Z 99 [4+2] Cycloaddition reactions of 1,2,4,5-tetrazines with allylcarboranes [Electronic resource] / G. L. Rusinov, R. I. Ishmetova, S. G. Tolshchina, N. K. Ignatenko, I. N. Ganebnuikh, P. A. Slepukhin, V. A. Ol'shevskaya, V. N. Kalinin, V. N. Charushin> // Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya). - 2010. - Vol. 59, № 1. - P116-121 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): ALLYLCARBORANES -- PYRIDAZINES -- [4+2] CYCLOADDITION Аннотация: The [4+2] cycloaddition reactions of 3,6-disubstituted 1,2,4,5-tetrazines with 9-allyl-1,7-,9-allyl-1,2-dicarba-closo-dodecaboranes and 1-allyl-2-isopropyl-1,2-dicarba-closo-dodecab-orane have been studied. The pyridazines containing carborane cage have been synthesized for the first time \\\\expert2\\nbo\\Russian Chemical Bulletin\\2010, 58 (1), 116-121.pdf |
E 43 Electrochemical sensor based on metal-containing receptors for urea measurements [Text] : доклад, тезисы доклада / A. Kozitsina [и др.]> // International Congress on Analytical Sciences "ICAS - 2006",M., June 25-30 2006 : book of abstracts. - М., 2006. - Vol. 1. - P291 : табл. - Bibliogr. : p. 291 (1 ref.) Рубрики: ХИМИЧЕСКИЕ НАУКИ |
U 62 Unusual Expansion of the 1,2,4,5-Tetrazine Ring in [1,2,4]Triazolo[4,3-b]-[1,2,4,5]tetrazines Leading to [1,2,4,6]Tetrazepine Systems [Text] / I. N. Ganebnuikh, S. G. Tolshchina, R. I. Ishmetova, N. K. Ignatenko, P. A. Slepukhin, G. L. Rusinov, V. N. Charushin> // European Journal of Organic Chemistry. - 2011. - № 12. - P2309-2318. - Bibliogr. : p. 2318 (22 ref.) Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: Expansion of the tetrazine ring has first been found to occur when [1,2,4]triazolo[4,3-b][1,2,4,5]tetrazines were allowed to react with CH-active compounds in acetonitrile in the presence of triethylamine to give the unexpected series of 8,9-dihydro-7H-[1,2,4]-triazolo[4,3-b][1,2,4,6] tetrazepine derivatives \\\\Expert2\\nbo\\European Journal of Organic Chemistry\\2011, p.2309.pdf |
T 71 Tolshchina, S. G. 1,2,4,5-tetrazines and azolo[1,2,4,5]tetrazines: Synthesis and reactions with nucleophiles [Electronic resource] / S. G. Tolshchina, G. L. Rusinov, V. N. Charushin> // Chemistry of Heterocyclic Compounds. - 2013. - Vol.49, №1. - P66-91 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): 1,2,4,5-TETRAZINES -- AZAPHILIC ADDITION -- NUCLEOPHILIC SUBSTITUTION Аннотация: The literature data are summarized for synthetic methods and nucleophilic transformations of 1,2,4,5-tetrazines and azolo[1,2,4,5]tetrazines published predominantly from 1995 until 2012 \\\\Expert2\\NBO\\Chemistry of Heterocyclic Compounds\\2013, v.49, N 1, p. 66-91.pdf |
S 98 Synthesis and transformations of cyanomethyl-1,2,4,5-tetrazines [Electronic resource] / S. G. Tolshchina, R. I. Ishmetova, A. V. Ignatenko, A. V. Korotina, P. A. Slepukhin, V. N. Charushin> // Chemistry of Heterocyclic Compounds. - 2013. - Vol.49, №4. - P604-617. - Библиогр.: с. 617 (18 ref.) Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): S-TETRAZINE -- MALONODINITRILE -- NUCLEOPHILIC SUBSTITUTION Аннотация: Derivatives of s-tetrazine containing malonodinitrile, ethyl cyanoacetate, and 1,3-indanedione fragments were synthesized by the nucleophilic substitution of heterocyclic groups in 3,6-diazolyl-1,2,4,5-tetrazines. Coordination compounds of the cyanomethyltetrazine anion with Cu+, Mn2+, and the tetrathiafulvalene radical cation were obtained, and their structures were determined. A transformation of cyanomethyltetrazines to pyrrolo[1,2-b][1, 2, 4, 5]tetrazines catalyzed by metal cations was discovered \\\\expert2\\NBO\\Chemistry of Heterocyclic Compounds\\2013, v.49, N 4, p. 604-617.pdf |
S 90 Study of the supramolecular structures of complexes of carborane-containing pyridazines with 2,3,5,6-tetrachloro-1,4-dihydroxybenzene [Electronic resource] / P. A. Slepukhin, S. G. Tolshchina, A. V. Ignatenko, E. F. Zhilina, V. N. Charushin> // Crystallography Reports. - 2014. - Vol.59, №2. - С. 202-206. - Bibliogr. : p. 206 (9 ref.) Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): PYRIDAZINES -- HETEROCYCLIC SUBSTITUENTS -- CARBORANE MOIETY Аннотация: The structures and characteristic features of the molecular packing patterns of complexes of pyridazines containing heterocyclic substituents and the carborane moiety with 2,3,5,6-tetrachlorohydroquinone (TCHQ) were investigated. It was shown that TCHQ can form supramolecular assemblies with carborane-containing substituted pyridazines. The stoichiometry and three-dimensional structures of these assemblies depend on the substituents in the pyridazine ring and are formed via O-H⋯N hydrogen bonding between TCHQ and heterocyclic molecules \\\\expert2\\NBO\\Crystallography Reports (Кристаллография)\\2014, v.59, N 2, p.202-206.pdf |
S 90 Study of the supramolecular structures of complexes of carborane-containing pyridazines with 2,3,5,6-tetrachloro-1,4-dihydroxybenzene [Electronic resource] / P. A. Slepukhin, S. G. Tolshchina, N. K. Ignatenko, R. I. Ishmetova, G. L. Rusinov, E. F. Zhilina, V. N. Charushin> // Crystallography Reports. - 2014. - Vol. 59, № 2. - С. 202-206. - Bibliogr. : p. 206 (9 ref.) Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): MOLECULAR PACKING PATTERNS -- PYRIDAZINES CONTAINING HETEROCYCLIC SUBSTITUENTS -- TETRACHLOROHYDROQUINONE Аннотация: The structures and characteristic features of the molecular packing patterns of complexes of pyridazines containing heterocyclic substituents and the carborane moiety with 2,3,5,6-tetrachlorohydroquinone (TCHQ) were investigated. It was shown that TCHQ can form supramolecular assemblies with carborane-containing substituted pyridazines. The stoichiometry and three-dimensional structures of these assemblies depend on the substituents in the pyridazine ring and are formed via O-H…N hydrogen bonding between TCHQ and heterocyclic molecules \\\\expert2\\nbo\\Crystallography Reports (Кристаллография)\\2014, v.59, N 2, p.202-206.pdf |
Synthesis of novel [1,2,4]triazolo[1,5-b][1,2,4,5]tetrazines and investigation of their fungistatic activity / A. V. Korotina, S. G. Tolshchina, R. I. Ishmetova [et al.]> // Beilstein Journal of Organic Chemistry. - 2022. - Vol. 18. - P243-250 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: A series of novel [1,2,4]triazolo[1,5-b][1,2,4,5]tetrazines has been synthesized through oxidation reaction of the corresponding 3,6-disubstituted 1,2,4,5-tetrazines bearing amidine fragments. It is shown that the heterocyclic systems obtained can be modified easily at C(3) position in the reactions with aliphatic alcohols and amines. Also, the reactivity of [1,2,4]triazolo[1,5-b][1,2,4,5]tetrazines towards CH-active compounds has been studied. The obtained triazolo[1,5-b]annulated 1,2,4,5-tetrazines proved to be active in micromolar concentrations in vitro against filamentous anthropophilic and zooanthropophilic dermatophyte fungi (Trichophyton, Microsporum and Epidermofiton), which cause skin and its appendages (hair, nails) diseases. |