In the present work by the examples of typical representatives of biostimulated and biocontrolled mineralization products (conodonts, fossil stromatolitic formations, modern cyano-bacterial mats, modem human tooth tissues) a method of sample preparation and multielement microanalysis by ICP-MS is developed. Obtained data is analyzed on the basis of crystal chemistry and lithological-geochemical approaches. Introduced analytical methods can be used for microelement composition investigations of fossil phospate and carbonate biominerals.