S 98 Synthesis of fluoroalkyl-containing 2-oxyimino-1,3-dicarbonyl compounds and their reaction with hydrazine hydrate [Text] / V. I. Saloutin, Ya. V. Burgart, Z. E. Skryabina, O. G. Kuzueva // Journal of Fluorine Chemistry. - 1997. - Vol. 84, N 2. - P107-111 Рубрики: ХИМИЧЕСКИЕ НАУКИ |
H 62 Heterocyclization of Fluorinated Di- and Tricarbonyl Compounds [Text] : доклад, тезисы доклада / Ya. V. Burgart, O. G. Kuzueva, A. S. Fokin, V. I. Saloutin // International Memorial I.Postovsky Conference on Organic Chemisty, Ekaterinburg, March 17-20, 1998 : program and abstracts. - Ekaterinburg, 1998. - P51 Рубрики: ХИМИЧЕСКИЕ НАУКИ |
B 57 Biginelli condensations of fluorinated 3-oxo esters and 1,3-diketones [Text] / V. I. Saloutin, Ya. V. Burgart, O. G. Kuzueva, C. O. Kappe, O. N. Chupakhin // Journal of Fluorine Chemistry. - 2000. - Vol. 103, № 3. - P17-23 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: Condensation of fluorinated 3-oxo esters or 1,3-diketones with benzaldehyde and (thio)urea results in the diastereoselective formation of 4-fluoroalkyl-4-hydroxy-2-oxo(thioxo)-6-phenyl-hexahydropyrimidine-5-carboxylates from which by dehydration under acidic conditions the corresponding 6-fluoroalkyl-2-oxo(thioxo)-4-phenyl-1,2,3,4-tetrahydropyrimidine-5-carboxylates were obtained. Under the same conditions, hexafluoroacetylacetone furnishes 4,6-dihydroxy-4,6-di(trifluoromethyl)-hexahydropyrimidin-2-one. Some further reactions of these pyrimidine derivatives leading to fused heterocycles are described.???? |
U 52 Unexpected synthesis of 3,5-diethoxycarbonyl-2-pentafluorophenyl-4-phenyl-7,8,9,10-tetrafluoro-4,5-dihydrobenzo[b]oxacin-6-one [Electronic resource] / Ya. V. Burgart, M. V. Pryadeina, O. G. Kuzueva, M. I. Kodess, V. I. Saloutin, O. N. Chupakhin // Mendeleev Communications. - 2001. - Vol. 11, № 3. - P119-120 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: The reaction of ethyl pentafluorobenzoylacetate with benzaldehyde in the presence of a base affords 3,5-diethoxycarbonyl-2-pentafluorophenyl-4-phenyl-7,8,9,10-tetrafluoro-4,5-dihydrobenzo[b]oxacin-6-one in contrast to fluoroalkyl-containing 3-oxo esters yielding 3,5-dialkoxycarbonyl-2,6-dihydroxy-2,6-difluoroalkyl-4-phenyltetrahydropyranes under the same conditions???? |
R 30 Reactions of fluorine-containing 3-oxo esters with aldehydes [Text] / M. V. Pryadeina, O. G. Kuzueva, Ya. V. Burgart, V. I. Saloutin, K. A. Lyssenko, M. Yu. Antipin // Journal of Fluorine Chemistry. - 2002. - Vol. 17, № 1. - P1-7 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: Fluoroalkylcontaining 3-oxo esters react with aldehydes to form 2-benzylidene-3-fluoroacyl-esters or 4-aryl(alkyl)-3,5-dialkoxycarbonyl-2,6-dihydroxy-2,6-di(fluoroalkyl)tetrahydropyranes depending on the conditions. Ethyl pentafluorobenzoylacetoacetate with benzaldehyde affords 3,5-diethoxy-carbonyl-4-phenyl-2-pentafluorophenyl-7,8,9,10-tetrafluoro-4,5-dihydrobenzo[b]oxacin-6-one |
S 98 Synthesis of fluorinated 2(3)-arylhydrazones of 1,2,3-tri(1,2,3,4-tetra)carbonyl compounds and their heterocyclization reactions [] / Ya. V. Burgart, A. S. Fokin, O. G. Kuzueva, O. N. Chupakhin, V. I. Saloutin // Journal of Fluorine Chemistry. - 1998. - Vol. 92, № 2. - С. 101-108 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: New fluorinated 2-arylhydrazones of 1,2,3-triketones, 2-arylhydrazone-1,2,3-diketo esters and 3-arylhydrazone-1,2,3,4-triketo esters have been prepared by the coupling of fluorine-containing 1,3-keto esters, 1,3-diketones, acyl(aroyl)pyruvic esters and their chelates with aryldiazonium chlorides. The arylhydrazones react with hydrazine hydrate, phenylhydrazine, thiosemicarbazide and hydroxylamine to form the corresponding pyrazole and isoxazole derivatives. Interaction of 3-arylhydrazone-1,2,3,4-diketo esters with o-phenylenediamine results in quinoxaline products. Intramolecular cyclization of the arylhydrazones with pentafluorophenyl substituents leads to cinnolone derivatives |
F 70 Fluorocontaining 1,3-Dicarbonyl Compounds in the Synthesis of Pyrimidine Derivatives ?? [Electronic resource] / Ya. V. Burgart, O. G. Kuzueva, M. V. Pryadeina, C. O. Kappe, V. I. Saloutin // Russian Journal of Organic Chemistry (Translation of Zhurnal Organicheskoi Khimii). - 2001. - Vol. 37, № 6. - P869-880 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: Hexafluoroacetylacetone reacts with urea (thiourea) to yield respectively 4,6-bis(hydroxy)-4,6-bis(trifluoromethyl)hexahydropyrimidin-2-one(thione). The dehydration of the products and also reaction of nonsymmetrical fluoroalkyl-containing 1,3-diketones with urea (thiourea) afford substituted pyrimidines. The condensation of fluorinated 3-oxoesters and 1,3-diketones with benzaldehyde and urea (thiourea) results in 5-alkoxycarbonyl(acyl)-4-hydroxy-2-oxo(thioxo)-6-phenyl-4-fluoroalkylhexahydropyrimidines that on dehydration furnish 5-alkoxycarbonyl(acyl)-2-oxo(thioxo)-4-phenyl-6-fluoroalkyltetrahydropyrimidines. Ethyl 7-nonafluorobutyl-5-phenyl-2,3-dihydrothiazolo[3,2-a]pyrimidine-6-carboxylate hydrobromide forms in reaction of dibromoethane with ethyl ether of 2-thioxo-4-phenyl-6-nonafluorobutyltetrahydropyrimidine \\\\Expert2\\nbo\\Russian Journal of Organic Chemistry\\2001, 37 (6), 869.pdf |
R 30 Reaction of Fluoro-containing 3-Oxoesters with Benzaldehyde [Electronic resource] / M. V. Pryadeina, O. G. Kuzueva, Ya. V. Burgart, V. I. Saloutin // Russian Journal of Organic Chemistry (Translation of Zhurnal Organicheskoi Khimii). - 2002. - Vol. 38, № 2. - P224-231 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: Fluorinated 3-oxoesters in reactions with benzaldehyde depending on conditions afford either 2-benzylidene-3-fluoroalkyl-3-oxoesters or 3,5-dialkoxycarbonyl-2,6-dihydroxy-2,6-difluoroalkyl-4-phenyltetrahydropyrans. The latter were also obtained by treating 3-oxoesters with 2-benzylidene-3-oxoesters. Pentafluorobenzoylacetate with benzaldehyde furnishes 3,5-diethoxycarbonyl-2-pentafluorophenyl-4-phenyl-7,8,9,10-tetrafluoro-4,5-dihydrobenzo[b]oxacin-6-one \\\\Expert2\\nbo\\Russian Journal of Organic Chemistry\\2002, 38 (2), 224.pdf |
K 96 Kuzueva, O. G. Synthesis of 2-arylhydrazones of aliphatic fluorine-containing 1,2,3-tricarbonyl compounds and their reactions with dinucleophiles [Electronic resource] / O. G. Kuzueva, Ya. V. Burgart, V. I. Saloutin // Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya). - 1998. - Vol. 47, № 4. - P673-678 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: New fluorinated 2-arylhydrazones of 1,2,3-tricarbonyl compounds were obtained by coupling fluorine-containing 3-oxo esters, 1,3-diketones, and their copper chelates with aryldiazonium chlorides. Reactions of these arylhydrazones with hydrazine hydrate, phenylhydrazine, thiosemicarbazide, and hydroxylamine gave the corresponding pyrazole and isoxazole derivatives \\\\Expert2\\nbo\\Russian Chemical Bulletin\\1998, 47 (4), 673.pdf |
S 98 Synthesis of fluorine-containing alkyl 2-cyano-3-oxocarboxylates. Reactions with nucleophiles [Electronic resource] / O. G. Kuzueva, Ya. V. Burgart, V. I. Saloutin, O. N. Chupakhin // Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya). - 1999. - Vol. 48, № 10. - P1937-1941 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: Fluorine-containing alkyl 2-cyano-3-oxocarboxylates were synthesized for the first time by the reaction of ethyl cyanoacetate with fluorine-substituted carboxylic acid halides or alkyl carboxylates. The reactions with hydrazine hydrate, phenylhydrazine, ando-phenylenediamine give hydrazinium (ammonium) enolates or products of acid decomposition \\\\Expert2\\nbo\\Russian Chemical Bulletin\\1999, 48 (10), 1937.pdf |