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1.
Инвентарный номер: нет.
   
   R 95

    Rusinov, V. L.
    Fluorinated Triazines / V. L. Rusinov, E. V. Nosova, V. N. Charushin // Fluorine in Heterocyclic Chemistry : Издательство "Springer", 2014. - Vol. 2. - С. 673-716. - Bibliogr. : p. 715-716 (119 ref.)
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
SYNTHETIC ROUTES -- 1,2,3-TRIAZINES -- 1,2,4-TRIAZINES -- 1,3,5-TRIAZINES
Аннотация: In this chapter data on structure, synthetic routes, reactivity of derivatives of 1,2,3-triazines, 1,2,4-triazines and 1,3,5-triazines − bearing one or several fluorine atoms in heterocyclic ring as well as trifluoromethyl substituted triazines are considered and analyzed, and also their certain representatives are discussed

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2.
Инвентарный номер: нет.
   
   C 47

    Charushin, V. N.
    Fluoroquinolones: Synthesis and Application / V. N. Charushin, E. V. Nosova, G. N. Lipunova // Fluorine in Heterocyclic Chemistry : Издательство "Springer", 2014. - Vol. 2. - С. 111-179. - Bibliogr. : p. 176-179 (377 ref.)
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
QUINOLONE SYSTEM -- BIOLOGICAL ACTIVITY -- FLUOROQUINOLONES
Аннотация: The data on 6-fluorо-1,4-dihydroquinolin-4-oxo-3-carboxylic acids and their structural analogues accumulated in the literature for the last 10–15 years are reviewed. Synthetic approaches to the quinolone system, as well as all kind of structural modifications by incorporating substituents into 1–8 positions or by means of annelation have been discussed. The “structure-activity” relationships for antibacterial fluoroquinolones, as well as the data on other types of biological activity for the family of bi- and polycyclic fluoroquinolones are presented. The formation of complexes of fluoroquinolones with metals and their applications have been considered. The bibliography

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3.
Инвентарный номер: нет.
   
   L 79

    Lipunova, G. N.
    Fluorinated Quinolines: Synthesis, Properties and Applications / G. N. Lipunova, E. V. Nosova, V. N. Charushin // Fluorine in Heterocyclic Chemistry : Издательство "Springer", 2014. - Vol. 2. - С. 59-109. - Bibliogr. : p. 108-109 (158 ref.)
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
fLUORINATED QUINOLINES -- SYNTHETIC METHODS -- CYCLOADDITION REACTIONS
Аннотация: The data on the chemistry of fluorinated quinolines available in the literature of the last 10–15 years are presented. A variety of synthetic methods exploiting cyclization and cycloaddition reactions, displacements of halogen atoms or the diaza group, as well as direct fluorinations have been considered. Novel approaches to functionalization of polyfluorinated quinolines, including nucleophilic displacement of fluorine atoms, cross-coupling reactions, and synthesis on the basis of organometallic compounds are discussed. Selected representative examples of fluoroquinolines exhibiting a remarkable biological activity or those quinolines which have already found their applications in medicine will also be discussed in the text. The bibliography

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4.
Инвентарный номер: нет.
   
   S 98

   
    Synthesis of 7-cycloalkylimino substituted 3-amino-6-fluoro-2-methyl-3H-quinazolin-4-ones / E. V. Nosova, G. N. Lipunova, P. A. Slepukhin, V. N. Charushin // Journal of Fluorine Chemistry. - 2012. - in Press online 17 October
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
FLUORINE-CONTAINING QUINAZOLINONES -- 3-AMINOQUINAZOLIN-4-ONES -- NUCLEOPHILIC DISPLACEMENT REACTIONS
Аннотация: A versatile pathway for the synthesis of 7-cycloalkylimino substituted 3-amino-6-fluoro-2-methyl-3H-quinazolin-4-ones from 4,5-difluoroanthranylic acid has been advanced. Nucleophilic amination–defluorination reaction of the 6,7-difluoro derivative of 3-amino-2-methyl-3H-quinazolin-4-one has been established to occur at position 7, as shown by X-ray crystallographic analysis

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5.
Инвентарный номер: нет.
   
   S 98

   
    Synthesis and antitumor activity of fluorinated derivatives of [i,j]-annelated quinolones [Electronic resource] / G. N. Lipunova, E. V. Nosova, L. P. Sidorova, V. N. Charushin // Pharmaceutical Chemistry Journal. - 2011. - Vol. 45, № 4. - P208-210 : ил. - Bibliogr. : p. 210 (7 ref.)
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Аннотация: Tri- and pentacyclic fluoroquinolones were synthesized by intramolecular cyclization of the corresponding 3-hydrazinopolyfluorobenzoylacrylates followed by substitution of fluorine atoms by amine residues. The antitumor activity of the resulting compounds was studied at the National Cancer Institute using cultures of 60 cell lines of nine groups, including leukemia, lung tumor, large intestine tumor, CNS tumor, melanoma, ovary tumor, renal tumor, prostate tumor, and breast tumor. Relationships between structure and antitumor activity were analyzed. In vivo experimental data from hollow fiber tests are presented for two derivatives

\\\\Expert2\\nbo\\Pharmaceutical Chemistry Journal\\2011, 45 (4), 208.pdf
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6.
Инвентарный номер: нет.
   
   T 86

   
    Trialkyl borate assisted amination of fluorinated 1,3-diketones for synthesis of N,N?-1,2-phenylen-bis(beta-aminoenones) and their Ni(II), Cu(II) and Pd(II) complexes [Text] / D. L. Chizhov, M. G. Pervova, M. A. Samorukova, E. F. Khmara, V. I. Filyakova, V. I. Saloutin, V. N. Charushin // Journal of Fluorine Chemistry. - 2011. - Vol. 132, № 6. - P394-401. - Bibliogr. : p. 401 (19 ref.)
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Аннотация: An effecient synthetic method for fluorinated tridentate ?-aminoenones and tetradentate bis(?-aminoenones) via amination of fluorinated 1,3-diketones with o-phenylenediamine in the presence of trialkyl borates was developed. Ni(II), Cu(II) and Pd(II) complexes with tetradentate bis(?-aminoenones) were obtained. Their gaschromatographic behaviour and main fragmentation paths in the electron ionization mass spectra were described

\\\\Expert2\\nbo\\Journal of Fluorine Chemistry\\2011, v. 132, p.394.pdf
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7.
Инвентарный номер: нет.
   
   S 98

   
    Synthesis and fluorescent properties of 2-styryl-6,7-difluoro-8-hydroxyquinoline and its Zn(II) complex [Электронный ресурс] / E. V. Nosova, T. V. Stupina, G. N. Lipunova, V. N. Charushin // Journal of Fluorine Chemistry. - 2013. - Vol.150. - P36-38
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
STYRYLQUINOLINE -- Zn(II) COMPLEX -- fLUORINATED QUINOLINES
Аннотация: A synthetic approach to 2-methyl-6,7-difluoro-8-hydroxyquinoline, a key intermediate, has been developed. 6,7-Difluoro derivative of 2-styryl substituted 8-hydroxyquinoline and its Zn(II) complex have been obtained. Effects of fluorine atoms in the benzene ring on photophysical properties of 2-styryl-8-hydroxyquinolines and their Zn(II) complexes have been studied

\\\\Expert2\\NBO\\Journal of Fluorine Chemistry\\2013, v. 150, p.36.pdf
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8.
Инвентарный номер: нет.
   
   S 98

   
    Synthesis of 7-cycloalkylimino substituted 3-amino-6-fluoro-2-methyl-3H-quinazolin-4-ones [Electronic resource] / E. V. Nosova, G. N. Lipunova, P. A. Slepukhin, V. N. Charushin // Journal of Fluorine Chemistry. - 2013. - Vol.145. - P63-65
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
SYNTHESIS -- NUCLEOPHILIC SUBSTITUTION -- X-RAY ANALYSIS
Аннотация: A versatile pathway for the synthesis of 7-cycloalkylimino substituted 3-amino-6-fluoro-2-methyl-3H-quinazolin-4-ones from 4,5-difluoroanthranylic acid has been advanced. Nucleophilic amination–defluorination reaction of the 6,7-difluoro derivative of 3-amino-2-methyl-3H-quinazolin-4-one has been established to occur at position 7, as shown by X-ray crystallographic analysis. --------------------------------------------------------------------------------

\\\\Expert2\\NBO\\Journal of Fluorine Chemistry\\2013, v. 145, p.63.pdf
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9.
Инвентарный номер: нет.
   
   S 98

   
    Synthesis and antiviral activity of fluorine-containing 4-arylaminoquinazolines / G. N. Lipunova, E. V. Nosova, A. A. Laeva, V. N. Charushin // Pharmaceutical Chemistry Journal. - 2012. - Vol.45, №12. - С. 709-711
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
ANTIVIRAL ACTIVITY -- 4-ARYLAMINOQUINAZOLINES -- INTRAMOLECULAR CYCLIZATIONS
Аннотация: 2-Methylthio-4-phenylamino-6,7,8-trifluoro-3H-quinazolin-4-one was synthesized by means of intramolecular cyclizations of S-methyl-N-(tetrafluorobenzoyl)isothiourea followed by a reaction with POCl3 and nucleophilic substitution at the 4-position. The reactions of the synthesized compound with amines proceed, depending on their nature, via substitution of either the F(7) atom or the SMe fragment in the 2-position. The antiviral activity of the obtained 6,7,8-trifluoro-2-ethylthioquinazolin-4-ones was investigated using monkeypox virus, smallpox vaccine, and ectromelia virus. It is shown that fluorinated quinazoline derivatives have good prospects in the search for new active substances

\\\\Expert2\\nbo\\Pharmaceutical Chemistry Journal\\2012, 45 (12), 709.pdf
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10.
Инвентарный номер: нет.
   
   F 70

   
    Fluorine-containing heterocycles. XVIII. Monofluoro derivatives of quinazolines and 1,3-benzothiazin-4-ones [Electronic resource] / E. V. Nosova, A. A. Laeva, T. V. Trashakhova, A. V. Golovchenko, G. N. Lipunova, P. A. Slepukhin, V. N. Charushin // Russian Journal of Organic Chemistry (Translation of Zhurnal Organicheskoi Khimii). - 2009. - Vol. 45, № 6. - P904-912
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Аннотация: 5- and 7-Fluoro-substituted quinazolines and 1,3-benzothiazin-4-ones were synthesized starting from 2-amino-6-fluorobenzonitrile and mono- and difluoro-substituted benzoic acid derivatives. The reactivities of di- and tetrafluoro-substituted benzoyl chlorides and benzoyl isothiocyanates in cyclocondensations leading to fluorinated quinazolines and 1,3-benzothiazines were compared

\\\\Expert2\\nbo\\Russian Journal of Organic Chemistry\\2009, 45 (6), 904.pdf
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11.
Инвентарный номер: нет.
   
   S 89

   
    Structures of Ni(II), Pd(II) and Cu(II) complexes with 1,2-bis(5,5,5-trifluoro-4-oxopent-2-en-2-amino)benzene [Electronic resource] / D. L. Chizhov, E. F. Khmara, P. A. Slepukhin, V. I. Filyakova, V. N. Charushin // Journal of Structural Chemistry. - 2010. - Vol. 51, № 2. - P288-295
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
Cu(II) COMPLEXES -- SYNTHESIS -- X-RAY CRYSTALLOGRAPHY ????
Аннотация: A new fluorine-containing tetradentate ligand 1,2-bis(5,5,5-trifluoro-4-oxopent-2-en-2-amino)benzene and its complexes with Ni(II), Pd(II) and Cu(II) are characterized by single crystal X-ray diffraction. It is found that the enaminoketone fragments of the ligand are identical in bond lengths and angles; they are almost planar, and make the angles of 51.3° to the plane of the benzene ring. The structures of Ni(II), Pd(II), and Cu(II) complexes are similar and have a saddle-shape configuration. The metal ions have square planar coordination and are located almost in the center of the N2O2 square. The average M-N bond lengths are longer than M-O ones by 0.014 A and 0.034 A for the Ni(II) and Cu(II) complexes respectively, while in the Pd(II) complex, M-O is longer than M-N by 0.029 A. The average chelate angles N-M-O in the complexes are: N-Ni-O 95.12°; N-Pd-O 95.68°; N-Cu-O 93.88

\\\\Expert2\\nbo\\Journal of Structural Chemistry\\2010, V. 51, N 2, p.288-295.pdf
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12.
Инвентарный номер: нет.
   
   F 70

   
    Fluorinated azines and benzazines containing oxygen or sulfur atoms [Text] / E. V. Nosova, G. N. Lipunova, V. N. Charushin, O. N. Chupakhin // Journal of Fluorine Chemistry. - 2010. - Vol. 131, № 12. - P1267-1288
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Аннотация: In the frames of this review article the recently obtained data on synthetic approaches to fluorinated oxa(thia)azines and benzazines, their chemical properties, structure, and biological activity have been analyzed

\\\\Expert2\\nbo\\Journal of Fluorine Chemistry\\2010, v. 131, p.1267.pdf
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13.
Инвентарный номер: нет.
   
   P 80

   
    Polyfluorobenzoyl chlorides and isothiocyanates in reactions with CH-reactive benzimidazoles [Electronic resource] / E. V. Nosova, G. N. Lipunova, A. A. Laeva, V. N. Charushin // Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya). - 2005. - Vol. 54, № 3. - P733-737
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Аннотация: Reactions of 2-benzoylmethylbenzimidazole with tetra- and pentafluorobenzoyl chlorides afford fluorine-containing 6-benzoyl-7H-benzimidazo[3,2-a]quinolones. 2-Cyanomethyl- or 2-benzoylmethylbenzimidazole reacts with tetra(penta) fluorobenzoyl isothiocyanates to give fluorine containing 1,3-benzothiazinones, which differently behave in reactions with cycloalkylimines

\\\\Expert2\\nbo\\Russian Chemical Bulletin\\2005, 54 (3), 733.pdf
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14.
Инвентарный номер: нет.
   
   F 98

   
    Fused polycyclic nitrogen-containing heterocycles. 21. Condensation of 4-hydroxy-3,5-diphenyl-2-phenyliminothiazolidine with 5-fluoro-4-morpholino- and 4-(4-methylpiperazino)-1,2-phenylenediamines [Electronic resource] / V. A. Mamedov, N. A. Zhukova, T. N. Beschastnova, A. A. Balandina, A. T. Gubaidullin, S. K. Kotovskaya, Sh. K. Latypov, Ya. A. Levin, V. N. Charushin // Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya). - 2009. - Vol. 58, № 1. - P203-211
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Аннотация: The condensation of 4-hydroxy-3,5-diphenyl-2-phenyliminothiazolidine with 5-fluoro-4-morpholino- and 5-fluoro-4-(4-methylpiperazino)-1,2-phenylenediamines leads to region-isomeric thiazolo[3,4-a]quinoxalines differing in substituents in positions 7 and 8 of the benzene ring. From the ratio of isomers formed it follows that the mesomeric effect of a fluorine atom in 1,2-phenylenediamines is comparable with the influence of an aminosubstituent

\\\\Expert2\\nbo\\Russian Chemical Bulletin\\2009, 58 (1), 203-211.pdf
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15.
Инвентарный номер: нет.
   
   S 98

   
    Synthesis of fluorine-containing quinoline-2,3-dicarboxylates from products of vicarious nucleophilic substitution of hydrogen in 3-fluoronitroarenes [Electronic resource] / S. K. Kotovskaya, G. A. Zhumabaeva, V. N. Charushin, O. N. Chupakhin // Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya). - 2009. - Vol. 58, № 1. - P170-175
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Аннотация: The reactions of 3-fluoro-4-R-6-phenylsulfonylmethylnitrobenzenes with dimethyl fumarate or diethyl maleate in acetonitrile in the presence of an excess of K2CO3 and a catalytic amount of 18-crown-6 afforded mixtures of dialkyl 6-R-7-fluoro- and dialkyl 6-R-7-phenylsulfonylquinoline-2,3-carboxylate N-oxides, as well as dialkyl 6-R-7-fiuoro- quinoline-2,3-carboxylates (alkyl is methyl or ethyl), which were resolved by column chromatography and identified by 1H NMR spectroscopy and X-ray diffraction

\\\\Expert2\\nbo\\Russian Chemical Bulletin\\2009, 58 (1), 170-175.pdf
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16.
Инвентарный номер: нет.
   
   F 70

   
    Fluorine-containing quinazolines annulated at the pyrimidine ring [Electronic resource] / E. V. Nosova, A. A. Laeva, T. V. Trashakhova, G. N. Lipunova, P. A. Slepukhin, V. N. Charushin // Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya). - 2009. - Vol. 58, № 6. - P1303-1308
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Аннотация: Fluorine-containing quinazolines annulated at the sides [a] and [c] were synthesized by the reaction of 2- and 4-hydrazino-substituted quinazolines with aldehydes and subsequent oxidative cyclization. Annulation at the side [b] was performed by alkylation of 2-alkylthio-4(3H)-quinazolinones with bromoethanol and ipso-substitution of the alkylthio group

\\\\Expert2\\nbo\\Russian Chemical Bulletin\\2009, 58 (6), 1303-1308.pdf
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17.
Инвентарный номер: нет.
   
   S 98

   
    Synthesis and antiviral activity of fluorinated 3-phenyl-1,2,4- benzotriazines [Электронный ресурс] / S. K. Kotovskaya, G. A. Zhumabaeva, N. M. Perova, Z. M. Baskakova, V. N. Charushin, O. N. Chupakhin, E. F. Belanov, O. A. Serova // Pharmaceutical Chemistry Journal. - 2007. - Vol.41, №2. - P62-68
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
CYCLIZATION -- CYTOTOXICITY -- FLUORINATION
Аннотация: New synthetic approaches to fluorinated 3-phenyl-1,2,4-benzotriazines for biological testing have been elaborated. 1-(3,4-Difluorophenyl)-3,5- diphenylformazan (IVa) was synthesized via dinitriding of 3,4-difluoroaniline, followed by azo-addition of the resulting azobenzenediazonium chloride with acetaldehyde phenylhydrazone. 6,7-Difluoro-3-phenyl-1,2,4-benzotriazine (Va) was obtained via intramolecular cyclization of formazan IVa in the presence of BF3/AcOH complex. Monofluoro-substituted 6-R-7-fluoro-3-phenyl-1,2,4- benzotriazine derivatives (Vb-Vq) were prepared by substituting fluorine atom with alkoxides in 3,4-difluoronitrobenzene. Conditions for nucleophilic substitution of the second fluorine atom in benzotriazines V have been established. Fluorinated 3-phenyl-1,2,4-benzotriazines have been tested for antiviral and cytotoxic activity on Vero cell cultures and proved to be active against severe diseases caused by smallpox and some other pathogenic viruses

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18.
Инвентарный номер: нет.
   
   C 51

   
    Chemoenzymatic Synthesis and Antiherpes Activity of 5-Substituted 4,6-Difluorobenzimidazoles Ribo- and 2′-Deoxyribonucleosides [Электронный ресурс] / M. I. Kharitonova, I. V. Fateev, A. L. Kayushin, I. D. Konstantinova, S. K. Kotovskaya, V. L. Andropova, G. A. Galegov, V. N. Charushin, A. I. Miroshnikov // Synthesis (Germany). - 2016. - Vol. 48, № 3. - С. 394-406. - Bibliogr. : p. 405-406 (37 ref.)
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
DRUG DISCOVERY- -- NUCLEOSIDES -- HERPES SIMPLEX VIRUS
Аннотация: A series of 5,6-disubstituted benzimidazole nucleosides, obtained earlier, did not show any significant antiviral activity at relatively low cytotoxicity in vitro. In the course of our research we have succeeded in introducing an additional fluorine atom into the benzimidazole ring system. A new series of 4,6-difluorobenzimidazoles, bearing various groups (fluoro-, methoxy-, ethoxy-, morpholino-, and pyrrolidino-) in the 5-position of the benzene ring, have been synthesized. All these compounds proved to be substrates for recombinant E. coli purine nucleoside phosphorylase (PNP) in the transglycosylation reaction. Effective methods for the synthesis of ribo- and 2′-deoxyribonucleosides with high yields (60–90%) have been described, and the formation of regioisomeric N3-nucleosides of benzimidazoles have been detected. The biological activity of the nucleosides obtained against herpes simplex virus type 1 (HSV-1) has been elucidated. All compounds show a low cytotoxicity in the cell culture Vero E6. 4,5,6-Trifluoro-1-(β-d-ribofuranosyl)benzimidazole and 5-methoxy-4,6-difluoro-1-(β-d-2′-deoxyribofuranosyl)benzimidazole proved to inhibit completely the progression of the virus cytopathic effect (CPE) at a multiplicity of infection (MOI) of 0.01 PFU/cell.

\\\\expert2\\nbo\\Synthesis\\2016, v. 48. p.394-406.pdf
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19.
Инвентарный номер: нет.
   
   S 98

   
    Synthesis, structure and photoluminescent properties of BF2 and BPh2 complexes with N,O-benzazine ligands [Electronic resource] / E. V. Nosova, T. N. Moshkina, G. N. Lipunova, I. V. Baklanova , P. A. Slepukhin, V. N. Charushin // Journal of Fluorine Chemistry. - 2015. - Vol. 175. - С. 145-151. - Bibliogr. : p. 150-151 (29 ref.)
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
N,O-BIDENTATE LIGANDS -- BPh2 COMPLEXES -- BF2 COMPLEXES
Аннотация: Novel N,O-bidentate BF2 and BPh2 complexes have been prepared in good to excellent yields through coordination of 8-hydroxy-2-methylquinolines and 2-(2-hydroxyphenyl)-3H-quinazolin-4-ones with boron trifluoride etherate or triphenylborane under mild conditions. All complexes have been characterized by H-1, B-11 and F-19 NMR, mass-spectrometry and X-ray crystallography data. Some complexes have been found to exhibit a significant fluore.scence in acetonitrile solutions. Electronic and site effects of substituents in both heterocyclic and phenol fragments proved to have a profound impact on quantum yields.

\\\\expert2\\nbo\\Journal of Fluorine Chemistry\\2015,V.175, p.145-151.pdf
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20.
Инвентарный номер: нет.
   
   F 70

   
    Fluorine-containing pyrazoles and their condensed derivatives: Synthesis and biological activity [Electronic resource] / G. N. Lipunova, E. V. Nosova, V. N. Charushin, O. N. Chupakhin // Journal of Fluorine Chemistry. - 2015. - Vol. 175. - С. 84-109. - Bibliogr. : p. 108-109 (119 ref.)
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
HETEROCYCLIC-COMPOUNDS -- NUCLEOPHILES -- IDENTIFICATION
Аннотация: In the frames of this review article the recently obtained data on new synthetic approaches to fluorinated pyrazoles and their condensed analogs, as well as their biological activities have been analyzed.

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