43 (6), 1002-1003.pdf |
K 42 Khomutov, O. G. Synthesis of 3-fluoroalkyl-2-aziridinyl ketones [Electronic resource] / O. G. Khomutov, V. I. Filyakova, K. I. Pashkevich> // Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya). - 1994. - Vol. 43, N 2. - P261-263 Рубрики: ХИМИЧЕСКИЕ НАУКИ \\\\Expert2\\nbo\\Russian Chemical Bulletin\\1994, 43 (2), 261-263.pdf |
A 53 An effective synthesis method for secondary fluorinated alcohols via the reaction of esters of polyfluorinated acids with trialkylalanes [Electronic resource] / O. G. Khomutov, V. I. Filyakova, A. V. Kuchin, K. I. Pashkevich, G. A. Tolstikov> // Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya). - 1992. - Vol. 41, N 10. - P1834-1835 Рубрики: ХИМИЧЕСКИЕ НАУКИ \\\\Expert2\\nbo\\Russian Chemical Bulletin\\1992, 41 (10), 1834.pdf |
P 80 Polyfunctional Fluoroalkyl Carbonyl Compounds as Building Blocks for Synthesis of Heterocycles [Text] : доклад, тезисы доклада / K. I. Pashkevich, V. I. Filyakova, V. G. Ratner, O. G. Khomutov, O. A. Kuznetsova, D. V. Sevenard> // International Memorial I.Postovsky Conference on Organic Chemisty, Ekaterinburg, March 17-20, 1998 : program and abstracts. - Ekaterinburg, 1998. - P107 Рубрики: ХИМИЧЕСКИЕ НАУКИ |
S 51 Sevenard, D. V. Interaction of 2-polyfluoroalkyl Cyclalkanones with Hydroxylamine and Hydrazines [Text] : доклад, тезисы доклада / D. V. Sevenard, O. G. Khomutov, K. I. Pashkevich> // International Memorial I.Postovsky Conference on Organic Chemisty, Ekaterinburg, March 17-20, 1998 : program and abstracts. - Ekaterinburg, 1998. - P119 Рубрики: ХИМИЧЕСКИЕ НАУКИ |
A 30 Alanines in Synthesis of Fluorinated Functional Compounds [Text] / A. V. Kuchin, O. G. Khomutov, V. I. Filyakova, K. I. Pashkevich> // Journal of Fluorine Chemistry. - 1991. - Vol. 54, N 1/3. - P220 Рубрики: ХИМИЧЕСКИЕ НАУКИ |
S 98 Synthesis of trifluoroalkyl- and fluoroaryl-substituted 4,5-dihydro-1H-1,2,4-triazole-5-thiones [Electronic resource] / E. B. Vasil'eva, D. V. Sevenard, O. G. Khomutov, O. A. Kuznetsova, N. S. Karpenko, V. I. Filyakova> // Russian Journal of Organic Chemistry (Translation of Zhurnal Organicheskoi Khimii). - 2004. - Vol. 40, № 6. - P874-878. - Библиогр. : с. 878 (8 назв.) Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: Reactions of 4-(4-fluorophenyl)-, 4-(4-trifluoromethoxyphenyl)-, 4-(3,4-difluorophenyl)-, 4-(4-trifluoromethylphenyl)-, 4-piperidino-, and 4-(3-pyridyl)thiosemicarbazides with esters gave the corresponding 3,4-disubstituted 4,5-dihydro-1H-1,2,4-triazole-5-thiones and their S-alkyl derivatives. Analogous reactions with methyl 2,2,3,3,4,4,5,5-octafluoropentanoate and 2,2,3,3,4,4,5,5-octafluoropentanenitrile afforded, respectively, the acylation and addition products. \\\\Expert2\\nbo\\Russian Journal of Organic Chemistry\\2004, 40 (6), 874.pdf |
S 98 Syntheses of novel 4-polyfluoroalkyl-substituted 5,6-oligomethylene pyrimidines [Text] / D. V. Sevenard, O. G. Khomutov, O. V. Koryakova, V. V. Sattarova, M. I. Kodess, J. Stelten, I. Loop, E. Lork, K. I. Pashkevich, G. -V. Roeschenthaler> // Synthesis. - 2000. - № 12. - P1738-1748 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: 2-Acylcycloalkanones having polyfluoroalkyl groups react with guanidine, urea, thiourea, methylisothiourea, benzamidine, guanylthiourea, dicyanodiamide, and trifluoroacetylurea by Lewis-acid catalysis to form the corresponding 5,6-oligomethylene pyrimidines. A decrease in the yields along with increase of polyflyoroalkyl substituent length in the molecule of the starting 1,3-diketone was observed in the case of reagents with lower nucleophilicity (urea, thiourea, dicyanodiamide). The pyrimidines obtained from aromatic aldehydes showed E-configuration with respect to the arylidene double bond. Tautomeric structures as a function of the substituent in 2 position in the pyrimidine ring both in liquid and solid state were investigated by X-ray diffraction, IR and NMR spectroscopy. \\\\expert2\\nbo\\Synthesis\\2000, № 12. p.1738.pdf |
N 89 Novel polyfluoroalkylated pyrazoles from 2-polyfluoroacylcycloalkanones and hydrazines: Syntheses and unequivocal molecular structure assignment [Text] / D. V. Sevenard, O. G. Khomutov, M. I. Kodess, K. I. Pashkevich, I. Loop, E. Lork, G. -V. Roeschenthaler> // Canadian Journal of Chemistry. - 2001. - Vol. 79, № 2. - P183-194 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): HYDRAZINES -- MOLECULAR STRUCTURE -- ISOMERIC PYRAZOLES; Аннотация: The reaction between 2-trifluoroacetylcycloalkanones and methylhydrazine or phenylhydrazine exclusively yields 3-CF3-pyrazoles. When the chain length of the polyfluorinated substituent in RFC(O) group increases, 5-RF-pyrazoles are isolated. The reaction of 2-trifluoroacetylcyclohexanone with 2-hydrazinopyradine gives 5-hydroxypyrazoline, an intermediate in the formation of 5-CF3-pyrazoles. The regiochemistry of the condensation is probably controlled by the nucleophilicity of the terminal nitrogen in the mono substituted hydrazines and by the steric requirements of the RF group in the 1,3-diketones. Polymethylene chain containing pyrazoles obtained from the 1,3-diketones in question and hydrazine prefer the 3-RF tautomeric form, irrespective of carbocyclic ring size and polyfluoroalkyl group chain length. |
C 73 Condensation of 2-polyfluoroacycloalkanones with aldehydes and dimethylformamide-dimethylacetal [Text] / D. V. Sevenard, O. G. Khomutov, M. I. Kodess, K. I. Pashkevich, I. Loop, E. Lork, G. -V. Roeschenthaler> // Australian Journal of Chemistry. - 2001. - Vol. 54, № 3. - P157-163 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: Polyfluorinated 1,3-diketones containing carbocycles react with aldehydes under Lewis-acid catalysis and also with dimethylformamide-dimetylacetal without catalysis, yielding exclusively (E)-configured condensation products involving the methylene group of the carbocycle. Novel trifluoromethylated chromenes are prepared from 2-trifluoroacetylcycloalkanones and salicylaldehyde. The structures of two new compounds, 2-(E)-benzylidene-6-trifluoroacetylcyclohexanone and 4-trifluoroacetyl-2,3-dihydro-1H-xantene, are confirmed by X-ray structure analysis. |
M 61 Metal and boron derivatives of fluorinated cyclic 1,3-dicarbonyl compounds [Text] / D. V. Sevenard, O. G. Khomutov, N. S. Boltacheva, V. I. Filyakova, V. Vogel, V. Ya. Sosnovskikh, V. O. Iaroshenko, G. -V. Roeschenthaler> // Zeitschrift fur Naturforschung - Section B. Journal of Chemical Science. - 2009. - Vol. 64, № 5. - P541-550 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: Starting from the corresponding cyclic 1,3-diketones or other precursors (cyclic ketones as well as lactones), several new salts and chelate complexes of fluorinated 1,3-dicarbonyls were obtained. Their preparative significance was demonstrated by straightforward syntheses of fluorinated pyrazoles, benzimidazoles and 1,7-ketoesters. The structure of a boron chelate of 2-(trifluoroacetyl)- cyclohexanone was investigated by X-ray diffraction |
K 42 Khomutov, O. G. Synthesis ofN-alkylamides of 3-fluoroalkylaziridine-2-carboxylic ac [Electronic resource] / O. G. Khomutov, V. I. Filyakova, K. I. Pashkevich> // Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya). - 1996. - Vol. 45, № 11. - P2654-2655 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: The N-alkylamides of 3-fluoroalkylaziridine-2-carboxylic acids have been prepared for the first time by the interaction of ethyl 0-fltioroalkyl-,-dibromocarboxylates with primary amines?? \\\\Expert2\\nbo\\Russian Chemical Bulletin\\1996, 45 (11), 2654.pdf |
S 98 Synthesis and tautomeric equilibrium of 2,6-bis(trifluoroacetyl)cyclohexanone [Electronic resource] / D. V. Sevenard, O. G. Khomutov, M. I. Kodess, K. I. Pashkevich> // Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya). - 1999. - Vol. 48, № 2. - P400-401 Рубрики: ХИМИЧЕСКИЕ НАУКИ \\\\Expert2\\nbo\\Russian Chemical Bulletin\\1999, 48 (2), 400.pdf |
A 53 An efficient synthesis of alkylfluoroalkylketones [Text] / O. G. Khomutov, V. I. Filyakova, A. V. Kutchin, K. I. Pashkevich> // Journal of Fluorine Chemistry. - 1992. - Vol. 58, № 2-3. - P161 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: Interaction of fluoroacyl chlorides with lithium tetraalkylaluminates II prepared by the hydroalumination of alkenes I results in fluorinated ketones III with yields of 65–70%.??RF = CF3, H(CF2)2, C4F9, C6F13 R1 = C3H7, C4H9, C6H13, C7H15??The reaction is simple and does not require an argon atmosphere, as is needed for most reactions of organoaluminum compounds???? |
K 42 Khomutov, O. G. Selective reduction of derivatives of fluorinated beta-diketones [Text] / O. G. Khomutov, V. I. Filyakova, K. I. Pashkevich> // Journal of Fluorine Chemistry. - 1992. - Vol. 58, № 2-3. - P351 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: The reduction of fluorinated ?-diketones (DK) is known to give ?-diols [G. Swalens, M. Anteunis and D. Tavernier, Bull. Soc. Chim. Belg., 79 (1970) 441–450] and ?-hydroxyketones (HK) II [A.L. Henne and P.E. Hinkamp, J. Am. Chem. Soc., 76 (1954) 5147]. We have established that the lithium salts (Ia) as well as chelate compounds of DK with zinc (Ib) and aluminium (Ic) undergo selective reduction with LiAlh4 to HK III. Salts (Id) and chelate compounds (If) are not reduced under the same conditions |
R 30 Reaction of 2-(polyfluoroacyl)cycloalkanones with hydroxylamine [Text] / D. V. Sevenard, O. G. Khomutov, K. I. Pashkevich, E. Lork, G. -V. Roeschenthaler> // Helvetica Chimica Acta. - 2002. - Т. 85, № 7. - P1960-1972. - Библиогр.: с. Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: The 2-acylcycloalkanones 1a-g and 3a-c, possessing a polyfluoroalkyl group, react with hydroxylamine regio- and stereoselectively to yield 4,5-dihydroisoxazol-5-ols 2a-g and 4a-c, respectively, i.e., products of N-addition to the oxo group at the cycloalkane ring (Schemes 1 and 2). The products 2 and 4 can be dehydrated under drastic conditions only (Schemes 3 and 4). The structure of one of the 4,5-dihydroisoxazol-5-ols was confirmed by X-ray crystal-structure analysis |