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1.
Инвентарный номер: нет.
   
   D 62


   
    Direct fusion of a triazine to a pyrazine ring. Synthesis of derivatives of [1,2,4]triazino[5,6-b]quinoxaline [Electronic resource] / V. N. Charushin, V. G. Baklykov, O. N. Chupakhin, L. M. Naumova // Chemistry of Heterocyclic Compounds. - 1984. - Vol. 20, № 9. - P1057-1058. - Bibliogr. : p. 1058 (2 ref.)
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
TRIAZINES -- PYRAZINES

\\\\expert2\\nbo\\Chemistry of Heterocyclic Compounds\\1984, v.20, N 9, p. 1057.pdf
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2.
Инвентарный номер: нет.
   
   A 32


    Alekseev, S. G.
    New type of transformation of a 1,2,4-triazine ring to pyrazine derivatives (Letter) [Electronic resource] / S. G. Alekseev, V. N. Charushin, O. N. Chupakhin // Chemistry of Heterocyclic Compounds. - 1987. - Vol. 23, № 2. - С. 238-239. - Bibliogr. : p. 239 (6 ref.)
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
PYRAZINE DERIVATIVES -- 1,2,4-TRIAZINES

\\\\expert2\\nbo\\Chemistry of Heterocyclic Compounds\\1987, v.23, N 2, p. 238.pdf
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3.
Инвентарный номер: нет.
   
   R 30


   
    Reactions of azinium cations. 8. Electron structures of 3-substituted 1,2,4-triazines and protonation, quaternization, and reactions with nucleophiles [Electronic resource] / S. G. Alekseev, P. A. Torgashev, M. A. Fedotov, A. I. Rezvukhin, S. V. Shorshnev, A. V. Belik, V. N. Charushin, O. N. Chupakhin // Chemistry of Heterocyclic Compounds. - 1988. - Vol. 24, № 4. - С. 434-441. - Bibliogr. : p. 440-441 (34 ref.)
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
1,2,4-TRIAZINES -- NUCLEOPHILES
Аннотация: The electron structures of 3-substituted 1,2,4-triazines and isomeric N-methyltriazinium salts were calculated by the CNDO/2 method. The results of the calculations were compared with the parameters of the 13C, 15N, and 14N NMR spectra, as well as with experimental data on the protonation, N-alkylation, and reactions of 1,2,4-triazines with simple nucleophiles. The protonation centers of 1,2,4-triazines were determined by means of 1H, 13C, and 14N NMR spectroscopy. The covalent adducts formed by the proton salts of 3-methoxy-, 3-methylthio-, 3-morpholino-, and 3-pyrrolidino-1,2,4-triazine with water and methanol were recorded by 1H NMR spectroscopy.

\\\\expert2\\nbo\\Chemistry of Heterocyclic Compounds\\1988, v.24, N 4, p. 434.pdf
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4.
Инвентарный номер: нет.
   
   C 98


   
    Cyclizations of 1,2,4-triazinium salts with bifunctional nucleophiles - a new route to condensed 1,2,4-triazines [Electronic resource] / S. G. Alexeev, V. N. Charushin, O. N. Chupakhin, G. G. Alexandrov // Tetrahedron Letters. - 1988. - Vol. 29, № 12. - С. 1431-1434. - Bibliogr. : p. 1434 (6 ref.)
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
1,2,4-TRIAZINIUM SALTS -- AMIDES -- NUCLEOPHILES
Аннотация: The reaction of 1,2,4-triazinium salts with amides of acetoacetic acid yielding 1,4,4a,5,7,7a-hexahydro-6H-pyrrolo[3,2-e]-1,2,4-triazin-6-ones exemplifies the first direct annelation to the 1,2,4-triazine ring based on the diaddition of bifunctional nucleophiles at C-5 and C-6.

\\\\expert2\\nbo\\Tetrahedron Letters\\1988, v 29, p.1431.pdf
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5.
Инвентарный номер: нет.
   
   K 39


   
    Ketenaminals as 1,3-dinucleophiles in the synthesis of condensed 1,4-diazines and 1,2,4-triazines (Letter) [Electronic resource] / V. N. Charushin, S. G. Alexeev, O. N. Chupakhin, H. C. Van der Plas // Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya). - 1989. - Vol. 38, № 2. - С. 438. - Bibliogr. : p. 438 (2 ref.)
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
1,3-DINUCLEOPHILES -- KETENAMINALS

\\\\expert2\\nbo\\Russian Chemical Bulletin\\1989. V. 38, N 2. P. 438.pdf
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6.
Инвентарный номер: нет.
   
   B 39


   
    Behavior of Monocyclic 1,2,4-Triazines in Reactions with C-, N-, O-, and S-Nucleophiles [Electronic resource] / V. N. Charushin, S. G. Alexeev, O. N. Chupakhin, H. C. Van der Plas // Advances in Heterocyclic Chemistry. - 1989. - Vol. 46 (C). - С. 73-142. - Bibliogr. : p. 135-142 (200 ref.)
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
1,2,4-TRIAZINES -- NITROGEN-CONTAINING HETEROCYCLES
Аннотация: Among the six-membered nitrogen-containing heterocycles the 1,2,4-triazines have attracted the attention of chemists for a long time. This is due to the fact that many 1,2,4-triazine derivatives are biologically active and are used in medicine and agriculture. Moreover, 1,2,4-triazines are of chemical interest. They proved to be very susceptible to attack by all kinds of nucleophiles, leading to the addition, and subsequently either substitution or cyclization, and ring transformation. This continuing and lively interest in this area of heterocyclic chemistry has produced a great number of publications and patent applications. This chapter concentrates on the behavior of monocyclic 1,2,4-triazines in reactions with C-, N-, 0-, and S-nucleophiles, because the important features of general character established for simple 1,2,4-triazines can evidently be applied to other derivatives including condensed 1,2,4-triazines.

\\\\expert2\\nbo\\Advances in Heterocyclic Chemistry\\1988. V. 46 (C). P. 73-142.pdf
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7.
Инвентарный номер: нет.
   
   R 30


   
    Reactivity of 3-alkynylthio-1-ethyl-1,2-4-triazinium salts in intramolecular Diels-Alder reactions [Electronic resource] / V. N. Charushin, Beb Van Veldhuizen, Henk C. van der Plas, Casper H. Stam // Tetrahedron. - 1989. - Vol. 45. - С. 6499-6510. - Bibliogr. : p. 6510 (20 ref.)
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
1,2,4-TRIAZINES -- TRIETHYLOXONIUM TETRAFLUOROBORATE -- DIELS-ALDER REACTIONS
Аннотация: Quaternization of 3-(3-butynylthio) and 3-(4-pentynyltio) substituted 1,2,4-triazines with triethyloxonium tetrafluoroborate in CH2Cl2 at room temperature occurs exclusively at N-1 yielding 3-alkynylthio-1-ethyl-1,2,4-triazinium salts, as unequivocally shown by the 13C NMR and X-ray crystallographic data. 3-Alkynylthio-1-ethyl-5-phenyl-1,2,4-triazinium salts undergo the intramolecular Diels-Alder reaction into the corresponding thieno [2,3-b]- and thiopyrano [2,3-b]pyridines under considerably milder conditions than the corresponding neutral 1,2,4-triazines.

\\\\expert2\\nbo\\Tetrahedron\\1989, v. 45, p. 6499.pdf
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8.
Инвентарный номер: нет.
   
   C 98


   
    Cyclization of azinium cations with bifunctional nucleophiles. 27. Actoacetamides in synthesis of derivatives of a new heterocyclic system of pyrrolo[3,2-E]-1,2,4-triazine [Electronic resource] / S. G. Alekseev, V. N. Charushin, O. N. Chupakhin, G. G. Aleksandrov, S. V. Shorshnev, A. I. Chernyshev // Bulletin of the Academy of Sciences of the USSR Division of Chemical Science. - 1989. - Vol. 38, № 7. - С. 1501-1507. - Bibliogr. : p. 1507 (14 ref.)
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
PYRROLO-1,2,4-TRIAZINES -- NUCLEOPHILIC DIADDITION -- ACETOACETOAMIDES
Аннотация: A new approach to the synthesis of condensed pyrrolo-1,2,4-triazines was carried out, based on the nucleophilic diaddition of acetoacetoamides to 1,2,4-triazine derivatives

\\\\expert2\\nbo\\Russian Chemical Bulletin\\1989. V. 38, N 7. P. 1501.pdf
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9.
Инвентарный номер: нет.
   
   О-42


   
    1-Alkyl-1,2,4-triazinium ylides as 1,3-dipoles in a cycloaddition reaction with diethyl acetylenedicarboxylate [Electronic resource] / O. N. Chupakhin, B. V. Rudakov, S. G. Alexeev, S. V. Shorshnev, V. N. Charushin // Mendeleev Communications. - 1992. - N 3. - P85-86 . - ISSN 0959-9436
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
1-АЛКИЛ-1.2.4-ТРИАЗИНИЛИДЫ -- ИЛИДЫ -- ДИПОЛИ -- 1.3-ДИПОЛИ -- ЦИКЛОПРИСОЕДИНЕНИЕ -- ДИЭТИЛАЦЕТИЛЕНДИКАРБОКСИЛАТ -- ДЕПРОТОНАЦИЯ -- 1-АЛКИЛ-5-ФЕНИЛ-1.2.4-ТРИАЗИНА СОЛИ -- триэтиламины -- АЗОМЕТИНИЛИДЫ -- ЦИКЛОПРИСОЕДИНЕНИЕ ДИПОЛЯРНОЕ -- ДИПОЛЯРНОЕ ЦИКЛОПРИСОЕДИНЕНИЕ -- ПИРРОЛО[2.1-F]1.2.4-ТРИАЗИНЫ -- СОЛИ -- ОРГАНИЧЕСКАЯ ХИМИЯ -- ХИМИЯ ОРГАНИЧЕСКАЯ
Аннотация: Deprotonation of 1-alkyl-5-phenyl-1,2,4-triazinium salts by triathylamine results in the formation of azomethyne ylides which undergo a 1,3-dipolar cycloaddition reaction with diethyl acetylenedicarboxylate to yield pyrrolo[2,1-f]1,2,4-triazines

\\\\expert2\\nbo\\Mendeleev Communications\\1992, v.2, N 3. p.85-86.pdf
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10.
Инвентарный номер: нет.
   
   A 10


   
    A simple one pot synthesis of condensed 1,2,4-triazines by using the tandem AN-SNipso and SNH-SNipso reactions [Text] / O. N. Chupakhin, G. L. Rusinov, D. G. Beresnev, V. N. Charushin, H. Neunhoeffer // Journal of Heterocyclic Chemistry. - 2001. - Т. 38, № 4. - P901-907
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Аннотация: A new synthetic approach to condensed 1,2,4-triazines based on using the tandem AN-SNipso and SNH-SNipso reactions has been developed. 5-Methoxy-3-penyl-l,2,4 1,2,4-triazine and its N1-methyl quaternary salt were found to react with C,N-, C,O- and N,N?-bifunctional nucleophiles (m-phenylenediamine, resorcinol, semicarbazide and ureas) into triazacarbazoles, benzofuro[2,3-e][1,2,4]-triazines, and 6-azapurine derivatives. In all cases nucleophiles attack first the unsubstituted C-6 carbon of the triazine ring, while the final stage is replacement of the methoxy group affording cyclization products.

\\\\Cserver\\dist\\НБО\\Электронная библиотека_Библиогр1\\Journal of Heterocyclic Chemistry\\2001.v.38.p.901.Chupachin.pdf
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11.
Инвентарный номер: нет.
   
   I-69


   
    Intermolecular and intramolecular cycloaddition reactions of 1-ethyl-1,2,4-triazinium salts with alkynes [Electronic resource] / N. N. Mochul`skaya, A. A. Andreiko, V. N. Charushin, V. I. Solomonov // Mendeleev Communications. - 2001. - Vol. 11, № 1. - P19-20
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Аннотация: Azomethyne ylides generated from 3-alkylthio substituted 1-alkyl-5-aryl-1,2,4-triazinium salts 4a–c on treatment with triethylamine undergo 1,3-dipolar cycloaddition with dimethyl acetylenedicarboxylate to give pyrrolo[2,1-f] [1,2,4]triazines, while 1-ethyl-5- phenyl-1,2,4-triazinium salts 1a,b bearing the CC bond in the side-chain 3-alkynylthio substituent react with acetylenes to undergo either intermolecular 1,3-dipolar cycloaddition or intramolecular inverse electron demand Diels–Alder reactions????

\\\\expert2\\nbo\\Mendeleev Communications\\2001, v.11, N 1. p.19.pdf
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12.
Инвентарный номер: нет.
   
   U 88


   
    Use of the tandem An-An reactions for the synthesis of condensed 1,2,4-triazines [Text] : доклад, тезисы доклада / V. N. Charushin, N. N. Mochul`skaya, A. A. Andreiko, M. I. Kodess, O. N. Chupakhin // XXth European Colloquium on Heterocyclic Chemistry, Stockholm,Sweden, 18-21 Aug. 2002 г. - Stockholm, 2002. - PA:8
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ

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13.
Инвентарный номер: нет.
   
   U 88


   
    Use of tandem AN-AN reactions for the synthesis of thiazolo[4,5-e]-1,2,4-triazines [Electronic resource] / V. N. Charushin, N. N. Mochul`skaya, A. A. Andreiko, M. I. Kodess, O. N. Chupakhin // Mendeleev Communications. - 2002. - Vol. 12, № 1. - P28-29
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Аннотация: 3-Aryl-1,2,4-triazines react with thioamides in acetic anhydride to produce thiazolo[4,5-e]-1,2,4-triazine derivatives and this reaction represents a new method for the fusion of thiazole and 1,2,4-triazine rings based on the nucleophilic ortho-diaddition type (AN-AN) cyclization reactions??????

\\\\expert2\\nbo\\Mendeleev Communications\\2002, v.12, N 1. p.28.pdf
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14.
Инвентарный номер: нет.
   
   T 19


   
    Tandem AN—AN reactions in the synthesis of 1H-pyrrolo[3,2-e]-1,2,4-triazines and products of their oxidative transformations [Electronic resource] / V. N. Charushin, N. N. Mochul`skaya, A. A. Andreiko, M. I. Kodess, I. A. Litvinov, O. G. Sinyashin, O. N. Chupakhin // Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya). - 2003. - Vol. 52, № 8. - P1740-1749
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Аннотация: The reactions of 3-aryl-1,2,4-triazines with -aminovinyl ketones or ethyl -aminocrotonates in acetic anhydride at room temperature afforded cyclic products of the tandem nucleophilic addition, viz., 3a,4,7,7a-tetrahydro-1H-pyrrolo[3,2-e]-1,2,4-triazines, in good yields. Under oxidative conditions, the latter compounds underwent the pyrrole-ring opening under the action of potassium permanganate to form the corresponding triazinones and were transformed into thriazolyl-substituted pyridines under the action of selenious acid

\\\\Expert2\\nbo\\Russian Chemical Bulletin\\2003, 52 (8), 1740.pdf
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15.
Инвентарный номер: нет.
   
   P 93


   
    Protolytic equilibrium of the isomeric phenyl-1,2,4-triazines [Electronic resource] / I. V. Khabibulina, A.P. Volovodenko, R. E. Trifonov, G. V. Yashukova, N. N. Mochul`skaya, V. N. Charushin, G. L. Rusinov, D. G. Beresnev, N. A. Itsikson, V. A. Ostrovskii // Chemistry of Heterocyclic Compounds. - 2003. - Vol. 39, № 5. - P616-623
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Аннотация: The protonation constants for the first and second stages (pK BH+, pKBH2+) of a series of 1,2,4-triazines with a phenyl substituent at various positions in the ring were determined in aqueous solution by a spectrophotometric method. The values of the basicity constants characterizing the first protonation of the heterocycles investigated was in the range of acidity of the medium of pH 3.5 to H0 -2, and the second from H0 -7.3 to H0 -8.7. The position of the phenyl substituent proved to have a significant effect on the size of pK BH+. According to the results of ab initio calculations using HF/6-31G** for the heterocycles investigated the 1H+ form is thermodynamically most stable among the monocations, with the exception of 6-phenyl-1,2,4-triazine for which the existence of the monocation in the 1H+ and 2H+ forms are equally probable. In the case of the dications of all the triazines the 2,4-H,H2+ tautomer is the most preferred. The aromaticity of the 1,2,4-triazine ring is changed insignificantly on mono- and diprotonation.

\\\\Expert2\\nbo\\Chemistry of Heterocyclic Compounds\\2003, v.39, N 5, p.616. .pdf
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16.
Инвентарный номер: нет.
   
   A 48


   
    Aminovinyl ketones and aminovinyl esters as C---C---N building blocks for the synthesis of 1H-pyrrolo[3,2-e]1,2,4-triazines [Text] / V. N. Charushin, N. N. Mochul`skaya, A. A. Andreiko, T. I. Filyakova, M. I. Kodess, O. N. Chupakhin // Tetrahedron Letters. - 2003. - Vol. 44, № 11. - P2421-2424. - Bibliogr. : p. 2424 (16 ref.)
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Аннотация: 5,6-Unsubstituted-3-aryl-1,2,4-triazines were found to react with aminovinyl ketones and aminovinyl esters in acetic anhydride to form derivatives of 3a,4,7,7a-tetrahydro-1H-pyrrolo[3,2-e]1,2,4-triazines in good yields????

\\\\Expert2\\nbo\\Tetrahedron Letters\\2003. v.44. p.2421.pdf
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17.
Инвентарный номер: нет.
   
   A 60


   
    Annelation of the thiazole ring to 1,2,4-triazines by tandem AN—AN or SNH—SNH reactions [Electronic resource] / N. N. Mochul`skaya, A. A. Andreiko, M. I. Kodess, E. B. Vasil'eva, V. I. Filyakova, A. T. Gubaidullin, I. A. Litvinov, O. G. Sinyashin, G. G. Aleksandrov, V. N. Charushin // Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya). - 2004. - Vol. 53, № 6. - P1279-1289
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Аннотация: The reactions of 3-aryl-1,2,4-triazines with aromatic thioamides and 4-arylthiosemicarbazides in acetic anhydride at room temperature afforded cyclic products of the tandem nucleophilic addition reactions, viz., tetrahydrothiazolo[4,5-e]-annelated 1,2,4-triazines, in good yields. The latter underwent aromatization in the presence of potassium permanganate

\\\\Expert2\\nbo\\Russian Chemical Bulletin\\2004, 53 (6), 1279.pdf
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18.
Инвентарный номер: нет.
   
   O-57


   
    One-Step Heterylation at the Upper Rim of Calix[4]arene with 1,2,4-Triazin-5(2H)-ones [Electronic resource] / D. G. Beresnev, N. A. Itsikson, O. N. Chupakhin, V. N. Charushin, M. I. Kodess, A. I. Butakov, G. L. Rusinov, Yu. Yu. Morzherin, A. I. Konovalov, I. S. Antipin // Journal of Organic Chemistry. - 2006. - Vol. 71, № 21. - P8272-8275
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Аннотация: A convenient way to modify calix[4]arenes based on the direct C-C coupling reaction of their phenol moiety with 1,2,4-triazines has been advanced, and the ability of modified calixarenes to provide transport of La3+ and Ga3+ cations through organic membranes has been examined. ??

\\\\Expert2\\nbo\\Journal of Organic Chemistry\\2006, v.71, N 21, p.8272.pdf
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19.
Инвентарный номер: нет.
   
   S 98


   
    Synthesis of pyridines from 1,2,4-triazines under high pressure [Electronic resource] / M. M. Krayushkin, I. P. Sedishev, V. N. Yarovenko, I. V. Zavarzin, S. K. Kotovskaya, D. N. Kozhevnikov, V. N. Charushin // Russian Journal of Organic Chemistry (Translation of Zhurnal Organicheskoi Khimii). - 2008. - Vol. 44, № 3. - P407-411
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Аннотация: A procedure has been proposed for the synthesis of pyridines from 1,2,4-triazine derivatives and bicyclo[2.2.1]hepta-2,5-diene under high pressure in the presence of lithium perchlorate as catalyst

\\\\Expert2\\nbo\\Russian Journal of Organic Chemistry\\2008, 44 (3), 407.pdf
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20.
Инвентарный номер: нет.
   
   C 47


    Charushin, V. N.
    1,2,4-Triazines and their Benzo Derivatives [] : монография / V. N. Charushin, V. L. Rusinov, O. N. Chupakhin // Comprehensive Heterocyclic Chemistry III : Elsevier : Oxford, 2008. - Vol. 9. - 95-196.
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ

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